Emma Vincent
@EmmaEVincent
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Diabetes UK RD Lawrence research fellow @Brms_Research at the University of Bristol. Views my own.
Bristol
Joined October 2012
Lovely to see our @DUK_research on the beginnings of type 2 diabetes out in @ADA_Journals. Excellent thread by @joshuaa_bell below. Also nice to see it in @thetimes this morning! @CMMBristol @DiabetesUK
Ever wonder how diabetes begins? Our new paper in @ADA_Journals looks at effects of being more genetically prone to adult diabetes on metabolism across early life. We found signs of disease liability ~50 yrs before peak onset. https://t.co/ctpfgaFx9h
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Interested in a PhD on colorectal cancer prevention at the University of Bristol? Details here: https://t.co/fqZQAuB7WC. Supervised by myself, @AdamCChambers1 and @drlaura_thomas.
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Just over one week left to apply for our 3-year post-doc post in molecular #epidemiology of adiposity-driven pancreatic cancer at @imperialcollege. Further info below - get in touch if interested! @r_martin_ @Karl_SmithByrne @ECSanderson @EmmaEVincent
We are re-advertising for an exciting 3-yr postdoc post at @imperialcollege using molecular #epidemiology to understand adiposity-driven pancreatic #cancer. Competitive salary and hybrid working options. Deadline 4/11. Email if interested! Pls retweet🙏 https://t.co/a9lkof1DX3
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[3/4] Emma Vincent & Javier Gonzalez will use a Prevention and Population Project Award to measure molecular intermediate responses from previous short-term dietary intervention trials to assess the effect of a ketogenic diet on colorectal cancer outcomes. #CRUKFunded
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We have an exciting 3-yr postdoc position at @imperialcollege using molecular #epidemiology to understand adiposity-driven pancreatic #cancer. Possibility of hybrid working. Deadline 24/07 @Mattias31 @r_martin_ @Karl_SmithByrne @EmmaEVincent Pls retweet🙏 https://t.co/GXUhF1j6Rm
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Editor pick from February issue @EmmaEVincent @caroline_bull @EpiHazelwood & coll Report that intentional weight loss among individuals with recently diagnosed diabetes may modify levels of cancer-related proteins in serum. Read https://t.co/JCRUMWjS9C
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Fantastic to see both of these papers out, @EpiHazelwood has done such a great job getting these over the line! Thanks to @DUK_research, @WCRF_UK and @CR_UK for funding.
Really pleased to see our paper published in @eBioMedicine this week. We found that weight loss in people recently diagnosed with type 2 diabetes altered levels of cancer-related proteins in blood🩸. https://t.co/HBXwcHq1AY
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Thanks to all co-authors, supervisors and examiners! And thanks to @GW4BioMedDTP for funding Andrei's PhD! @caroline_bull @nic_timpson @Nickjonesimmuno @N_Murphy @PaulYousefi
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Double congrats to @_andreicon for his second PhD paper https://t.co/oUqXF5BnS1 looking at the relationship between white blood cell traits and colorectal cancer and for passing his viva this month! An eosinophil cake was called for to celebrate. @GW4BioMedDTP
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👉 job opportunity 👈 Pleased to let you know we have postdoctoral research associate position available in the @BristolPlatelet to develop PROTAC-mediated protein degradation approaches in human platelets. For further details 👇 https://t.co/65pXeIVzDh
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Really pleased to see this out! SGLT2 inhibitors are really starting to look interesting... @BrisCancerEpi @BristolRenal @DUK_research
👋🏻 Excited to share my lab’s first (!) work today published in @Cell_Metabolism where we demonstrate that the type 2 diabetes drug, canagliflozin, impairs human T-cell effector function via metabolic suppression led by @B_J_Jenkins –
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As usual both papers a result of team effort. @N_Murphy @Nickjonesimmuno @joshuaa_bell @MCarol_Borges @nic_timpson @DimouNiki and many more!
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and @EpiHazelwood and @caroline_bull have an epic reverse Mendelian randomization effort looking to understand what genetic liability to colorectal cancer looks like at the level of the circulating metabolome. Thanks to @CR_UK for Emma's PhD funding.
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@_andreicon has a lovely paper on white blood traits. Andrei uses observational and Mendelian randomization methods to show that a higher eosinophil count might protect against colorectal cancer. Thanks to @GW4BioMedDTP for Andrei's PhD funding.
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It's been a busy week for the group! 2 new preprints out on better understanding colorectal cancer risk https://t.co/FCsKIK5Sfc
medrxiv.org
Recognizing the early signs of cancer risk is vital for informing prevention, early detection, and survival. To investigate whether changes in circulating metabolites characterise the early stages of...
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Now published in @BMCMedicine! https://t.co/JRDHctZgFj Thanks again to @iTomRichardson @N_Murphy @EmmaEVincent @joshuaa_bell @ECSanderson @NeliMUlrich @nic_timpson @mendel_random @IARCWHO @BrisCancerEpi @mrc_ieu @WCRF_UK and many others
bmcmedicine.biomedcentral.com
Background Observational studies have linked childhood obesity with elevated risk of colorectal cancer; however, it is unclear if this association is causal or independent from the effects of obesity...
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Don’t miss this free online talk on 6 December @ 7pm. @EmmaEVincent will be discussing the links between #type2 #diabetes and #cancer. Find out more and register here: https://t.co/6a8Kq7keqi
#event #health #research
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PhD opportunity! If you're interested in diet, nutrition and colorectal cancer we have a PhD project advertised: https://t.co/BN10aOqlRG You can find the project here: https://t.co/6RK3NQFSm8 Get in touch for more info! Closing date 5th Dec.
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As always a fantastic team effort! Current and past @Bristol_CTB group members, @Nickjonesimmuno, @owen_sansom, @leggey86, @Flanagan_Lab, Rafa Nujumudeen and Madhu Kollareddy.
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CB-839 had almost no effect at all alone and so raises the question of whether aspirin could be a simple and cost effective way to increase efficacy of CB-839?
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