Arun John Peter
@ATJohnPeter
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Assistant Professor, University of British Columbia @UBCcps @ubclifesciences | Lipid trafficking, membrane contact sites & organelle homeostasis
Joined August 2021
I am happy to share that I've begun my new role as an Assistant Professor @UBC in the Department of Cellular and Physiological Sciences @UBCcps @ubclifesciences The lab will explore the mechanisms of lipid transport and lipid quality control in organelles 1/4.
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RT @ShadySaad: It is finally out! I am incredibly proud to share that my work has officially been published in Cell @CellCellPress!.This w….
cell.com
DNA binding and phosphorylation protect FOXP2, a transcription factor with the longest polyQ track in the proteome, from aggregation during interphase and mitosis. Harnessing these native solubilit...
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RT @MartinPacesa: Have you ever wanted to design protein binders with ease? Today we present 𝑩𝒊𝒏𝒅𝑪𝒓𝒂𝒇𝒕, a user-friendly and open-source pip….
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Last but not least, a big thank you to all my new colleagues @UBCcps @ubclifesciences for their support & for throwing an amazing welcome party :) Looking forward to exciting science and good times ahead! 4/4.
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Special thanks to all the colleagues, friends and well-wishers for their support, advice and feedback @LabBarral @GabrielNeurohr @KukulskiWanda @FlyJagannathan @KarstenWeisLab 3/4.
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I am very grateful for the constant support from my PhD and Postdoc supervisors @UngermannLab @KornmannLab This journey would not have been possible without the generous support and guidance of @PeterLab8 @LabVanni 2/4.
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RT @LabVanni: 2. The work from @sriraksha616, @dani_alv4 and @ATJohnPeter on identifying lipid binding pocket for lipid transport proteins….
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Here is our short review on METALIC and its potential to understand lipid traffic in vivo.
febs.onlinelibrary.wiley.com
Lipid transport is an essential process that underlies the biogenesis and expansion of organelles. Despite its basic importance, there is a dearth of assays to probe lipid exchange between organell...
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RT @sandhya_manohar: Ever wonder why cells of the same type tend to have a pretty uniform size? Check out our new paper out in @MolecularCe….
cell.com
Manohar et al. studied how increased cell size—a hallmark of senescence—impairs long-term proliferation. Excess cell size activates p53-p21 signaling and impairs 53BP1 recruitment to DNA double-str...
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This beautiful study caught different lipid transfer proteins in the act, revealing striking similarities in their mode of action!.
Thrilled to share the latest preprint from the lab! This was a MD simulation tour-de-force from @sriraksha616 and @AndreaDiLuca7, probably the most MD data-rich study in my career. If you are interested in lipid transport and homeostasis follow along! A #lipidtime 🧵: (1/9).
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Cool new strategy to visualize PM-ER lipid traffic!.
We (Dongjun Liang and Lin Luan) harness chemoenzymatic tagging & super-fast #bioorthogonal chemistry to make fluorescent lipids that report on PM-to-ER phospholipid flux mediated by a dedicated family of lipid transfer proteins at these contact sites! 2/2
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When too many cooks rock the broth!.
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RT @Rainmaker1973: You can make a glass sing with your fingers, but can you play Sugar Plum Fairy by Tchaikovsky? The Glass Duo did it, amo….
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RT @biorxiv_cellbio: A membrane sensing mechanism couples local lipid metabolism to protein degradation at the inner nuclear membrane http….
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RT @AyelenGonzalezM: I am super happy to share that the first paper of our lab is out in @JcellBiol!!! “Cvm1 is a component of multiple vac….
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In this Article Commentary in @ContactCTC, we think aloud on how the conserved bridge-like lipid transport protein Csf1 is involved in lipid remodeling and homeoviscous adaptation @YaanJang @BenoitKornmann
journals.sagepub.com
The non-vesicular transport of lipids between organelles mediated by lipid transport proteins (LTPs) is a key determinant of organelle biogenesis and function. ...
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RT @OlzmannLab: This is so cool!! METALIC (Mass tagging-Enabled TrAcking of Lipids In Cells), a method to track interorganelle lipid flux i….
nature.com
Nature Cell Biology - John Peter et al. develop METALIC (Mass tagging-Enabled TrAcking of Lipids In Cells), an approach to track interorganelle lipid flux in live cells using organelle-targeted...
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Our study demonstrating a new versatile strategy to monitor lipid transport in vivo is out in Nature Cell Biology @PeterLab8 @BenoitKornmann @KornmannLab .Big thanks to @LabVanni for great support during the completion of this work!.
nature.com
Nature Cell Biology - John Peter et al. develop METALIC (Mass tagging-Enabled TrAcking of Lipids In Cells), an approach to track interorganelle lipid flux in live cells using organelle-targeted...
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