RT @proxidrugs: 🎙️Honored to enjoy insightful presentations on “RNA-based therapeutics” & “New targets & therapeutic approaches” on day 2 o….

We are making a move ➡️🦋.Follow us there:

🤩It's out! Check out our latest paper describing an optimised #CRBN that we used for high-throughput drug screening and developing new chemo-proteomic assays. #HTS #TPD @proxidrugs @IBC2_GU @goetheuni

*See, share, register* for the Frankfurt Conference on Quality Control in Life Processes, 24-27th of March. The speaker's lineup looks amazing already!! 🤩.👉Registration before 1st of December: #FCQC2025 #autophagy #proteostasis #ubiquitin.

RT @sfb1177: Excited to announce the keynote speakers at #FCQC2025!.Aaron Ciechanover from @TechnionLive and @dixitvishva from @genentech….

RT @sfb1177: 🔔 Registration deadline approaching!.Don't miss out and secure your spot now!.🔗 #FCQC2025.

The 2024 #Proxidrugs annual retreat was once again a great chance to meet our colleagues from the consortium. A big shout out to our team members who represented us on stage @acjacomin @GiulioGiulian16 Henry Bailey @mohitasya @shahvarun28 .#Cluster4Future @proxidrugs @IBC2_GU

7th year in a row that Ivan is on the @Clarivate Highly Cited Researchers list. Congratulations @iDikic2 , and a big thank you to all the team members, past & current collaborators and colleagues. #HighlyCited2024 @ClarivateAG @goetheuni @IBC2_GU.

RT @iDikic2: How changes in kinetics of #splicing can lead to proteotoxic cell death & what is the role of #ubiquitination and ER-phagy in….

@MPIbp @imbmainz @srcsb @mpi_hlr @KyushuUniv_EN @UCAS1978 @SFB1531 @EnableFrankfurt @dzhk_germany @proxidrugs @ProLOEWE @trr267 @BMBF_Bund @Fraunhofer.

We’re incredibly proud of this work and grateful to the amazing team behind it.🙌@IBC2_GU @goetheuni @CristianPG_mlg @iDikic2 @mixmue.@BrandesLab @JamesAOo7 @StainierLab @shahvarun28 @GiulioGiulian16 @acjacomin @WojtekGalej @ManuelKaulich @IEbersberger @ronaycetin @RayeneBerkane.

Excited to share our latest research published in @ScienceMagazine! Cryptic splicing can lead to proteotoxic stress, but how do cells cope? Our study uncovers the role of ubiquitination and ER-phagy in mitigating the effects of misfolded proteins.

RT @JT_MVieira: I am very happy to have had the opportunity to present our latest results on targeting #legionella with #protacs. Especiall….

We can’t wait for this conference!😍4 days to talk about quality control mechanisms, the interplay between #autophagy and #ubiquitin and emerging therapeutics utilising the ub system. Registration Deadline: 1st Dec #FCQC2025 @goetheuni.

RT @CristianPG_mlg: Really happy to take part of this amazing manuscript from @crypt_tales and @DiefenbacherL published in @oncogenejournal….

RT @alejo_fractal: I’m thrilled to share that my latest research paper has been published in PNAS! 📄 A big thank y….

RT @CristianPG_mlg: Really happy to contribute with mouse liver cancer models and human cancer data analyses to this amazing Cell paper fro….

RT @CellCellPress: Now online! IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion

And, of course, a huge thank you to all our collaborators and funders 🫶 @IBC2_GU @EnableFrankfurt @sfb1177.

We identified IRGQ as a key regulator of MHC-I quality control. Its absence enhances CD8+ T cell responses. Reduced IRGQ levels in hepatocellular carcinoma patients and mouse models lead to improved survival by promoting anti-tumour immunity. #CancerResearch #Immunotherapy.