Gabriel (Gav) Sturm
@sturm_gav
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CompBio @CZbiohub SF mitochondrial dynamics, microscopy, and cellular lifespan.
Joined April 2020
2x Preprint drop!!! Mitochondrial pearling has arrived! .“The Biophysical Mechanism of Mitochondrial Pearling”. “Pearling Drives Mitochondrial DNA Nucleoid Distribution” 1/10.
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RT @MitoPsychoBio: Signals of energetic stress including GDF15 and others reach the brain to influence the aging process. Superb journalist….
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RT @MitoPsychoBio: New paper on mitochondrial distribution across the human body. If you have more mitochondria than the average person in….
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RT @MitoPsychoBio: Can we feel our mitochondria?. We feel pain (nociception), internal sensations (interoception), and even our immune syst….
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RT @GoogleAI: Today, in collaboration w/ colleagues at the Institute of Science and Technology Austria (ISTA), we report the first-ever met….
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RT @schoeneberglab: Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data!.@ecarkfeld @ZacharyWang….
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Nellie's image analysis capabilities are vast. I put a video of yeast mitochondria through Nellie and generated a 'live-cell MitoGraph' - a topological graph capturing mitochondrial network's fission and fusion events over time.
Do you LOVE organelles??.Well I am THRILLED to announce that Nellie has been published in @naturemethods! . Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy. 🧵1/N
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Nellie is out in Nature Methods! Analyzing live-cell bioimages is really hard. Nellie not only makes this analysis accessible but also brings out the full beauty of your data. Give it a try! (Nellie tracking mitochondria in Blender below).
Do you LOVE organelles??.Well I am THRILLED to announce that Nellie has been published in @naturemethods! . Nellie a fully automated pipeline for organelle segmentation, tracking, and hierarchical feature extraction in 2D, 3D, timelapse, multichannel live-cell microscopy. 🧵1/N
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RT @MitoPsychoBio: If you want to explore your favorite mitochondrial gene, function, or pathway in different human tissues and organs, hav….
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RT @MitoPsychoBio: All mitochondria in your body comes from the same "mother" population in the egg/oocyte, later differentiating into dist….
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RT @PathfinderEq: @sturm_gav Wow! We knew that mitochondrial DNA were evenly distributed along the inside membrane but didn't know how. T….
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RT @WallaceUcsf: The transient nature of pearling makes it hard to detect - in normal cells you might need to sit and watch one spot for a….
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RT @WallaceUcsf: All too often, when colleagues suddenly find themselves converging on the same question, it quickly becomes like a knife….
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RT @WallaceUcsf: We hope you will enjoy these preprints. I will just close with this holiday wish to everyone who celebrates mitochondria….
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RT @WallaceUcsf: Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.socia….
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RT @SulianaManley: I'm ultra excited about our preprints on mitochondrial pearling! In two concurrent collaborative studies with @WallaceUc….
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RT @jclandoni: Stoked to share TWO preprints on mitochondrial pearling! 🎉.We uncover how spontaneous #mitochondria pearling drives #mtDNA n….
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Thanks to my PhD advisor.@WallaceUcsf and all of our amazing collaborators, our biophysical model lays the groundwork for understanding pearling as an essential mitochondrial dynamic; integrating ionic flux, inter-organelle interactions, molecular motors, and bioenergetics. 10/10
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