Stephanie Xie
@stephxie
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Scientist, mom and partner. Hematopoietic stem cells enthusiast. Orchids too.
Toronto, Ontario
Joined July 2009
I am thrilled to announce I am the newest Scientist @pmcancercentre. The Xie lab will focus on understanding how inflammatory and metabolic stress in human hematopoietic stem cells promote aging and cancer risk and preventative interventions. Recruiting…
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Preprint alert🚨‼️.I am beyond thrilled to share with the 🧪 community the characterization of ATP2B1, a new human immunophenotypic long-term 🩸hematopoietic stem cell marker across ontogeny in fetal liver, cord blood and adult sources. #proudmentor.
Excited to announce our latest preprint is finally out! Huge collaborative work shared with @MurtazaNagree and supervised by @stephxie! 😍 .Check it here! .@UofT @UHN @pmcancercentre.
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RT @andygxzeng: Excited to see BoneMarrowMap out in press! . Please check out the R package (now capable of classifying 100,000 hematopoiet….
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IRE1α–XBP1 moonlighting to restrict leukemia I’m happy to share a News&views I penned on an elegant study from Stanley Adoro and colleagues. @NatImmunol #AML #HSC.
IRE1α–XBP1 signaling safeguards the integrity of the blood system by restricting pro-leukemogenic programs in HSPCs @NatImmunol @brendanmbarton @AkankshaVe.
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RT @SvenTurkalj: 🔥Pre-print🔥. We show that therapy-resistant clones are selected within 1-3 cycles of IVO+VEN+/-AZA, months or years before….
biorxiv.org
Acquired resistance to targeted non-intensive therapies is common in myeloid malignancies. Yet, key questions remain as to how rapidly resistant clones are selected by treatment and in which hemato...
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RT @SayyamNShah: Super excited to present at my first ASH #ASH24!. Check out our poster, where we compile half a million HSC/MPPs to charac….
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RT @angelica_varesi: Looking forward to presenting my PhD work at #ASH2024! .If you want to hear more about the discovery of a new LT-HSC f….
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@angelica_varesi @SayyamNShah I am honored to have been selected to serve on the @ASH_hematology Scientific Committee for Stem Cells and Regenerative Medicine for the next 4 years, officially starting 2025. Proud to represent 🇨🇦 #HSC. @PMResearch_UHN.
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@angelica_varesi @SayyamNShah I’m so excited to moderate Sunday’s #ASH24 501 HSPC session with Kenichi Miharada.
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Superstar grad student @angelica_varesi will present her first oral, abstract 28 in the 501 HSPC session on Saturday. @SayyamNShah will wow you with his ML deep dive on HSC heterogeneity at poster 1281 in the Sat session. 2/.
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I’ve migrated to 🦋 #ASH24 posts will be there. #ASHThrowback 10th wedding anniversary fell on Thursday of #ASH2018. What to do? Husband is also #STEM 🧪academic, so understood the importance of an oral at ASH. Celebrated in SD in 🩸style with little red dress @ASH_hematology
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I was delighted to present a seminar @BCCancer and meet so many fantastic trainees. Thanks to @KarsanAly for the invitation and @WengLabBCCA for hosting. Dinner was wonderful at Published on Main with Andy and @hirstma.
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RT @andygxzeng: I’m excited to share an R package that we’ve created for mapping scRNA-seq data across normal and malignant hematopoiesis!….
github.com
A single cell RNA-seq reference map of human hematopoietic development in the bone marrow, with balanced representation of hematopoietic stem and progenitor cells and differentiated populations - a...
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A remarkable symposium celebrating the 40th anniversary of T cell receptor discovery by #TakMak. @ImmunologyUofT @MBPatUofT @pmcancercentre
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Really beautiful work from @PapapetrouMDPhD and team tracing venetoclax resistance in AML to RAS mutations.
🎉Excited to present our latest work out today @Nature 1.What gives a leukemia its phenotype – the oncogenic driver or the differentiation stage of the cell-of-origin? 2.Why do RAS mutations always happen late in AML? 3.Who will relapse after VEN?
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RT @JosephEStiglitz: 82 Nobel laureates in chemistry, medicine, physics and economics wrote a letter strongly supporting @VP @KamalaHarris….
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Ascorbate deficiency enhances HSC self-renewal. Congratulations to @StefanoComazze1 and @SJMorrison_ on this terrific @BloodJournal story showing the importance of metabolites to HSC fate! 🙏 for including @surajbansal2003 and I.
I am super happy that my last work in @SJMorrison_ lab is now out in @BloodJournal I am grateful to all the group members and collaborators that helped us during the years.
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Incredibly proud of @angelica_varesi and @SayyamNShah for their @ASH_hematology abstract achievement awards. I have the privilege of mentoring Angelica (2nd year of PhD @UofT w/ an oral presentation) and Sayyam (undergrad!!! @UWaterloo w/ a poster) with John Dick. #ASH24
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RT @jen_keesmaat: To put the bike lane debate in Toronto in perspective, more people commute by bike each day in Toronto than the entire po….
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