Damián García-García
@DamGarGar
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Ph.D. student (@PMurawala / @MDIBL / @MHH_life ) (BSc. @libbunam & MSc. @biomedicasunam) Interested in Developmental Biology and Regeneration.
Salisbury Cove, Maine
Joined May 2020
RT @biorxiv_devbio: The essential role of connective-tissue cells during axolotl limb regeneration #biorxiv_devbio.
biorxiv.org
Axolotls ( Ambystoma mexicanum ) are known for their remarkable limb-regeneration abilities, which involve the formation of the blastema, a specialized structure consisting of progenitor cells...
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I want to thank my Ph.D. mentor, @PMurawala and all the co-authors in the manuscript. Without their work, this project wouldn’t be a reality! 🫶 . Let us know what you think 😀.
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• We conclude that CT cells are necessary for axolotl limb regeneration .• Establish a cell ablation system in the axolotl that can be combined with any Cre-specific line .• Provide a new database of the dynamics in CT cell expression over time.
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Given their importance, we characterized the molecular dynamics of CT cells over time and deposited this database into an interactive web platform 💻(.
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We then eliminated CT cells using the NTR/MTZ #ablation system. After the specific elimination of CT cells, limb regeneration was delayed or truncated, underscoring the necessity of these cells for #regeneration 🤯
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We defined the dynamic changes of cell identities within the blastema over time by using 10X #Xenium spatial transcriptomics. Immune cells predominate in the first stages, whereas CT cells gradually increment and become the predominant cell (~73%) at the late blastema stage 🤔
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RT @ItaiYanai: Data can be analyzed in endless ways, as this paper reminds us. So while our published paper reports one way to do it, it's….
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RT @JovenAraus: Great job @matosches team! The community appreciated your efforts 😃 Adeno-associated viral tools to trace neural developmen….
cell.com
Jaeger et al. expand the toolkit for neuroscientists working on non-conventional animal species. The authors establish a screening strategy identifying adeno-associated viral vectors (AAVs) for three...
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RT @glaevsky: Please RT!. We are very proud to announce LSFM 2025! The light-sheet conference/workshop will be held this year June 1st-7….
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RT @labonnelab: Mark your calendars - You won't want to miss this EPIC meeting - shout out to @nanibanani13 and @vazquezn14 for the beautif….
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RT @BioimagingNA: Virtual I2K starts next Monday, Oct 28!!!🎉. 34 exciting tutorials on #OpenSource #ImageAnalysis. Register (for free) toda….
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RT @ItaiYanai: Doing good science is 90% finding a science buddy to constantly talk to about the project.
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RT @Nature: Largest brain map ever reveals fruit fly’s neurons in exquisite detail
nature.com
Nature - Wiring diagram lays out connections between nearly 140,000 neurons and reveals new types of nerve cell.
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RT @HHMIJanelia: 🧪A team of researchers, led by @HelenFarrants & @ERSchreiter, developed a new way for engineered protein biosensors & brig….
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RT @mayetenorio_: ✨️ I’m excited to share my second-author paper encapsulating most of my PhD work, which is out today in @ScienceMagazine….
science.org
Long noncoding RNAs (lncRNAs) are essential regulatory elements of sex chromosomes that act to equalize gene expression levels between males and females. XIST, RSX, and roX2 regulate X chromosomes in...
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RT @voigtvision: Long awaited (thanks @JamesDManton for posting the patent application!) and now out in @ScienceMagazine: Using absorption….
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RT @priscaliberali: @schierlab and I are super happy to share this review for the 50th @CellCellPress. We really enjoyed working on it and….
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RT @mayor_lab: Pl spread the news: applications are open to the next version of the EMBO Practical Course on Developmental Biology, Quintay….
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RT @mayor_lab: To celebrate the 25 anniversary of this course we will host a special symposium with course alumni. If you have been a stude….
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