Wenyun Lu
@wenyun_lu
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Great commentary on features in ESI metabolomics studies and next steps! A Perspective on Unintentional Fragments and Their Impact on the Dark Metabolome, Untargeted Profiling, Molecular Networking, Public Data, and Repository Scale Analysis | JACS Au
pubs.acs.org
In/postsource fragments (ISFs) arise during electrospray ionization or ion transfer in mass spectrometry when molecular bonds break, generating ions that can complicate data interpretation. Although...
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People being treated for certain deadly cancers lived longer if they had received an mRNA-based vaccine against COVID-19 than if they hadnโt https://t.co/ZR3tYeHElg
nature.com
Nature - mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer โ in an unexpected way.
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Nature research paper: Spatial metabolic gradients in the liver and small intestine https://t.co/QwgPMepyTt
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๐๐๐ญ ๐ญ๐ซ๐ข๐๐ค ๐๐จ๐ซ ๐๐ก๐ข๐ฅ๐๐ก๐จ๐จ๐ ๐๐๐ง๐๐๐ซ: ๐๐๐ญ๐ฎ๐ซ๐ ๐๐ซ๐ญ๐ข๐๐ฅ๐, ๐๐จ๐ฏ๐๐ซ, ๐๐ง๐ ๐ง๐๐ฐ๐ฌ ๐๐๐๐ญ๐ฎ๐ซ๐! 1) https://t.co/krtqEwQkS1 2) https://t.co/StZvIlYw0m 3) https://t.co/gY57eEyevv I couldnโt be prouder of @sarah_cherkaoui and all the co-authors!
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้ญๆฏๅคงๆญ็ง๏ผ่ฟไธชๅฐๅฅๅคชๅฎๅจไบ๏ผไธไธๅญๆญ็ง่ฟไนๅค๏ผไธ็ๅฐฑไผใ #็ๆดปๆๅทง #ๅท็ฅ่ฏ็พ็ง
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Spatial metabolic gradients in the liver and small intestine
nature.com
Nature - Mapping of spatial metabolic gradients in the mouse liver and intestine identifies fructose-induced focal derangements in liver metabolism.
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Nature research paper: Reprogramming neuroblastoma by diet-enhanced polyamine depletion https://t.co/hvdGzzAlKZ
nature.com
Nature - Enhanced polyamine depletion in neuroblastoma models decreases translation of mRNA codons with adenosine in the third position, reprogramming the tumour proteome away from cell cycle...
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Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation https://t.co/PQwWYn588X
nature.com
Nature - Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation.
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A cancer therapy targeting the interaction between metabolism & protein synthesis. Dietary restriction of arginine and proline depletes polyamines, which in turn causes ribosome stalling at codons with A in the third position. This shifts the balances towards cell ...
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Explanation in the New York Times @nytimes of our multiomics study of the human with the most #longevity: clues for promoting a #healthy and extended #lifespan; and more targeted #antiaging interventions and therapies. Story by @ginakolata
https://t.co/WCQ0mGTEtB
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๐๏ธ Just published in Nature! Excited to share our work on metabolism and translation regulation crosstalk in childhood cancer. We introduce a pro-differentiation proteome to cure! ๐ Reprogramming neuroblastoma by diet-enhanced polyamine depletion: https://t.co/krtqEwQkS1
Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation https://t.co/PQwWYn588X
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๐จ Excited to share our new paper is out in Nature! ๐ Reprogramming neuroblastoma by diet-enhanced polyamine depletion https://t.co/yftm24H0CJ
nature.com
Nature - Enhanced polyamine depletion in neuroblastoma models decreases translation of mRNA codons with adenosine in the third position, reprogramming the tumour proteome away from cell cycle...
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I recently learned that the novelist, Cormac McCarthy, spent several years at the Santa Fe Institute helping scientists write papers. His advice was condensed into a brief Nature column. The first three points, and some of the final points, are really good. (h/t @eryney_ok)
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At a defining moment, a broad coalition will come to Capitol Hill to protect science, defend progress and stand up for patients. @CancerTodayMag previews The Rally for Medical Research on Thursday, September 18. https://t.co/4yKYZma5gY
#RallyMedRes
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The Amish have a 4% obesity rate - 10x lower than Americans. They don't count calories or track macros. No gym memberships. No fitness apps. No Ozempic. Yet theyยดre leaner, healthier and happier than us. Their secret? These 8 forgotten principles: ๐งต
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