Zied Gaieb
@zied_gaieb
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Joined March 2020
In our new study out in @NatureComms, co-led by @xandra_nuqui and myself, in collab. w/ @McLellan_Lab & @ChandranLab, we designed a 2W-stabilized SARS-CoV-2 S2 antigen exhibiting enhanced expression and preserved immunogenicity against sarbecoviruses. 👉 https://t.co/gbGlXSOwyM
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Meta just dropped 600+ million protein structure predictions, made using a large language model. My latest for @Nature
https://t.co/HESpOVH9hw 1/3
nature.com
Nature - Microbial molecules from soil, seawater and human bodies are among the planet’s least understood.
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🚨 Our new #SARSCoV2 preprint shows how spike protein charge drives variant adaptation & function #Omicron has a “bulls-eye” charge pattern that leads to faster, stronger & more synergistic binding to cell surface glycans & ACE2 #glycotime #compchem
https://t.co/fw0QBRXCwH
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🚨Happy to share our newest labor of (nerd) love 🤓❤️ In situ dynamics of influenza glycoproteins illuminate their vulnerabilities w/ @kanekiyom @LCasalino88 @chem_christian, J Lederhofer, Y Tsybovsky, I Wilson #glycotime #compchem
https://t.co/WiBMdthQz4 🧵:
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Cat's out of the bag, we're in @Nature !!! 🎊🎉🤯 A potpourri of phage fun! Tweetorials below...
nature.com
Nature - The nucleus-like compartment formed in bacteria during infection by jumbo phage 201phi2-1 is composed of the bacteriophage protein chimallin, which can self-assemble into closed...
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Thrilled and honored to see my artwork on the cover of such an important book for #glycobiology. Can't wait to have a physical copy in my hands! Thanks to all the Authors for the support. https://t.co/pNLSfYuVWl
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Just gave my 50th -- and final -- lecture on our work in #SARSCoV2 for 2021. Reflecting on how GRATEFUL I am to all the amazing team members who made it possible. (Yes, 4 Acknowledgment slides worth of gratitude!) ♥️🤓
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Introducing the @ACSCentSci Examples of the Exceptional #COVID19 Special Collection; an inspiring showcase of research articles, Outlooks, news features, and more. An emblem of modern science and a time capsule for our extraordinary times. Read now: https://t.co/52tM4yCq5J
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Honored to see #BeyondShielding on the cover of this exceptional @ACSCentSci #COVID19 special collection. Check it out! #glycotime
@zied_gaieb @McLellan_Lab @ElisaTelisa @RommieAmaro
Introducing the @ACSCentSci Examples of the Exceptional #COVID19 Special Collection; an inspiring showcase of research articles, Outlooks, news features, and more. An emblem of modern science and a time capsule for our extraordinary times. Read now: https://t.co/52tM4yCq5J
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Check out 👀 our #COVIDisAirborne preprint w/ tech aspects of our billion-atom simulation of Delta #SARSCoV2 in a respiratory aerosol, multiscale sims of spike opening @ltchong @arvindr_, pH @AdrianMulholla1 & calcium effects @tfmiller3 @EntosAI
https://t.co/sy1pkoTyvg
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I'm just gonna leave this here for now. More next week @Supercomputing Sound on. #COVIDisAirborne
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AlphaFold for RNA? Excited to share our @StanfordAILab work on deep learning for predicting 3D RNA structure, out today on the cover of @ScienceMagazine! https://t.co/5T9rzHmRP2 Sound interesting? Join us at https://t.co/6Yv5OUqGoX to bring this work to life! More news soon!
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Outstanding @Nature feature by @Scudellari unraveling scientists' efforts to decipher SARS-CoV-2. Thanks for including @RommieAmaro's lab contribution and my rendering of our glycosylated spike model (w/ @nikinks sleek graphics) https://t.co/xfHqqO65WW
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Today we released a preprint https://t.co/pm7lPCpyZm where we take a step towards the next challenge: building a nanopore single-molecule PROTEIN sequencer! 😳 Awesome experiments by postdoc Henry Brinkerhoff of our #CDlab, augmented with MD simulations of @aksimentievLab 1/x
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Animation Lab postdoc Shraddha @Na_y_ak is very excited to release "The Journey of a Metabolite," a lesson on metabolic flux for undergrads: https://t.co/DPugM6F7fo The gif below shows a glimpse of carbon flux through glycolysis (click the link to see the rest and much more!)
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Thank you for sharing Lorenzo! It was definitely one of my most exciting projects. It’s crazy how much progress we all made in such a short amount of time. Ps Our artwork has seen better days lol
I went back to the lab today, and on the whiteboard I found some preliminary sketches from March 2020 where I and @zied_gaieb were trying to figure out the SARS-CoV-2 spike. I still can't believe how much work has been done and how much we know now that we did not back then.
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A profile of our ❄️🐉 collaboration between @MITBiology @MIT_CSAIL @MITMath Solve is a little strong 😅 but proud to contribute to a truly interdisciplinary problem with @tbepler1 @jhdavislab and @lab_berger
Grad student @ZhongingAlong reached across departmental lines to solve a long-standing problem in electron microscopy. Co-advised by @jhdavislab and @lab_berger, she helped devise software to reconstruct molecules in motion. Article by @saimamaysidik: https://t.co/kaRi70Mu1M
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Behind the Gordon Bell Prize-Winning Spike Protein Simulations https://t.co/9ZKQq0hfIv
#HPC #COVID19
hpcwire.com
Four months ago, Rommie Amaro and her colleagues were accepting the first-ever Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research. At the time, cases were slowly ramping...
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