
ICUEdandToddCast
@IcuCast
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Two ICU guys walk into a recording studio and talk about the latest and greatest in ICU evidence
Joined December 2022
Episode 70! We have @WesElyMD join us to talk about A2B by Walsh et al published in @JAMA_current May with the @ATSBlueEditor conference. Don't miss this one!. 🎧 A2B: JAMA: Editorial:
jamanetwork.com
Critically ill patients receiving invasive mechanical ventilation often require continuous infusion of sedation to address pain and anxiety. The search for the single best sedative agent for critic...
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Episode 69! We talk about the articles from the #CCR25 conference with RESCUE-3 published in @ATSBlueEditor by Dres et al and PROMIZING by Bosma et al in @NEJM . RESCUE-3: PROMIZING: Listen:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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Episode 68! Today we talk about modes of mechanical ventilation with the first author Dr. Kevin Seitz. This was published in @accpchest April of 2025 . 🎧: Pubmed:
pubmed.ncbi.nlm.nih.gov
gov.
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Episode 67! A simple one this time. Just a 50,000 ft overview of the presentations from the #CCR25 conference!.🎧
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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Episode 66! We talk about Acute Chest Syndrome in Sickle Cell with one of our favorite hematologists, Benjamin Tillman! We base our discussion around the TASC trial published by Dessap et al in @ATSBlueEditor 2025. Pubmed: 🎧
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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Episode 64! We talk more about steroids in severe CAP with "Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial" published in ICM in 2025. pubmed:
pubmed.ncbi.nlm.nih.gov
Clinicaltrials.gov identifier: NCT02735707 (registration date: November 4th, 2016).
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Episode 63! We talk about thrombolysis in intermediate risk PE with PEERLESS published in @CircAHA and then PEITHO from @NEJM from 2014. PEERLESS: PEITHO: PE Meta-analysis: 🎧
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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Episode 62! We talk about some of the articles from the ISICEM conference and talk in depth about SESAR published in @JAMA_current with the conference last month! .🎧 SESAR (pubmed): SESAR (JAMA):
jamanetwork.com
This clinical trial compares the efficacy of inhaled sevoflurane vs intravenous propofol for sedation in patients with acute respiratory distress syndrome.
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Episode 61! We talk about HFNC including extubation to and how to wean it! Also, what do you think of when you think "auto-PEEP"?. 🎧 Auto-PEEP: Extubate to HFNC: Weaning HFNC:
pubmed.ncbi.nlm.nih.gov
High-flow nasal cannula (HFNC) is a first-line therapy for patients with acute respiratory failure. Despite increased HFNC utilization over recent years-accelerated in part by the COVID-19 pandemic...
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#59! We talk about TRAUMAOX2 (@JAMA_current), SAHARA (@NEJM), and answer some listener questions finishing our #ccrdownunder coverage. Great discussions!. TRAUMOX2: SAHARA: 🎧anywhere:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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#58! We talk about RENOVATE or "High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure" published .@JAMA_current and presented #ccrdownunder. We pair with FLORALI! . 🎧anywhere: . JAMA:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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Episode 57! We were excited to have @adamatw PhD in Bioinformatics to discuss SCREEN published by Arabi et al in JAMA 2024 and presented at #CCRDownUnder. A long episode but a lot of good discussion. SCREEN: Listen anywhere:
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#56! We talk about ADAPT-Sepsis or "Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis" published in @JAMA_current and presented at #ccrdownunder. 🎧anywhere: Pubmed: JAMA:
jamanetwork.com
This clinical trial assessed whether treatment protocols for monitoring C-reactive protein or procalcitonin safely reduced the amount of time critically ill adults with suspected sepsis received...
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2024 year-in-review and overview of #ccrdownunder! . TIGHT K: PROPHY VAP: REVISE: Withdrawal ECMO: DanGer SHOCK: Intubation guidelines:
pubmed.ncbi.nlm.nih.gov
Using a Delphi method, agreement among a panel of international experts was reached for 53 statements providing guidance to clinicians worldwide on safe tracheal intubation practices in patients with...
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Episode 54! In this episode we talk about antibiotic duration in bacteremia (BALANCE) and also antibiotic duration in Pseudomonas VAP (iDIAPASON). BALANCE: iDIAPASON: Listen anywhere:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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Episode 53! A shorter episode but a good one where we talk about IV vs IO access in cardiac arrest with two articles published in @NEJM. Also, great acronyms!. IVIO: PARAMEDIC-3: Listen anywhere:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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In this episode we talk about fevers in patients with acute neurologic injury (INTREPID) AND LTVV in acute neurologic injury (PROLABI). A good one!. INTREPID: PROLABI: Listen anywhere:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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A little overdue but this episode enjoy our LIVE SHOW from #CCBootcamp2024 on the NONSEDA trial looking at no sedation vs light sedation in mechanically ventilated patients. NONSEDA: Listen anywhere:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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In this episode we talk about the FAST trial looking at SBT technique and frequency published in @JAMA_current, presented @ESICM. We then talk a little bit about the IV fluid shortage and things we can do!. FAST: Listen anywhere:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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We are LIVE #CHEST2024! Thank you to all who came to listen! We talk about articles recently published in CHEST and preview some that'll be presented on Wed!. Minocycline for Delirium: Amio vs Lido: Listen:
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Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine...
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