BrumerLab
@BrumerLab
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Our group at the @ubcmsl is focused on fundamental and applied carbohydrate enzymology.
Vancouver, British Columbia
Joined September 2019
Fun having our research with @FilipPetegem on gut bacteria featured live today on The Evan Bray Show on CKOM, Saskatoon. The @CanLightSource at @Usask continues to be an invaluable resource for Canadian science. @ubcmsl @UBCChem @UBCbiochemistry
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Nice to have this collaborative work with @FilipPetegem showcased by the @CanLightSource.
Research by @UBC team on bacterium common in gut of people who eat a plant-rich diet could lead to development of helpful probiotics https://t.co/rCWdbp5X21
@mslubc @UBCBotany @UBCbiochemistry @UBCChem @ubcmsl @SSRLnews @BrumerLab @ubcchem
#guthealth #probiotics
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How eating your oatmeal feeds your #humangutmicrobiome (#Prevotella, #Segatella). Great job by @LorizollaRosa, Benedikt, and the rest of the team @ubcmsl. Thanks also to crystallography guru @FilipPetegem & quality peer-review @jbiolchem.:
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Join us next week to hear from the next invited speaker in our MSL seminar series, Dr. Eric Martens! April 17: 3-4pm MSL lecture theatre (room 102) & Zoom Hosted by: Dr. Harry Brumer (@BrumerLab) Event details: https://t.co/6QYK4yhmnn
@UBCMicroImmuno
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Lots of mentors got a call out in the article but I want to specifically highlight the support from @nkoropatkin @EricCMartens1 @SandkvistMaria @teresa_omeara @MattHFoley @RGlowacki13 and all Koropatkin and Martens lab members that made me think of myself as a microbiologist!
Rebecca Pollet, Ph.D., (@rmpollet) highlights the importance of making connections, not just between the lab and the “real” world, but also with scientists one can identify with—and helping others to do the same. Read the Spotlight: https://t.co/TPVxjXnWlF
#NAHM2023
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Check out this special issue on #CAZymes in Biologia, spearheaded by @Stefan_Janecek, with commentary by Stefan, @BHenrissat (@CAZyDB), and myself:
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Bert & his team called this a pedal bin mechanism... because of the SusD lid opening and closing - as Simon Newstead (@inwardopen) said in @JBR_White's viva "It's more like a flushing toilet!" @Nature
https://t.co/4iJ8Rp5VOZ
@AstburyCentre @nubiosciences @wellcometrust
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Great to see another favorite @CAZyDB family, GH31, getting the subfamily treatment, also using @ahvdk 's excellent tool, SSNpipe. Kudos to @sjwill99, @NicolasTerrapon, @ethangbaus, and team. #SequenceSimilarityNetworks
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Applications OPEN for a great conference! Carbohydrate-Active Enzymes for Glycan Conversions https://t.co/qAAqR1TNfR Lots of opportunities for talks from grad students and postdocs! Don't forget to apply to the associated GRC as well!
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Yay! The last installment of Hila's endo-glucanase 16 work is out in @PlantDirectJ. Great collab. w/ the Mansfield, Samuels, and Pauly labs. @ubcmsl @ubcforestry @UBCBotany @HHU_de Long story short: We still don't really know what these enzymes do in vivo!
onlinelibrary.wiley.com
The hemicelluloses comprise a group of matrix glycans that interact with cellulose microfibrils in plant cell walls and play important roles in establishing wall architecture. The structures of...
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#enzyme_engineering on Fungal Copper Radical Oxidases Work led by @LafondMichael3 @RKoncitikova in collab with @BrumerLab @VictorGuallar FEBS Press https://t.co/t9xGHWSvjI
#ANR @BBF_lab @univamu @INRAE_TRANSFORM @_3BCAR
febs.onlinelibrary.wiley.com
Fungal copper radical oxidases (CROs) from the AA5_2 subfamily can oxidize a wide panel of natural compounds including galactose-containing saccharides or primary alcohols, but the molecular determ...
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#PR_INRAE🧐A pathogenic fungus which smells of lemon? 🍄🍋This unlikely duo is the basis for a major discovery on the toxicity of a crop pest #agroecology ▶️ https://t.co/1Iac8uF5i9
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Never heard of Copper Radical Oxidases before? Check out our new review from @ubcmsl in #EssaysinBiochemistry (@PPPublishing) as a primer. These enzymes have a deep biochemical/mechanistic history and newfound roles in fungal, bacterial, & plant biology:
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Our new paper is out! 植物病原糸状菌の形態形成と感染適応戦略 : Science Advances 2022 https://t.co/OYAm93tmCx
blog.livedoor.jp
最新の論文です！Science Advances (2022)に掲載されました。"Tandem metalloenzymes gate plant cell entry by pathogenic fungi"http://www.science.org/doi/10.1126/sciadv.ade9982 Bastien Bissaro†, Sayo Kodama†, Takumi...
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How can we protect food crops from #fungal diseases? Researchers including @jgberrin and @KbYasuyuki have identified a pair of enzymes that primes fungal pathogens for plant infection that could open new avenues for preventing disease and protecting crops. https://t.co/2icLn691ra
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Proud to be part of this stellar work led by our colleagues @BBF_lab (@jgberrin, @LafondMichael3, @BastienBissaro) and @KbYasuyuki on the critical role of a Copper Radical Oxidase/Peroxidase enzyme pair in fungal phytopathogenesis.
Hot-of-the press !! Excited to share our last study, in which we reveal a new plant infection mechanism involving fungal metalloenzymes! (1/n) @INRAE_France @INRAE_TRANSFORM @INRAE_PACA
@univAMU_Europe
https://t.co/E5cDdItEyr
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Recently published work 👇by us @BBF_lab together with @BrumerLab for those interested in characterizing/dectecting galactose oxydase activity ! Special Thanks to first authors Eden Kaddouch and Maria Cleveland ! @INRAE_Intl @INRAE_PACA @_3BCAR @ubcmsl
https://t.co/giIfkfNlTi
pubs.rsc.org
Galactose oxidase (GalOx, EC.1.1.3.9) is one of the most extensively studied copper radical oxidases (CROs). The reaction catalyzed by GalOx leads to the oxidation of the C-6 hydroxyl group of...
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A nice way to end the week: Yann & @MClevelandPhD's capstone paper from their time in the lab is out today in @ACSCatalysis. Yann's original vision plus a little scientific serendipity made this a pretty cool story. @ubcmsl @ubcchem @UBCBioProducts
pubs.acs.org
Copper radical oxidases (CROs) from Auxiliary Activity Family 5, Subfamily 2 (AA5_2), are organic cofactor-free biocatalysts for the selective oxidation of alcohols to the corresponding aldehydes....
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Lead researcher Matthias Kretschmer & team from the @KronstadLab & @BrumerLab are cracking the code for a cure to “corn smut” (Ustilago maydis). 🌽🔬 Learn more about their groundbreaking research and recent publication in @ScienceMagazine: https://t.co/jYAyA9AVXJ
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