Freddy Frischknecht
@FrischknechtLab
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Cell biologist working on malaria parasites and interest in host pathogen interactions, imaging, teaching, space exploration, gardening
Heidelberg
Joined July 2019
‘Phone addiction’, the new #pandemic and my daughter’s new parasitic ‘earworm’ song: https://t.co/XRFlYdFlYf
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I am now at @freddyfrischknecht.bsky.social. But wanted to share a last wish granted: I always wanted to name a protein after a Greek goddess or nymph and here we go: https://t.co/myuQLnwOkD Happy holidays everyone
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Wonderful personal science story. More people should write them. Congrats Misha.
Take a look at my personal perspective on the past, present, and future of in situ structural biology with cryo-ET+ While initially skeptical about the genre, I found it fun to write and hopefully, you can enjoy my experiences and some thoughts. Nice WE! https://t.co/v7Upk35UOt
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How come we know so little about a protein that is the basis for the currently available malaria vaccines? New review on the Plasmodium circumsporozoite protein, with Photini Sinnis and Mirko Singer out now: https://t.co/VATHFYgKlu
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You can celebrate success in science as if it's sports. So proud and happy for the amazing students @UniHeidelberg and their fearless leaders. What a joy to watch.
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🎉 We're excited to announce the brand new EMBO | EMBL Symposium 'Infection: pathogens, hosts, and microbiomes'. Join #EESInfection and be part of discussions that will fertilise the transfer of technologies across fields. Learn more and register: ➡️ https://t.co/oZMTqJePpm
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Go @MBLBoP 2025
Excited to announce that our 2025 Advanced Research Training Course schedule is up and applications are open! 🎉🎉🎉 See you in Woods Hole! https://t.co/9cAcnqoAfG
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I stared off doing neuroscience and dwindled into the abyss of infection research. So happy that @MishaKudryashev took up the torch.
Our tetrameric forms of the serotonin receptor 5-HT3R made it to the cover of the @embojournal ! Paper here: https://t.co/wCzUlhcMKg It's our first cover and the first one since my PhD. Freddy @FrischknechtLab shall be proud of me :)
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Now out in @NaturePhysics: great work by @clhueschen, Rob Phillips, @Dunn_Lab and coworkers on gliding motility of apicomplexa, combining imaging of surface flows with continuum mechanics modeling. Read the open access paper here
nature.com
Nature Physics - Unicellular parasites, such as Toxoplasma gondii, can use different forms of gliding motions when infecting a host. These motility modes arise from the self-organizing properties...
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New preprint with @SchwarzUlrich and @RippJohanna for @ParasitePhysics: Traction force generation in motile #malaria #parasites is modulated by the Plasmodium adhesin TLP. Sporozoite still running in circles, but in many colors. Red: strong force. https://t.co/y1WJSgK2yt
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Looking forward to an exciting two weeks of infection conferences @embl in May. This one just following the classic BioMalPar. For people from far away, why not stay for both?
🎉 We're excited to announce the brand new EMBO | EMBL Symposium 'Infection: pathogens, hosts, and microbiomes'. Join #EESInfection and be part of discussions that will fertilise the transfer of technologies across fields. Learn more and register: ➡️ https://t.co/oZMTqJePpm
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Can’t be at MPM24 @parasitesrule so sending greetings with @MBLBoP 24 Tshirt. Please all: give big hugs to David Roos and @omartheharb for their incredible efforts towards keeping @veupathdb up and running.
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After 4 years of revisions (ok, not exactly working 24/7 on it) @KehrerJessica and @_emma_pietsch_ got this manuscript to the next level. Using APEX-based proximity labelling in #malaria #parasites we found a new protein important for Plasmodium gamete egress+ookinete migration.
APEX-based proximity labeling in Plasmodium identifies a membrane protein with dual functions during mosquito infection https://t.co/owFEkGJWlU
@FrischknechtLab
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Happy to see our first 'blendered' cover out @EmboMolMed featuring an 8 year journey towards a new type of attenuated #malaria #parasite: https://t.co/rozkhz1WBf - just wondering what that ring is doing there
embopress.org
imageimageThe two vaccines currently employed against malaria are based on a single Plasmodium antigen, require 4 shots and provide only limited protection. Attenuated whole parasite vaccines are...
Our September issue is online! This month's cover highlights the article by J. M. Sattler, F. Frischknecht and colleagues @FrischknechtLab on vaccination against #malaria Scientific illustration by Marco Binder @TheBinderLab 🗞️ https://t.co/9sWOQ10ctb
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CONGRATS to @FHentzschel for obtaining an @ERC_Research starting grant to work on the 'weird' but wonderful biology of the Arp2/3 complex in #malaria #parasites: https://t.co/qsgJtcCZRp
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My 5 cents on #parasites translated from the original German by AI (making it a 'funny' read) as a short introductory text for non-experts: https://t.co/4POJK2lbik
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What happens when you apply design principles from bottom-up synthetic biology to immunology? In Heidelberg and together with @FrischknechtLab @platten_michael & Oliver Fackler we compiled the prospects of bottom-up synthetic immunology @NatureNano
https://t.co/uRh8BpMksX
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just WOW
Marine algae Prymnesium parvum use massive enzymes dubbed PKZILLAs—some of the largest proteins ever to be identified in nature—to make complex prymnesin neurotoxins responsible for mass fish kills during harmful algal blooms, a new Science study finds. https://t.co/nSJEEjQ0MS
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Thanks, I like the red cell basketball
Scientists are outsmarting malaria by training our immune system with weakened parasites, turning the tables on this deadly foe. https://t.co/sFbPtoZ2cn
@FrischknechtLab @AbdelrahimAiman @FHentzschel @LuisaZechel @CiidHeidelberg @EmboMolMed
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So happy to have started this a long time ago along a great group of PhD students. Do participate at this amazing meeting in the year EMBL turned 50.
The early bird registration for the EMBL PhD symposium is still open until the 10th of August! You can find the registration link and further information on our website! #emblphdsymposium #biologyoutsidethebox
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