🔥 Hot off the press: In a new @Nature study, @ErnstLengyel and team show that blocking NNMT in tumor-supporting cells restores immune response & stops ovarian cancer growth, offering a new strategy for hard to treat cancers. @OvCa_UChicago @uchicago_obgyn https://t.co/h05za6qlG5

📢 New in Cancer Cell: Radiotherapy is essential for local control—but can it unintentionally accelerate growth of distant metastases? We examine how RT-induced EGFR signaling and immune modulation may fuel metastatic progression. 🧠🧬🔬 Read: https://t.co/gCAjDKMcIb

Kudos to @rweichselbaum and colleagues on publishing an excellent article in @jclinicalinvest demonstrating enhanced antitumor immunity with inhibition/deletion of m6A reader YTHDF1. @UCCancerCenter @UChicagoRadonc @UChiChemistry @Ludwig_Cancer https://t.co/L3obPaLBPM

.@LiangWang917847 @ConnorLynchMD @SeanPitroda @AndrasPiffko @KTyyqx @rweichselbaum et al @UChicagoMed @Ludwig_Cancer review the immune response to #radiotherapy-induced anti-tumor effects, & the combination of immune checkpoint blockade w/ radiotherapy https://t.co/cVzftL6SPI

A neural #epigenetic signature detectable via plasma analyses is prognostic in patients with #glioblastoma (#GBM) resembling an oligodendrocyte-precursor and neuronal-precursor cell-like state and showing increased neuro-to-glioma synapse formation. #NPC https://t.co/8vIcB8xKS6

🔥 Hot off the press: @UCCancerCenter researchers Liangliang Wang, PhD, @rweichselbaum, Chuan He, PhD, and colleagues published an excellent paper in @jclinicalinvest showing the rescue of #RadiationResistance with increased levels of #BAMBI in myeloid cells. @UChicagoRadonc

TGF-β pseudoreceptor BAMBI imrpoves antitumor effects by Radiation...potential clinical translation! https://t.co/YZAKMHb6SD Thanks Dr. Weichselbaum @rweichselbaum

Blocking a key immune protein improves radiation therapy for cancer | Biological Sciences Division | The University of Chicago

Online Now: YTHDF2 inhibition potentiates radiotherapy antitumor efficacy

Nanotech devised by Ludwig @UChicagoMed's Wenbin Lin, Kaiting Yang, Ralph Weichselbaum & team triggers immune responses against multiple cancers in mice. Combined with radio- or immunotherapy, it extends survival in models of pancreatic & brain cancer. https://t.co/iArlzdzUao

New content online: Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration https://t.co/GCBBqgdc6t

New research: Clinical determinants impacting overall survival of patients with operable brain metastases from non-small cell lung cancer: Non-small cell lung cancer (NSCLC) is currently the leading cause of cancer-related death worldwide, and… https://t.co/2DVHyaWPNd #oncology