Steffy B Manjila
@BManjila
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Assistant Professor @LSUHealthNO interested in Neuroanatomy
New Orleans, LA
Joined November 2015
Loss of the calcium sensor #STIM2, but not of STIM1, worsens #ColorectalCancer growth and metastasis by boosting calcium ion content in the endoplasmic reticulum, remodeling mitochondria, and rewiring transcriptional activity. @TrebakM @Trayambak_P
https://t.co/DF0DZu5Jza
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Our first attempt to understand the dorsal endopiriform nucleus (EPd)- connectivity and functions- now published in Cell Reports. A huge thanks to Dr. Yongsoo Kim @yongsookimlab and all other lab members and colleagues who made this happen!
Brain-wide connectivity and novelty response of the dorsal endopiriform nucleus in mice
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Excited to announce our NIH RM1 grant, investigating impact of ~100 neurodevelopmental disorder risk genes using mice as an animal model.
psu.edu
Illuminating key biological pathways that underlie neurodevelopmental and psychiatric disorders, such as autism spectrum disorder and attention deficit hyperactivity disorder, is the goal of a new...
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Our first attempt to understand the anatomy and function of the dorsal endopiriform as a part of the claustrum complex, by @BManjila and others.
biorxiv.org
The dorsal endopiriform nucleus (EPd) is an enigmatic cortical subplate structure located inside the piriform cortex that shares a similar developmental origin with the claustrum. Although the EPd...
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Aging vessel mapping paper is officially out. https://t.co/BDj43YTiv9 We examined structural and functional changes of cerebrovasculature and found brain region specific changes in normally aging C57 mice compared to young mice.
nature.com
Nature Communications - We have limited knowledge of how aging affects brain vascular structure and function. Here, the authors show that aging induces selective reduction of vasculature and...
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We're recruiting postdocs/researchers/lab manager/technicians, doing high-resolution whole brain mapping, atlasing, neural recording, behavioral tracking, vascular mapping, etc. https://t.co/LZG0ofKFvj,
indeed.com
Penn State University College of Medicine
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🔮Ever wished you could just say what behavioral analysis you wanted? ... "Plot the animal's trajectory" "Count the head hips in the open arm" 👀🪄we present AmadeusGPT🎻 to do this ... 🗞@shaokaiyeah @jessy_lauer @zhoumu53 @trackingplumes and me https://t.co/PAazDd3iXj 🧵⬇️
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Reminds me our surprising 1996 discovery that Oxt KO mice show ~normal maternal behavior, but many studies show a role for Oxt in MB in mice that develop with Oxt (WT) like @Froemkelab excellent papers. Congrats to @LabManoli @NiraoShah 👇 https://t.co/8rqy4uof6k
pubmed.ncbi.nlm.nih.gov
Oxytocin, a neurohypophyseal hormone, has been traditionally considered essential for mammalian reproduction. In addition to uterine contractions during labor and milk ejection during nursing,...
Voles lacking oxytocin receptor still pair-bond, lactate & tend pups 🤯 Paywalled Neuron paper but nice discussion here including @lyoun03
https://t.co/SYgw6ZYCbs
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Super excited to share our new @STARProtocols paper on how to use serial two-photon tomography to quantitatively map cell types and the cerebrovasculature in the entire mouse brain! Thank you @yongsookimlab for my first first-author publication! 🎉 https://t.co/Pn3Fbh8FwA
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Serial two-photon tomography has been a key tool for our cell type and cerebrovascular mapping in mouse brains. Here is a detailed protocol from sample processing to data analysis. https://t.co/kjzs6IBU8E by @josephineliwang @HannahCBennett7.
star-protocols.cell.com
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all...
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Congratulations Dr. Bennett! I'm so happy for you!
Proudly present Dr. Hannah Bennett who successfully defended her thesis yesterday!
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I’m having a wonderful time at #SfN22 in person this year! Tomorrow afternoon I will present my poster highlighting regional vulnerability and anatomical remodeling of the pericyte and vascular network in the aging mouse brain! Please stop by C61 from 3-4pm PST! 🧠🫀
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Excited to be in San Diego for Neuroscience 2022 #SfN2022 @SfNtweets. I'll be presenting a poster on Monday, November 14th from 8am-9am (Board no. WW7, #320.13). Please stop by the poster to learn about anatomy and functions of the Endopiriform Nucleus (EPd)!
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We’re all here for #SfN22! 😎🧠 Quick shoutout: Come find us & our posters if you’re interested in developmental cell type mapping & 🐭 brain atlasing (myself + @FaeKronman), pericyte & vascular mapping in aging (@HannahCBennett7), and EPd cortex anatomy & function (@BManjila)!
The whole kim lab team is at #SfN2022. The great first night with some awesome hotpot dinner with Lydia @2queues as our special guest.
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Excited to be heading to San Diego for #SfN22 @SfNtweets ☀️ I’ll be presenting a poster on Mon, Nov. 14th from 2-3pm (Session 350, #350.02)! And sharing about how we’re mapping inhibitory cell types & microglia during development using cellular resolution microscopy!🔬
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excited to wear around this pin featuring our new @yongsookimlab logo during SfN, which is two weekends away! 😎
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When we published the oxytocin wiring diagram paper earlier this year, I thought we almost need another paper to actually explain 9 circuits with oxytocin connection in more details. Here it is! https://t.co/KDjIwFCPGs, by @BManjila
frontiersin.org
The hypothalamic neuropeptide, oxytocin (Oxt), has been the focus of research for decades due to its effects on body physiology, neural circuits, and various...
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#JNeurosci: Using high-resolution 3D mapping methods in adult mice, Son et al. @yongsookimlab @penn_state found Oxytocin connections with 9 functional brain circuits controlling cognition, brain state, & somatic visceral response. https://t.co/GSYzXCC2Hk
jneurosci.org
Oxytocin (Oxt) neurons regulate diverse physiological responses via direct connections with different neural circuits. However, the lack of comprehensive input-output wiring diagrams of Oxt neurons...
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Today's #FluorescenceFriday comes from @yongsookimlab: oxytocin (magenta) and vasopressin (green) in mouse brain, imaged with #SmartSPIM. To learn more about his #neuroscience research, check out the interview on our blog!
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#JNeurosci: Using high-resolution 3D mapping methods in adult mice, Son et al. @yongsookimlab @penn_state found Oxytocin connections with 9 functional brain circuits controlling cognition, brain state, & somatic visceral response. https://t.co/MYb4AVcdLa
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