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Fernando de la Cruz Profile
Fernando de la Cruz

@FdlC61

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Plasmid Biology

Santander, Spain
Joined February 2015
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@FdlC61
Fernando de la Cruz
3 months
🌾🦠 Seeds carry more than genes! We provide the first experimental proof that Pantoea bacteria are vertically transmitted across wheat generations via seeds β€” the first such evidence in cereals. πŸ“„ Read: https://t.co/R1ZDpkvlbD #PlantMicrobiome #SeedBiology #Endophytes
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academic.oup.com
Abstract. Plant-associated microorganisms, particularly endophytes, are essential for plant health and development. Endophytic microbiota is intimately ass
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@wfigueroac3
Wendy Figueroa
2 months
Thrilled to share our latest paper now out in @ScienceMagazine πŸŽ‰πŸ€© We investigated a century of plasmid evolution 🧬 and uncovered how they have adapted to the antibiotic era πŸ’Š
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science.org
Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data...
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@FdlC61
Fernando de la Cruz
3 months
4/ Why it matters: πŸ”Ή Vertical transmission = stable, inheritable plant–microbe partnerships πŸ”Ή Potential roles in plant health, adaptation, and evolution πŸ”Ή Opens new routes for microbiome-based crop improvement #Microbiology #Agriculture #FoodSecurity
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@FdlC61
Fernando de la Cruz
3 months
3/ Experimental breakthrough: βœ… Labelled Pantoea inoculated in parent plants βœ… Detected in next-generation seeds & seedlings ➑ This experimentally demonstrates specific intergenerational (vertical) transmission.
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@FdlC61
Fernando de la Cruz
3 months
2/ Pantoea is the unique core endophyte in wheat seeds worldwide. 🌍 Detected in seeds from diverse origins 🌱 Persists in roots, shoots, spikes, and seeds πŸ“ˆ Its relative abundance increases across plant tissues
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@amazeld
Didier Mazel
3 years
What a NAR issue! 2 - check out the NAR paper by @FdlC61 group on how increase specific targetting by conjugation in complex populations by the expression on the surface of donor of specific nanobodies (Nb) ! https://t.co/KAJjsLK1G1 Congrats to all!
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academic.oup.com
Abstract. Genetic interventions on microbiomes, for clinical or biotechnological purposes, remain challenging. Conjugation-based delivery of genetic cargo
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@alice_ledda_
AliceLedda, PhD πŸ’™
3 years
Who else than @FdlC61 could be in the team behind this amazing proof of concept?!? Plasmids rock!
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@alice_ledda_
AliceLedda, PhD πŸ’™
3 years
Great news on the second edition of the "Workshop on plasmids as vehicles of AMR spread" are coming soon!! Stay tuned!! @zi @FdlC61 @FabBenz @yekwah @jpjhall @livkosterlitz @AlvSanMillan @nquinoneso
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@ruizalb
Alberto Ruiz-Jimeno
4 years
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@FdlC61
Fernando de la Cruz
4 years
It will help us understand the role of plasmids in more complex microbiota, such as the human gut DOI: 10.3390/jcm9051369
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@FdlC61
Fernando de la Cruz
4 years
This is our start in the analysis of microbial communities. Our next aim will be to assess the roles of the #plasmidome in the evolution of these model communities. #Plasmids provide adaptive functions in these and many other consortia
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@FdlC61
Fernando de la Cruz
4 years
Isolation and phenotypic and genomic characterization of Tetragenococc...
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@alice_ledda_
AliceLedda, PhD πŸ’™
4 years
Happy Pi Day!! Tomorrow is the deadline for the application to the "Workshop on plasmids as vehicles of AMR spread!" If in doubt, do apply! @ictpnews @MRC_Outbreak @Imperial_IDE @Imperial_Jameel Co-organiser @FdlC61 @ZaminIqbal
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@alice_ledda_
AliceLedda, PhD πŸ’™
4 years
Just one week left to apply!! Deadline March 15!! "Plasmids as vehicles of AMR spread" https://t.co/XW9MSiaDgt March 21st-25th only online!! A collaboration @ictpnews @MRC_Outbreak @Imperial_IDE Co-organisers @ZaminIqbal @FdlC61
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@alice_ledda_
AliceLedda, PhD πŸ’™
4 years
11 days left to apply!! Deadline March 15!! "Plasmids as vehicles of AMR spread" https://t.co/XW9MSia5qV March 21st-25th only online!! A collaboration @ictpnews @MRC_Outbreak @Imperial_IDE Co-organisers @ZaminIqbal @FdlC61
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@alice_ledda_
AliceLedda, PhD πŸ’™
4 years
The workshop on "Plasmids as vehicles of AMR spread" is finally on!! March 21-25, 2022 - Online only Info & applications (deadline March 15): https://t.co/XW9MSia5qV @MRC_Outbreak @Imperial_IDE @ictpnews Co-organisers: @FdlC61 @ZaminIqbal
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@alice_ledda_
AliceLedda, PhD πŸ’™
4 years
Finally, two years after, great news on the workshop are coming soon!! Stay tuned!!! @ictpnews @MRC_Outbreak @FdlC61 @ZaminIqbal
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@FdlC61
Fernando de la Cruz
4 years
We now report on the in vivo activity of conjugation inhibitors (COINs):
journals.asm.org
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@FdlC61
Fernando de la Cruz
4 years
The web link to operate COPLA: https://t.co/QbxH9bePu9
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