Michael Lab
@GenomesLab
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Todd P Michael @salk, #plant #genomes, #biology, #CircadianRhythm, #genomics
La Jolla, San Diego
Joined October 2018
Happy #420, today we release 22 pairs of high-quality chromosome resolved haploid #Cannabis #genomes (10 USDA lines) available to researchers through GRIN. All assemblies include gene models & repeat annotations @salkinstitute, https://t.co/fESNHNwDky
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If you do #pangenomes check out this new tool PanKmer led by @ScienceGuyTony from @GenomesLab @salkinstitute really awesome to see this applied to many large datasets across different species so far!! #genomics
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Awesome time at Salk and collecting Welwitschia at @TheHuntington with @jleebensmack @GenomesLab. More sex chromosomes !
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A thread about using color as a design tool in science presentations. Color is a great tool to separate different categories of information, to highlight information, or to establish an emotional tone. š§µ1/20
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Great job @MaliaMoore23 discussing #seagrass #genome and #chemistry @GenomesLab @Scripps_Ocean @salkinstitute
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Kit 14 will allow users to tune their accuracy & output needs by modifying run conditions in the software. Early work has shown 99.6% raw read accuracy can be achieved at 28 degrees. At 34 degrees, 99.3% is possible whilst generating a high yield. Watch:
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Our take on r10 nanopore sequencing for bacterial genome assembly. Comparing r9.4.1, r10.3, r10.4, and illumina. Including HAC, SUP and DUPLEX basecalling. DUPLEX could replace hybrid assemblies, but yields need to improve. With @NicStoesser and @ModMedMicro
Comparison of R9.4.1/Kit10 and R10/Kit12 Oxford Nanopore flowcells and chemistries in bacterial genome reconstruction https://t.co/F0Cj5fYM00
#bioRxiv
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Extreme field biology: miniaturised equipment for DNA extraction, sequencing and analysis in the wild ( https://t.co/KvfjsVw6cR)
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Lots of great comparative genomics tools on display by ā¦@mike_schatzā© ā> also great to see a commitment to a deployment of tools to biologists via galaxyā© #AGBTAG22 ā¦@agbtā©
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Harnessing Plants Initiative: keys to carbon drawdown and storage #AGBTAG22 @salkinstitute @agbt ⦠deep roots, bigger roots, and more recalcitrant carbon rich polymers
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If you're interested in #wildcaught #fish #microbiomes, check out our @biorxivpreprint: "Fish microbiomes 101: disentangling the rules governing marine fish mucosal microbiomes across 101 species" https://t.co/5DFdZwr5qr
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Took me about 10 #fish #genomes to get dialed in but finally making some ultra long dna and libraries ā latest 83 kb N50 on #promethion @nanopore
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Profs Joseph Noel + Todd Michael are showing how their research will help build a roadmap to preserve & restore wetlands around the world, using native plants that can withstand current and future climate conditions. @SpecNews1SoCal
https://t.co/YFmCKedgyI
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Welcome #PAG attendees! Virtual #PAGXXIX is happening now. Please be patient, as we are still working out the bugs. Virtual PAG XXIX Workshop Sessions Registration is still open at: https://t.co/DsICczzRrP We hope you join us.
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Postdocs in computational, evolutionary, and disease genetics: apply to be in the Rising Stars in Genetics and Genomics Symposium at the U of Utah (May 11-12). We want to host creative, early career scientists to share their exciting science.
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Follow the action at #nanoporeconf @NanoporeConf š§¬
I just got my ticket for the @nanopore community meeting. I've heard that poster No. 19 is gonna be quite interesting. Don't forget to pass by and find out what it is about! (or if this is just a shameless self-promoting tweet)
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Accuracy often gets a lot of attention when talking about the most recent release of @nanopore chemistry. However, I think it is a game changer that now only 5 fmol of DNA is loaded onto the flowcell. For 10 kb DNA fragments that is down to 31 ng!!!
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How do plants 'breathe' underwater? š ERC grantee @Jan_de_Vries @uniGoettingen sequenced the genome from aquatic plants called #Quillwort,enlarging our understanding of how they compete for carbon dioxide underwater. Read more about his research š https://t.co/qBoZxAp04D
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