Yuval Shapir Itai
@yuval_shap
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Post-doc at @dahanlab, WIS. Antibody mediated immunity and immunotherapy.
Weizmann Institute of Science
Joined October 2020
I'm very excited to share my PhD work and first first-author paper. Meet BiCE, our bispecific DC-T cell engager designed to potentiate aPD-1 immunotherapy, published today in @CellCellPress. Big thanks to my mentor @DahanLab and our collaborators @orenbarboy and @IdoAmitLabโด๏ธ
Together with @IdoAmitLab weโre very excited to introduce BiCE (Bispecific DC-T Cell Engager)- a new platform to engineer immune cell communication for #cancer #immunotherapy. Led by the amazing @yuval_shap @orenbarboy, now out @CellCellPress: https://t.co/COVWAN7Tbf (1/11)
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Check out this beautiful story championed by @FadiSheban of the @IdoAmitLab, published today in @Cancer_Cell ๐ @FadiSheban, thanks for bringing me in to be a small part of the team, the best scientific discussions and the coffee โ๏ธ
We are excited to share our new study @Cancer_Cell identifying Zeb2 as a master genetic switch controlling the tumor-associated macrophage (TAM) program. Led by @FadiSheban, @TgSanPhan, @CuriousKX & @FlorianIngelfi1. (1/20) https://t.co/ZpPXUjbwRF
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Excited to see our BiCE highlighted as an emerging strategy to enhance cDC1-mediated cross-priming ๐คฉ @DahanLab @IdoAmitLab
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Had a great time presenting our work and hearing about exciting new science at the 3rd @ImmunoSens - IFReC International School on Advanced Immunology in Japan. Thanks for the amazing opportunity ๐๐ผ @DahanLab
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Online now: Protocol for assessing murine cell doublet engagement and subsequent effects using flow cytometry and imaging flow cytometry https://t.co/YleWGmHp44
#protocol #starprotocols #cellpress
star-protocols.cell.com
STAR Protocols is an open access, peer-reviewed journal from Cell Press. We offer structured, transparent, accessible, and repeatable step-by-step experimental and computational protocols from all...
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Link to our BiCE paper published in @CellCellPress
https://t.co/8cqOCX1qr5
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If youโre interested in our protocols for cell doublet quantification and imagestream analysis from our #BiCE paper, or if you have a bispecific engager of your own that youโd like to test, check out our new protocol from @DahanLab with @PoratZiv published in @STARProtocols ๐ซง
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Congratulations to Yuval Shapir of the Systems Immunology Department (from the group of Dr. Rony Dahan) for being awarded the EPHAR-EACPT Young Investigator Awards @yuval_shap
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Excited to share that Iโve been awarded the EACPT-EPHAR Young Investigator Award in Translational Pharmacology, and the opportunity to present our work here in Rotterdam. Thank you to @EACPT, @DahanLab and our collaborators ๐๐ผ
Outstanding award presentation by @yuval_shap while receiving the EPHAR-EACPT Young Investigator Award in Translational Pharmacology. Congrats Yuval, we are very proud of you ๐๐ป ๐ @EACPT
@Sys_Immunology
@WeizmannScience
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I am honored to receive the 2024 Rappaport Prize in Biomedical Sciences for the development of new cancer immunotherapies. A big thank you to my mentor and PI, @DahanLab, my amazing labmates and collaborators, @WeizmannScience , and the @Sys_Immunology department ๐
Congratulations to @yuval_shap (from the group of Dr. Rony Dahan) upon being awarded the 2024 Rappaport Prize for an outstanding doctoral student for excellence in the field of Biomedical Research
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Congrats @orenbarboy, Akhiad and teams! Happy to see this out, and always happy to collaborate โจ
We are proud to share our latest work, in collaboration with Amos Tanay lab, presenting a framework for in vivo tracking of CD8+ T cells' response to immunotherapy over time & at single-cell resolution, led by @orenbarboy and Akhiad Bercovich. https://t.co/Fmt4GoDEok. (1/19)
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Honored to receive the 2024 Rappaport Prize in Biomedical Sciences for the development of new cancer immunotherapies. A big thank you to my mentor and PI Rony @DahanLab , @Sys_Immunology @WeizmannScience for making my science dreams a reality.
2/3 โฆResearch, for her groundbreaking discoveries in proteostasis and protein degradation regulation and their important ramifications on human disease. Huge Kudos Yifat! And to make us even prouder, Yuval Shapir @yuval_shap of @DahanLab has been awarded the 2024 Rappaportโฆ
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Read this week's Cancer Discovery #ResearchWatch: A Bispecific Dendritic #Tcell Engager Induces Potent Antitumor Immunity, a summary of the paper by @yuval_shap, @orenbarboy, @IdoAmitLab, @DahanLab et al. https://t.co/msfTt2K5Fl
@WeizmannScience
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Thank you for highlighting our work! โ๏ธ @NatRevDrugDisc @DahanLab @IdoAmitLab
https://t.co/MaGxFU8AKh
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A new cancer #immunotherapy approach uses a bispecific antibody to bring #Tcells and #dendriticcells together. Antibody-treated mice show enhanced immune reprogramming, both in tumors and in tumor-draining lymph nodes. @DahanLab @IdoAmitLab
https://t.co/2CWWQvXLJv
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In the latest issue! Bispecific dendritic-T cell engager potentiates anti-tumor immunity
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๐We had a blast working with the @DahanLab @yuval_shap to illustrate their latest paper on BiCE (Bispecific DC-T Cell Engager), a new bispecific DC-T cell engager designed to potentiate aPD-1 immunotherapy! ๐กLearn more about their amazing work:
Together with @IdoAmitLab weโre very excited to introduce BiCE (Bispecific DC-T Cell Engager)- a new platform to engineer immune cell communication for #cancer #immunotherapy. Led by the amazing @yuval_shap @orenbarboy, now out @CellCellPress: https://t.co/COVWAN7Tbf (1/11)
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In the beautiful artwork by @DrawImpacts, T-DC interactions potentiate the immune circuts necessary to illuminate the tumor microenvironment. @DahanLab @IdoAmitLab
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