Tarek
@tarekh247
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cryoEM associate | biochemistry faculty || FZEM | FUB | BIS
Berlin, Deutschland
Joined February 2019
And again, intriguing structures of the large ribosomal subunit @RainerNikolay.
Excited to share our new work on the proline-rich antimicrobial peptide Api137, which disrupts large ribosomal subunit assembly and induces RNA misfolding. Big thanks to the Spahn & Hoffmann groups for this amazing collaboration!
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I never realized acknowledgements for reviewing activities in papers. Is this new? Who actually reveals themselves? Asking for a friend. .
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This is huge. Congrats Hauke and team.
Happy to share the results of a great collaboration with Thomas Pfannschmidt (LU Hannover), led by the amazing @paulafprado and Frederik Ahrens. Together, we determined the structure of the multi-subunit plastid-encoded RNA polymerase from chloroplasts!.🧵
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Question to #teamtomo.What is currently your preferred workflow/software suite for STA starting from raw tilt series? Arguments welcome.
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😲 Amazed and surprised. Tungsten filament on a 120 kV Talos. Not the best specimen but, if you know you know.
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Herculean, cryoem structures of 17 antibiotics on the ribosome 👏 @WilsonLab2.
Our study on the "structural conservation of antibiotic interaction with ribosomes" is out in @nsmb. Mammoth effort led by Helge Paternoga and @caillancm reporting structures of 17 antibiotics in complex with the ribosome at 1.6-2.2Å resolution. PDF at.
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This is 🔥🔥🔥.
Coming soon. a pentacycline (as opposed to a tetracycline) on the ribosome at 1.9 Å resolution
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RT @PS_cryoEM: WE ARE HIRING 🇮🇹🦠⚛️🔬🌈! 2 posts for EM Specialist in Cryo-EM Unit of the National Facility of Structural Bio @humantechnopole….
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Quite something different than imaging proteins but seems like we're ready to elaborate application of STEM. #cryoem.What a ride, puh😅
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Can you see atoms? Seems like Köhler illumination is good for HRTEM as well.
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RT @MishaKudryashev: We are looking for a postdoc to join our group at the Max Delbruck Center @MDC_Berlin in Berlin. Its a broad call for….
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RT @MatthewKraushar: yo science twitter! . the Kraushar Lab @MPI_MolGen seeks a fearless bioinformatics postdoc on a collaborative project….
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RT @MishaKudryashev: We are looking for PhD students to join the MDC, including our group. We do great in situ structural biology with the….
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Still not where we've been @PhysikFUBerlin but on a good way to get our Krios running after the relocation to #suprafab @FU_Berlin.Thanks for your patience to our users, keep fingers 🤞
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Fantastic article on non-canonical translation termination in human mitos. Congrats @The_Ban_Lab .
science.org
Noncanonical stop codons AGA and AGG in human mitochondrial translation are recognized by mitochondrial release factor 1.
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Hot 🔥🔥🔥 @Intein tries to answer major questions on actin.
Where does phosphate go after ATP hydrolysis?. #cryoEM, in vitro reconstitution and #MD of #actin filaments explain inorganic-phosphate release: . Thanks to @WoutOosterheert @Anks_8D @flblanc @alexanderbelyy1 @HummerLab @PeterBieling @mpimoph @MPIbp
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