ChemBioNAC
@ChemBioNAC
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Chemical Biology and Nucleic Acid Chemistry Group at #IBMM @umontpellier @chimiebalard Group leader @Smietana_M
Montpellier, France
Joined December 2018
Had a great day visiting @DebartFrancoise and Michael Smietana at IBMM in Montpellier. 😊 Thank you for the invitation, the hospitality and the scientific discussions. 🧬🤩
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Our lastest article has just been released (Org. Biomol. Chem): Synthesis, duplex-forming properties, and enzymatic resistance of oligonucleotides containing N-acylsulfonamide linkages https://t.co/e4yMN25Xzy
@CNRSchimie @umontpellier @enscmchimiemtp @ChemBioNAC @IBMM_Balard
pubs.rsc.org
We report the synthesis of (2-(N-acetylsulfamoyl)ethyl)carbamate (NAC)-linked thymidine dinucleotide via the sulfo-click reaction and its incorporation into DNA oligonucleotides. Thermal denaturation...
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🎇Please meet our next 10th Euroboron invited speaker - Michael Smietana🎇 Michael is Professor at the University of Montpellier, France. His current research focuses on molecular recognition and nucleic acid bioconjugates, in particular boron-modified nucleic acids.
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Very pleased to share our latest publication on the Synthesis and Base-Pairing Properties of Oligonucleotides Containing 5′-(R)- and 5′-(S)-C-Aryl-thymidine now in JOC https://t.co/cS0sBPbXA3
@DebartFrancoise @VasseurJeanJacq @HausdorffMarcel @CNRSchimie @umontpellier @ChemBioNAC
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We have developed an entirely new mechanism of action for gene knockdown -> trafficking of targeted mRNAs to the lysosomal, using lysosomal trafficking oligonucleotides (LyTONs)! Published in @ChemicalScience Led by @disha_kashyap_, with @milnetom68
https://t.co/ciaFGwt5QG
pubs.rsc.org
Antisense oligonucleotides (ASOs) can modulate gene expression at the mRNA level, providing the ability to tackle conventionally undruggable targets and usher in an era of personalized medicine. A...
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Kudos to @PastorelZachary and Juliette Zanzi Great Team work with @OBasle @CanacYves @arseniyadis @elisejdumont and Alessio Bartocci @CNRS @umontpellier @IBMM_Balard @ChemBioNAC @LCC_CNRS @NiceChemistry
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🚨 Looking for a stimulating environment where your expertise in chemical biology can shine ? The Institute IBMM invites applications for 2 CNRS tenure-track positions. -> Glycochemistry -> RNA Chemistry contact : du-ibmm@umontpellier.fr To apply : https://t.co/jJYAfL15vL
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Very happy to share out new pre-print on the enzymatic GalNAc-labelling of oligonucleotides. Big congrats to undergraduate student Elisa and graduate student @pierrenicolas_b ! https://t.co/EIoFinvP7L
@institutpasteur @CNRSchimie
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🚨 Looking for a stimulating environment where your expertise in chemical biology can shine ? The Institute IBMM Balard invites applications for two CNRS tenure-track positions. -> Glycochemistry -> RNA Chemistry Contact : pascal.dumy@umontpellier.fr
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Very special scientific day on the occasion of @VasseurJeanJacq retirement. Thanks to the speakers for their great lectures and thanks to all the participants. Happy retirement Jean-Jacques !🌴☀️🚴 @umontpellier @ChemBioNAC @IBMM_Balard @Philippe_Auge @PascalDumy
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Fantastic lectures on photo-biocatalysis, transition-metal catalysis and organocatalysis at @UNamur chemistry department. Great dissussions with @GrimaudLaurence (ENS Paris), @Smietana_M (Univ Montpellier @ChemBioNAC), E McGarrigle (@McGarrigleGroup, UCDublin) and @OlivierRiant.
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Mini-symposium this Friday at the chemistry department of @UNamur. Three invited speakers: Prof. Smietana (@Smietana_M), Grimaud (@GrimaudLaurence) and McGarrigle (@McGarrigleGroup). Looking forward to welcome you and talk about chemistry!
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#EurJOC Recent Development of DNA-based Biohybrid Systems Driven by Light (Michael Smietana and co-workers) @Smietana_M @OBasle @Chembionac •
chemistry-europe.onlinelibrary.wiley.com
Merging the fields of photochemistry and DNA-based materials paved the way for unprecedented reactivities and applications. This review focuses on recent developments around the design of biohybrid...
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Recent Development of DNA‐based Biohybrid Systems Driven by Light 👉 https://t.co/mxeVBq4oa6
@OBasle @CanacYves @PastorelZachary @ChemBioNAC @umontpellier @IBMM_Balard
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🔗 Jean-Yves Winum : pur produit local à l’aura globale 👇
umontpellier.fr
Professeur à l’Institut des biomolécules Max Mousseron de l’UM, le chimiste Jean-Yves Winum conçoit et synthétise des inhibiteurs enzymatiques des anhydrases carboniques, une cible intéressante pour...
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🏆 @JeanyvesWinum, Professeur @IBMM_Balard, conçoit & synthétise des inhibiteurs enzymatiques des anhydrases carboniques, cible intéressante pour des traitements anti-cancéreux & contre différents pathogènes. Une carrière récompensée par le prix Michel Delalande @AcadPharma 👏
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Très honoré d’être lauréat du Prix Michel Delalande 2024 décerné par @AcadPharma Ce prix récompense plus de 20 ans de recherche dans le domaine de la chimie thérapeutique sur les inhibiteurs de l’anhydrase carboniques. @umontpellier @FacsciencesUM @IBMM_Balard @ChemBioNAC
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Zach (aka @PastorelZachary) has successfully defended his PhD thesis on DNA-based asymmetric catalysis. Congrats Zach ! Many thanks to the committee members @BorisVauzeilles @marinedem7 @samilakhdar1 @OBasle
@ChemBioNAC @umontpellier
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Open position : Junior Professorship in Chemical Biology / RNA chemistry Please DM for more details. @CNRSchimie
@umontpellier
@IBMM_Balard
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📣 Master 2 internship in #ChemBioNAC team at IBMM in Université de Montpellier Starting from january / february 2025. website : https://t.co/6H0S81FLWJ
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