Colin Conine
@ColinConine
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Small RNA Biologist at the University of Pennsylvania and Children’s Hospital of Philadelphia
Massachusetts, USA
Joined March 2018
📢 JOB ALERT: Tvardovskiy Lab at @PennEpiInst is hiring at all levels! Interested in chromatin biology, quantitative proteomics, or epigenetic modifications? Learn more about our research and apply at https://t.co/cz0RcZ6PRM Please RT
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Please share broadly! We're looking for a new faculty member @MoGen_Grad! Those working on model systems, using genomics, computational and systems biology approaches are strongly encouraged to apply! Please reach out with any questions! @GeneticsGSA @RNASociety @RNACanadaC2R2
📢 We’re hiring! The Department of Molecular Genetics is looking for an Assistant Professor in Molecular Biology & Genetics at the @DonnellyCentre. 🔗 Apply here: https://t.co/W95z06jMGK 🗓️ Closing date: Dec 19. Please share and encourage great candidates to apply!
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Delighted to share the latest paper from the lab!!🤩 Big thank you to the entire team, Cheng Zhao,@SavBiondic. Perfect timing with the latest Nobel Prize for the discovery of miRNAs😊 @UMontreal @karolinskainst @CIHR_IRSC
nature.com
Nature Communications - This study provides a comprehensive analysis of small non-coding RNAs during human preimplantation development. It identifies key miRNA and snoRNA expression patterns,...
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Congratulations to our 2024 medicine laureate Victor Ambros ✨ This morning he celebrated the news of his prize with his colleague and wife Rosalind Lee, who was also the first author on the 1993 'Cell' paper cited by the Nobel Committee. #NobelPrize
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Nobel for miRNAs and another for the worm! Victor and Candy’s paper cloning lin-4 is my all time favorite (the Ruvkun paper is also incredible). The foresight in the discussion is 🤯. This could not have gone to a better scientist and person
BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
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Please nominate grad students for the @WeintraubAward!
The @WeintraubAward recognizes the outstanding achievements of grad students in biology and was established to honor the bold, creative, pioneering spirit embodied by Dr. Hal Weintraub. Nominations for 2025 are now open!
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Come join @montserrat , @TheModzLab , and the rest of us here in BMS!
📣The Dept. of Biomedical Sciences, Penn Vet is soliciting applications for a TENURE-TRACK junior faculty position. Candidates with interests in embryonic and adult stem cell biology & tissue regeneration and repair are encouraged to apply via Interfolio.
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Interested in piRNAs and transposon DNA methylation? Our new collaborative work revels a key mechanism underpinning the precision of piRNA-guided LINE1 methylation. Congratulation to all the authors! https://t.co/MMUkH3iATz
nature.com
Nature - In male mouse germline development, the precise DNA methylation of young, active transposons requires a two-step process in which SPIN1 and SPOCD1 mark young LINE1 elements before the...
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Wharton professor here! Here are the Penn Wharton Budget Model estimates: — Harris’ proposal increases the deficit by $1.2 trillion, with low- and middle income households benefiting disproportionately. — Trump’s proposal increases the deficit by $5.8 trillion. Details below 👇
Our latest briefs analyze the policy proposals of the Kamala Harris and Donald Trump campaigns for their economic, budgetary, and distributional effects over the next 10 and 30 years. https://t.co/AWjCgoXPFK
https://t.co/uJwE4gBNy5
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I had no idea the orange guy was a leader in field we dabble in “fertilization”
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🎙️ Check out the DASL Podcast , a platform dedicated to amplifying the voices of underrepresented trainees in academia! 🎙️ Tune in to hear the first 3 episodes filled with inspiring stories. Don’t miss out! #DASLPodcast #AmplifyVoices @czi @ucsddasl
🎙️ Excited to introduce the DASL Podcast, a platform dedicated to amplifying the voices of underrepresented trainees at UCSD! We dive deep into stories of resilience, overcoming challenges, and navigating the complexities of academia. #DASLPodcast
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Excited to have this published! We identify a subset of microRNAs acquired by sperm from the epididymal epithelium that regulate gene expression in preimplantation embryos > https://t.co/7TcbDK1GCs Huge thanks to @ColinConine for the support and guidance during this project
cell.com
Trigg et al. utilize a genetic approach to modulate sperm miRNAs in the male reproductive tract to examine their acquisition and regulatory functions post-fertilization. Embryos fertilized by sperm...
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@CellReports Epididymal miRNAs are crucial for embryonic gene expression, highlighting sperm's role in non-genetic inheritance. This research opens avenues for understanding paternal influences on offspring health, potentially transforming reproductive biotech and epigenetic therapies.
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The first publication exclusively from my lab! Led by the amazing @NATrigg (who I will let tweet more details)
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A ligation-independent sequencing method reveals tRNA-derived RNAs with blocked 3′ termini ft. @lordsga, @EmilyJoan18, @NATrigg, Grace Lee, @ColinConine & Roberto Bonasio (@PennCDB/ @PennEpiInst) & @JeremyWilusz (@bcmhouston) @PennGenetics @CHOP_Research
https://t.co/p6h5xvyuaO
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.@JDVance is the biggest chamaleon in the history of humanity….when I met first him his message was of being inclusive and pragmatic and has become a divider and and a hater…he has no right to talk about anyone else..he has to look himself in the mirror first and read his book.
BASH: Do you believe Kamala Harris is Black? JD VANCE: I believe Kamala Harris is whatever she says she is, but I believe, importantly, that President Trump is right that she's a chameleon
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A year and a child later, LIDAR is out! Thanks to everyone involved - especially Roberto. His unconditional support and great mentorship made this possible. @EmilyJoan18 @NATrigg @JeremyWilusz @ColinConine
https://t.co/CJjvgKHkwM
cell.com
Scacchetti et al. develop a ligation-independent cloning method (LIDAR) to sequence RNAs irrespective of their size or 3′ modifications. LIDAR reveals a class of long 3′ tRNA-derived fragments,...
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Online Now: A ligation-independent sequencing method reveals tRNA-derived RNAs with blocked 3′ termini https://t.co/RsWUdloQ4R
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