
Todd Rice
@toddrice_ICU
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Critical care doc / physician scientist. Assoc Editor for Critical Care section of CHEST, Past-President ASPEN; ICU Ed and Todd-Caster
Nashville, TN
Joined March 2018
Excellent. I am definitely excited to see more data on bicarbonate and better understand its effects (and ? potential benefits) in our patients.
@toddrice_ICU The SodaBIC trial is going strong. More data in the bicarbonate front are on the horizon.
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Fluids are one of my favorite topics to talk about. We have learned a lot about composition of fluids that we give over the last decade (or longer). We discuss some of what we learn, plus new learnings from the FLUID study and some "provocative" results from BICAR-ICU from 2017.
Episode 71! We talk about FLUID published in @NEJM and BICAR-ICU from @TheLancet . FLUID: BICAR-ICU: ๐ง
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Always great to get one of (if not THE) world's experts on to join discussion. Have seen lots of talk about A2B, w/ different interpretations of clinical impact of the results. Listen in to hear what we think (in more detail than the editorial we wrote. .
jamanetwork.com
Critically ill patients receiving invasive mechanical ventilation often require continuous infusion of sedation to address pain and anxiety. The search for the single best sedative agent for critic...
Episode 70! We have @WesElyMD join us to talk about A2B by Walsh et al published in @JAMA_current May with the @ATSBlueEditor conference. Don't miss this one!. ๐ง A2B: JAMA: Editorial:
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If you haven't experienced this critical care bootcamp, you are definitely missing out. Fantastic educational experience. Hands on learning, didactic learning, networking. All in good ole' Nashvegas. A true destination education. Sign up now before spots fill up. #destinationedu.
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Two excellent studies that deal with liberating patients from mechanical ventilation. Great studies to discuss and think about the clinical implications of PAV+ weaning and diaphragmatic stimulation.
Episode 69! We talk about the articles from the #CCR25 conference with RESCUE-3 published in @ATSBlueEditor by Dres et al and PROMIZING by Bosma et al in @NEJM . RESCUE-3: PROMIZING: Listen:
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Awesome to have Dr. Seitz join us to talk about MODE and the upcoming MODEM trials. Ventilators have many different modes, and while we often spend time understanding how each mode works, understanding how different modes might affect our patients and outcomes is more difficult.
Episode 68! Today we talk about modes of mechanical ventilation with the first author Dr. Kevin Seitz. This was published in @accpchest April of 2025 . ๐ง: Pubmed:
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Training on POCUS, Airway management, and ventilator management - some of the foundations of critical care. Great 3 days at CHEST headquarters. Join us for some good learning and lots of fun.
Receive experience with bedside critical care ultrasound, airway management, mechanical ventilation, and common ICU procedures. Register now.
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Lots of new studies - some very interesting and intriguing (maybe even provocative) trials and results. This is a whirlwind review, but more detailed review in future episodes.
Episode 67! A simple one this time. Just a 50,000 ft overview of the presentations from the #CCR25 conference!.๐ง
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So many great learning opportunities - cutting edge science, didactic learning, roundtables, panel discussions, simulation (POCUS, procedures). It covers it all. And you get to enjoy Nashville in the evenings - WIN WIN!!!!.
Excited to attend the #CCBootcamp2025 this September in Nashville! Hands down one of the best med conferences for critical care NPs & PAs to engage with experts and expand their knowledge! #MedEd #MedTwitter ๐ฅ
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Although somewhat infrequent in our ICU admissions, acute chest syndrome is often complex with high morbidity. New treatments are badly needed. Appreciate Dr. Tillman joining us to discuss this RCT and the possibility of systemic anticoagulation benefitting these unfortunate pts.
Episode 66! We talk about Acute Chest Syndrome in Sickle Cell with one of our favorite hematologists, Benjamin Tillman! We base our discussion around the TASC trial published by Dessap et al in @ATSBlueEditor 2025. Pubmed: ๐ง
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Lots of good stuff to talk about - and what scores will the A2B "acronym" receive.
Excellent editorial on the A2B trial in @JAMA_current highlighting the need for dynamic sedation strategies for mechanically ventilated adults. Can't wait for a @IcuCast on this study!. @EdQian.
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More data suggesting there might not be a single best sedative for all critically ill (mech vent) pts. Ongoing study should look at phenotypes and use of different sedatives and whether the sedative agent should be dynamic across a patient's critical care course. @EdQian.
This Editorial discusses the A2B trial, which found that dexmedetomidine, clonidine, and propofol offer similar outcomes for sedating critically ill patients. #ATS2025.
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Really tried to dissect this study. Results are contrary to previous study findings. Just when I thought I had an idea about using steroids in CAP, this prompted a re-visit. Well worth a listen to hear the discussion and us floundering at the end as to how this affects practice.
Episode 64! We talk more about steroids in severe CAP with "Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial" published in ICM in 2025. pubmed:
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There are case series / cohorts for its use in post-op vasoplegia (which is obviously a known complication of cardiopulm bypass). The use of Angiotensin 2 in the post-op vasoplegia realm is definitely increasing. I don't know of any RCTs of it for this indication.
@IcuCast @JAMA_current Angiotensin 2 is a little off the podcast topic (so is snow) but I recently heard that there is theoretical benefit to using AngII in patients who are on cardiopulm bypass for prolonged periods. The theory being that without pulmonary blood flow you have reduced Ang1โ>2.
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Inhaled sevoflurane - used more during the pandemic with shortages of other sedatives - but now we have an RCT evaluating its effects. Excellent study and great discussion.
Episode 62! We talk about some of the articles from the ISICEM conference and talk in depth about SESAR published in @JAMA_current with the conference last month! .๐ง SESAR (pubmed): SESAR (JAMA):
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HFNC has truly changed the way that we practice. And we still have lots to learn about it (like when to optimally use it and how best to wean it). Great discussion around where things currently stand with regards to HFNC and what we still need to figure out.
Episode 61! We talk about HFNC including extubation to and how to wean it! Also, what do you think of when you think "auto-PEEP"?. ๐ง Auto-PEEP: Extubate to HFNC: Weaning HFNC:
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Yep. The ? is what can we do to overcome this anabolic resistance (and hint hint, the answ't provide higher levels of protein alone). Is it reduce inflammation? Stimulate the muscle? Anabolic steroids? something else? I predict this will be a big part of future of ICU nutrition.
@MatomeDietician @toddrice_ICU @LSChapple Yes! Preventing or limiting loss is what we can focus on, but is it even possible metabolically? The data says we can absorb protein during critical illness but we donโt always incorporate it into muscle, resulting in muscle turnover despite โadequateโ protein. #ASPEN25.
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