Andrew Holland
@AHollandLab
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Director @AmgenOncology, ❤️ @JohnsHopkinsMBG
Thousand Oaks, CA
Joined August 2018
Interested in E3-Ub ligase regulation? Check out the latest paper from our lab: Big congrats to @PeterYeowZY who conceived and drove this study!.
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RT @JCellBiol: Centriole structural integrity defects are a crucial feature of hydrolethalus syndrome, say Ana Curinha (@ana_curinha), Andr….
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Check out our latest work using the AID2 system to control the levels of an essential protein in mice. Congrats to the entire team, especially @SladkyValentina and Margaret Strong.
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Check out our latest paper in @JCellBiol. Congrats to the entire team, especially @ana_curinha.
HLS, an autosomal recessive #ciliopathy, is associated with a mutation in the centriole protein HYLS1. Curinha, Holland et al @JohnsHopkins show that HYLS1 mutant mice exhibit developmental abnormalities, with #centriole integrity & #cilia assembly defects
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RT @madamscientist: BREAKING: Johns Hopkins along with 12 peer institutions and Assoc of Amer Univ sues to stop drastic cuts in NIH funding….
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Three papers accepted in one week. That won’t ever happen again….
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RT @EChenLab: Curious about how cells generate mechanically stiff invasive protrusions from branched actin filaments? Check out our paper p….
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RT @PeterYeowZY: 📝Preprint! 1️⃣Question: How are large MTOC structures regulated by an E3 ligase? 🧵In 2020, we showed TRIM37 suppresses sur….
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RT @PeterYeowZY: 2️⃣ Model: My work at @ahollandlab suggests a shared blueprint within the TRIM family for assembly regulation. Akin to TRI….
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RT @jaybradner: Today's @US_FDA decision to expand use of Bispecific T-cell Engager (BiTE®) immunotherapy to adult patients receiving front….
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RT @jaybradner: Today’s @US_FDA approval is a landmark achievement in the evolution of small cell lung cancer care - demonstrating @Amgen’….
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Congrats Sergi, Connor and team!.
Connor's paper is out in Science! Thanks to all the present and former lab members for making this possible. If you are interested in the mechanisms behind stress induced endocycling or the role of CDK4/6 in maintaining G2 arrest, check it out:.
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RT @AHollandLab: We are recruiting for a postdoc to join our group at Amgen Oncology in Thousand Oaks, California. This is a great opportun….
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