REVIEW|Aitken et al. discuss the current understanding of how #endothelial cells sense #BloodFlow focusing on #mechanosensing and #mechanotransduction molecules and mechanisms. @EllieTzima @vedanta_mehta, @RDMOxford, @TheBHF| https://t.co/Of9Y6kyMsv 👉 https://t.co/qHANMgPgTw

Joining forces with the incomparable #MartinSchwartz >20 years later to discuss #endothelial #mechanosensors across the pond. With the amazing Claire Aitken and @vedanta_mehta @HumanGeneticsOx @RDMOxford @NatureCVR @TheBHF @wellcometrust https://t.co/YDJlcAcBCc

Image shows decoupling of eukaryotic initiation factor 6 cellular functions. @ad_keen, @vedanta_mehta @karlai_pang John S. Reader, @EllieTzima and colleagues @HumanGeneticsOx show that eIF6 regulates mechanical responses in endothelial cells. https://t.co/pne5jxpfrZ #Cytoskeleton

In @JCellBiol, @ad_keen, @vedanta_mehta @karlai_pang, Reader, @EllieTzima et al. @HumanGeneticsOx discover a new role for eIF6, a protein classically known for its role in protein synthesis, in #mechanotransduction, and the cellular response to force. https://t.co/nxDXVDPCSw

.@ad_keen, @vedanta_mehta @karlai_pang, Reader, @EllieTzima et al. @HumanGeneticsOx discover a new role for eIF6, a protein classically known for its role in protein synthesis, in #mechanotransduction, and the cellular response to force. https://t.co/pne5jxpfrZ #Cytoskeleton

Thank you to our collaborators @adriohernandez and funders @BBSRC @TheBHF @wellcometrust and of course to our wonderful team Adam Keen, @vedanta_mehta, Luke Payne, @karlai_pang , Lisa Simpson and the reviewers and editors @JCellBiol. @RDMOxford @UniofOxford

Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway

A #GeneTherapy can counteract infantile parkinsonism and other hallmarks of the rare neurodegenerative disease dopamine transporter deficiency syndrome, according to new work in mice and patient-derived cells from @DrJo_Ng, @SimonWad, and co at @UCL_IfWH. https://t.co/Nqy8ZXmbr2

Thank you Caro for all your support :-)

“Rings of Fire” - Stimulating the intricate network of blood vessels to grow in a dish. Extremely delighted to see that our recent work has featured on the cover page of the American Heart Association’s monthly magazine Arteriosclerosis, Thrombosis & Vascular Biology! #UCL #BHF

Improve your customer service and efficiency #Vodafone !!! Absolutely terrible service