Dusty Flanagan
@Flanagan_Lab
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If adult #stemcells are rock stars of #gut and #stomach, the Flanagan Lab studies how ‘roadie’ #stromal cells support them in #homeostasis + #cancer 🔬🧬
Melbourne, Australia
Joined August 2022
RT @CMitoKnight: Be part of building the new ASSCR website. Submit your images, and ideas for a slogan before Aug 30th.
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RT @the_ASSCR: 🚨 Final Reminder! 🚨. Last day to submit your abstracts and apply for awards for the #ASSCR2024 Meeting!. Get your work in be….
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RT @neve_matt: PhD paper done and dusted! thanks to @RosenbluhSefi.and Ling Liu for the awesome mentorship and good times :) Check out our….
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RT @the_ASSCR: This is your 🚨 three-week warning 🚨 before abstracts close on August 16th for @theASSCR 2024 Meeting: .
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RT @the_ASSCR: Abstract deadline for our NSW EMCR Symposium is fast approaching, May 20th! Get your abstracts in before Monday! Rego for AS….
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RT @Rafabolism: Hey everyone - Pls RT - we’ve got a great position open for a talented #postdoc scientist to join us @HiLIFE_helsinki @hels….
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RT @the_ASSCR: 🚨Mark it down in your diaries folks: The 2024 @the_ASSCR Meeting will be held on November 11th-13th in Adelaide this year.….
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RT @the_ASSCR: This Wednesday don't miss our Final National Stem Cell Conversation for 2023, 6 Dec at 11 am AEDT. Hear from THREE of the AS….
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RT @AusStemCell: Listen: why do some stomach stem cells go rogue, leading to cancer? - #MetcalfPrizes winner @Flanagan_Lab @MonashBDI c….
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🎧 Catch me on ABC Radio Melbourne tonight from 8.30pm AEDT - I'll be chatting with @dontattempt David Astle about my research on rogue #stemcells in the #gut and #stomach. You can listen live here:
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RT @AusStemCell: 'Dusty' joins elite stem cell research company .@wangchronicle reports on #MetcalfPrizes winning s….
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Very humbled and honoured to receive the 2023 #MetcalfPrizes for our work on rogue #stemcells in the #gut and #stomach. A huge thanks to all past and current mentors and colleagues for your support!.
>> Can stem cells make drugs to stop osteoarthritis? Jiao Jiao Li @UTSEngage .>> Stomach stem cells behaving badly: Dustin Flanagan @MonashBDI.Congratulations to Jiao Jiao @JiaoJiaoLi_Syd and Dusty @Flanagan_Lab, the winners of our 2023 #MetcalfPrizes.
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RT @ReneaTaylor1: Thoroughly enjoyed the joint Monash/Peter Mac symposium today. Stimulating ideas around platform technologies, consumer e….
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RT @OrganoidsAreUs: Announcing Registrations are now open for Organoids are Us 2023!. #3DCellCulture.#organoids.#P….
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RT @DrPipDunne: Another bonus, the study has been selected as an “Editors’ Highlight” by @NatureComms and featured here: .
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Thanks to @owen_sansom @CRUK_BI, @DrPipDunne, Raheleh Amirkhah, @NurayGunduz7, @adcampbel1, @vanRheenen_Lab, @leedham_simon + everyone else involved to make this study possible. 8/8
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The clinical significance is for KRAS-mutant patients -- they don't normally respond to EGFR inhibitors. But if they also have high TGFB signalling, they will potentially respond to EGFR-targeted therapy. 7/n
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We thought these other pathways might offer new vulnerabilities that we could exploit with drugs. So that's what we tried in our mouse models. And it worked!. 6/n
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Q. Why does TGFB activation accelerate tumour growth? . A. Because it engages other growth-factor signalling pathways (such as EGFR/MAPK). 5/n
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