Jason Stein
@jsteinlab
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Associate to the Prof, UNC Neuroscience Center & Dept of Genetics
Chapel Hill, NC
Joined July 2017
RT @LTULab: New preprint from our lab led by an amazing team, @ckvuong and Alexis Weber, were we employ single-cell multi-omics in the deve….
biorxiv.org
Down syndrome is the most common genetic cause of intellectual disability, presenting with cognitive, learning, memory, and language deficits. The cellular and molecular mechanisms driving this...
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RT @NatureNeuro: Stimulating Wnt signaling reveals context-dependent genetic effects on gene regulation in primary human neural progenitors….
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RT @NanaMatoba: It’s been a long journey🚢, with about 1 & 1/2 year since posting on bioRxiv and of course even longer since the project sta….
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RT @AJHGNews: 📢New from @jsteinlab!.📰 #Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis.https:….
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RT @organoidscience: Dr. Jason Stein's lab (@jsteinlab) at @UNC determined the cross-site reproducibility of human cortical #organoid 🧫 (hC….
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RT @GeneticsSociety: The authors of @AJHGNews' latest article identify cell-type-specific genetic regulation of RNA editing and alternative….
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RT @hyejung_won: I am beyond excited to share our new paper on massively parallel reporter assays on schizophrenia-associated variants. Thi….
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RT @NilAygun8: We @jsteinlab are delighted to present our recent preprint investigating the impact of genetic variants on cell-type-specifi….
biorxiv.org
The function of some genetic variants associated with brain-relevant traits has been explained through colocalization with expression quantitative trait loci (eQTL) conducted in bulk post-mortem...
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RT @ZoltanMolnar64: Neocortical Neurogenesis in Development and Evolution edited by WIELAND B. HUTTNER is out Sup….
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RT @MagnesiumLass: Excited to share a new preprint on the cross-site reproducibility of human cortical organoids co-led with Elisa Waxman &….
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RT @JoVEJournal: Learn how Felix Kyere, Ian Curtin, Jason Stein and colleagues of @UNC perform whole-brain single-cell imaging and analysis….
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RT @NilAygun8: Our recent work together with @jsteinlab and @mikelove is published in @GenomeBiology, to understand cell-type specific caus….
genomebiology.biomedcentral.com
Background Genetic variation influences both chromatin accessibility, assessed in chromatin accessibility quantitative trait loci (caQTL) studies, and gene expression, assessed in expression QTL...
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RT @sj_marzi: Super excited to host @BrandonDLe from @jsteinlab next Tuesday at 3pm for the #neurogenomics seminars. Bran will present the….
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RT @MichelleItano: The lightsheet has landed! 🔬🤩🎉. After a lot of preparation and a full week of install, we were thrilled to see some imag….
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RT @gokberkalagoz: 2 major earthquakes hit Turkey and Syria on Monday affecting many cities where ~15 million people live. The death toll i….
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Check out our lab's recent work mapping response ca/eQTLs in the context of Wnt stimulation 🪄⚡️.
Excited to share our new preprint, where we investigated context-specific gene regulation and QTLs by stimulating 🪄⚡️ the Wnt pathway in human neural progenitor cells🧠 (co-led with two wonderful grad students @brandonDLe @jmvalone4 in @jsteinlab) 1/🧵
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RT @doctorveera: GWAS in a dish! .GWAS of neural progenitor cell proliferation on lithium treatment (n=80) identified a locus on chr 3, a k….
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RT @NatMentHealth: 🧬A GWAS study from @jsteinlab has found a common genetic variation that influences lithium-induced neural progenitor pro….
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RT @ElsevierNews: Cell culture-based GWAS approach identifies lithium-induced pharmacogenomic effects on human neural progenitor proliferat….
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RT @copenhaverlab: @UNC_Biology has a job search for a tenure-track Assistant Professor in neurobiology. UNC is a p….
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