Raphael Eguchi
@ryuichirapha
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Stanford University, Possu Huang Group Alumnus.
New York, New York
Joined April 2010
I'm happy to present Sculptor, a new epitope-specific generative protein design algorithm from @PossuHuangLab! Many thanks to our collaborators at the Bowman group @drGregBowman and IAVI for all their hard work! .
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RT @hackernewstop5: Shunpo: Minimalist bash tool to make directory navigation a little bit faster #HackerNews.https….
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RT @biorxiv_molbio: Changing protein-DNA interactions promote ORC binding site exchange during replication origin licensing. https://t.co/….
biorxiv.org
During origin licensing, the eukaryotic replicative helicase Mcm2-7 forms head-to-head double hexamers to prime origins for bidirectional replication. Recent single-molecule and structural studies...
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A very cool study from MIT Bell lab that studies the role of DNA bending in helicase loading! Congrats to Annie!.
biorxiv.org
During origin licensing, the eukaryotic replicative helicase Mcm2-7 forms head-to-head double hexamers to prime origins for bidirectional replication. Recent single-molecule and structural studies...
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How generative AI is building better antibodies
nature.com
Nature - Language models similar to those behind ChatGPT have been used to improve antibody therapies against COVID-19, Ebola and other viruses.
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RT @martinmbauer: I just learned that the first formula for calculating the n-th decimal digit of pi (without calculating all the preceding….
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Shout outs to our collaborators who collected the excellent molecular dynamics data for us, @Mickdub29 and @VithaniNeha!.
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RT @biorxivpreprint: Deep Generative Design of Epitope-Specific Binding Proteins by Latent Conformation Optimization .
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RT @sfchronicle: Berkeley's wildly popular Third Culture Bakery's success has been driven by its cult favorite mochi muffins. It trademarke….
sfchronicle.com
Berkeley’s wildly popular Third Culture Bakery has been quietly working to prevent...
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If you're looking to donate to Ukraine, this is a link shared by the official government twitter: .1. Click the fondy link on the page. 2. Change the language to english with the upper right menu. 3. Check the exchange rate and donate.
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RT @Ukraine: 2. Donate money to support the Ukrainian Army. You can transfer money to the following accounts:. 🇺🇦 .
bank.gov.ua
The National Bank of Ukraine has decided to open a special fundraising account to support the Armed Forces of Ukraine. The central bank’s decision comes after the Ukrainian gove...
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RT @jueseph: New preprint! We came up with 2 methods to design de novo scaffold proteins to hold arbitrary functional motifs: hallucination….
biorxiv.org
Current approaches to de novo design of proteins harboring a desired binding or catalytic motif require pre-specification of an overall fold or secondary structure composition, and hence considerable...
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RT @RolandDunbrack: I've never seen an antibody structure in the PDB where the authors were allowed to hide the sequence of all of the CDRs….
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Just @sokrypton doing great stuff as usual:.
github.com
Making Protein folding accessible to all! Contribute to sokrypton/ColabFold development by creating an account on GitHub.
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RT @arXiv_Daily: ForceNet: A Graph Neural Network for Large-Scale Quantum Calculations.by @weihua916 et al. includi….
deepai.org
03/02/21 - With massive amounts of atomic simulation data available, there is a huge opportunity to develop fast and accurate machine learnin...
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RT @Stanford_ChEMH: Faculty fellow Soichi Wakatsuki & co-workers have uncovered the mechanism behind glucose-6-phosphate dehydrogenase defi….
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RT @DeepMind: In 2016, AlphaGo was introduced. Two years later, its successor - AlphaZero - showed significant progress in Go, chess and sh….
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RT @DEShawResearch: Our article "Midtown splines: an optimal charge assignment for electrostatics calculations" was published online today….
pubs.aip.org
Transferring particle charges to and from a grid plays a central role in the particle–mesh algorithms widely used to evaluate the electrostatic energy in molecu
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