How exercise can protect against Alzheimer’s.

RT @bertogliolab: Disinhibition of the VTA after trauma restores REM sleep disturbances and reduces long-term behavioral indices of fear me….

Machine learning revealed proliferating neural progenitor cells in the adolescent and adult human hippocampus—similar to those in mice and pigs—supporting the existence of adult neurogenesis and offering key insights for brain science and medicine.

Nerve terminals tap into lipid droplets during electrical activity to fuel metabolism—highlighting a key role for these droplets in sustaining neuron function in vivo. #Neuroscience #BrainEnergy.

RT @MolNeuro: Methylome analysis of #FTLD patients with #TDP43 pathology identifies #epigenetic signatures specific to pathological subtype….

vCA1 neurons encode both identity and traits of familiar individuals. Some fire for specific sex/strain (“social property cells”), others for unique combos (“social identity cells”)—via firing rate & spike timing tied to hippocampal theta rhythm.

RT @MacrinePhD: Cognition isn't abstract—it's embodied. Sensory-motor adaptations are intrinsic to cognitive evolution, not confounding var….

Esketamine shows promise as a standalone treatment for treatment-resistant depression, especially in patients who don’t respond to or can’t tolerate oral antidepressants. #Depression #Esketamine #MentalHealth.

RT @braincomms: Gonzalez-Ortiz et al. report plasma p-tau217 measurement in newborns; levels are significantly higher in healthy newborns t….

Brain–computer interfaces being trialled in China offer some advantages over Neuralink and other leading US devices.

RT @ttwang0908: Thrilled to share that my first REVIEW is online @NatRevNeurosci today! We highlighted the molecular and functional diversi….

RT @AllenInstitute: The fireworks in your mind. 🧠✨ This sparkling video shows the neurotransmitter glutamate being released into synapses,….

When cognitively fatigued, people tend to avoid high-effort rewards. Dorsolateral prefrontal cortex signals cognitive strain, which alters effort valuation in the insula—shaping decisions under fatigue. #Neuroscience #CognitiveFatigue #DecisionMaking.

RT @Maitreyee_W: Check out the new @Nature Research Briefings article “Brain implant decodes neural activity to produce expressive speech”….

New research reveals how the dlPFC and frontoparietal network drive learning. GABA and brain connectivity shape who benefits most from brain-based interventions—especially those with less optimal learning profiles. #Neuroscience #Education #GABA.

RT @NatMetabolism: Triglycerides are an important fuel reserve for synapse function in the brain

RT @JAMAPsych: Individuals with cannabis use disorder showed elevated midbrain dopamine function, potentially linking cannabis use to an in….

Breaking down neuronal glycogen reduces tau pathology in FTLD-tau models by shifting glucose to the pentose phosphate pathway and easing oxidative stress—highlighting a key neuroprotective role of dietary restriction. #neuroscience #tauopathy #FTLD.

RT @NeuroCellPress: Online now: Distinct dendritic integration strategies control dynamics of inhibition in the neocortex .

Exercise alters gene expression differently in wild-type vs. Alzheimer's mice, especially in immature neurons. It partially restores AD-related gene changes and boosts a key neurovascular astrocyte subtype reduced in AD. #Alzheimers #Neuroscience #Exercise.