RT @sruizmacias: I am really happy to share our latest work where we mapped the CDK activity landscape in live single cells during early mo….

RT @FASEBorg: Cell signaling researchers, there's only a couple weeks left for the early registration rate at this year's #DECSRC! @albeckl….

RT @CollinsLab1: Stefan's and Briana's paper on how differences in the duration of responses helps neutrophils decide which chemical trails….

Why are senescent cells irreversibly arrested in the cell cycle? Today in @CellReports we report in a study led by talented postdoc @Afifi_MM that the transcription factor MYC is constantly degraded, keeping the cells locked in a non-proliferative state.

RT @nussenza: Our new study-how inhibition of WRN helicase and ATR are selectively toxic in microsatellite unstable cancers. Work led by Da….

RT @werner_achim: When #ubiquitin meets🐣 @NIDCR: check out our inspiring collaboration with @kerosuoLab, revealing how early brain, craniof….

Thank you to all the co-authors including @AdrijanaCrncec, @Afifi_MM, Kristina Tang, and @ruhulmb. This project was a great team effort! .Thank you to @Alexis_Barr for writing a great News & Views.

Check out our new paper by the extremely talented postdoc @James__Cornwell out now in @Nature. For decades it was thought the cell cycle was irreversible, but now we show that is not the case.

RT @TobiasMeyerLab: Check out the cool paper from @NalinRatnayeke, a recent graduate from our lab on how cells ensure that #genome #replica….

Check out this great piece by Adrijana Crncec, a postdoc in lab, where she describes her academic journey. Just out in this week's issue of @ScienceMagazine. Luck helped me pursue an academic career. I worry about others who aren’t as fortunate

We will continue exploring how RTK signaling regulates beta-TrCP activity and use our new reporter to screen for new small molecule inhibitors and activators of beta-TrCP. Many thanks to our great team and collaborators! 3/3.

We found beta-TrCP is a relatively weak ubiquitin ligase that remains constantly active throughout the cell cycle. We conducted a high-throughput screen and identified RTK signaling as a key modulator of beta-TrCP coupling to the core SCF complex. 2/3.

Excited to share our new paper out in @NatureComms, led by our postdoc Debasish Paul. We developed a biosensor for the ubiquitin ligase beta-TrCP to study its activity in live, single cells. 1/3.

RT @TobiasMeyerLab: Don't miss this talk by Yumi, an outstanding postdoc of my lab!!!.

RT @InSiDE_Seminar: Join us on Thursday for another round of talks, this time by Marwa Afifi from @steve_cappell lab, and Carla Mulas @C_Mu….

RT @DeRobertus: Virtual Cell Cycle Club meeting, this Wednesday, February 23. PROGRAMME.3 short talks: @roylelab, @steve_cappell & O'Farre….

RT @DeRobertus: Digital Cell Cycle Club meeting, February 23. PROGRAMME.3 short talks: @clathrin, @steve_cappell & the O'Farrell labs .2 b….

My lab’s first paper is out in Science Advances! We uncover the origins of single-cell variability in cell fates after DNA damage. Huge thanks to the entire team who helped get this out despite a global pandemic.