Rinie Bajracharya
@rinie_baj
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👩🏻🔬 Postdoc @IMBatUQ @inflammasomelab #neurodegeneration #tauopathy #neuroinflammation | My other interests include food, dogs and music :) Opinions = own
Australia
Joined January 2011
Absolutely stellar work by @CarolineLHolley and @inflammasomelab 👏 A really inspiring tale of how a curious observation evolved into an astounding story which provides previously unexplored insight into how inflammasome signalling shapes adaptive immune responses! 🎉
#NoTimeToDie! @inflammasomelab, Holley, Monteleone &co show @NatImmunol that cells that die by #pyroptosis, or #necroptosis, are crowned with F-actin filopodia that makes them visible by dendritic cells via CLEC9A to initiate adaptive immunity!
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EMCRA is hosting the final BBQ of the year! Come join us for a snag and a drink! No need to register.
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What are the hottest new drug targets for #inflammatory & #neurodegenerative diseases? #Inflammasomes of course - read this to find out why! Fun to get the band back together with @Rebecca_Coll for our new single 😀 @ASImmunology @UQ_News @NatRevImmunol
https://t.co/MWWKF2k9E4
NEW online: Inflammasome components as new therapeutic targets in inflammatory disease https://t.co/sjplRdpWio by @Rebecca_Coll @inflammasomelab discusses the use of small molecules or biologics to block pathological inflammasome signalling
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We are hiring! Two postdoc positions are available in my group, based at @UQMedicine (SBMS) and @QldBrainInst. Please RT. @UQ_News @DementiaAus @mndaustralia @postdoc @Postdocjobsaus @micro_au Ad1: https://t.co/tpWcoxbnnk Ad2: TBA
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*Reminder* Inclusivi-Tea Time 🫖 is next Monday (August 4th) @IMBatUQ rooftop at 9.30am. Our prepared topic will focus on non-binary identities, but feel free to discuss anything on your mind! Open to all. Bagel Boys bagels! Tea/coffee, BYO mug 📷See you there 📷😁
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ONE earmarked PhD scholarship is remaining for Aus/NZ citizens or Aus PR. If you're interested in advanced imaging, computational modelling, or brain disorders, please contact p.padmanabhan@uq.edu.au. @micro_au @DementiaAus @ANZIAMnews @uqnews @Scholarshipps @Askpstudyin_Aus
Our group has TWO earmarked PhD scholarships in Alzheimer's disease and brain cell communication. Lots of interdisciplinary approaches (advanced imaging/math modelling/biochemical techniques). DM/email (p.padmanabhan@uq.edu.au) me for more info. @UQMedicine @QldBrainInst @UQ_News
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Register for the IMB EMCR Retreat on August 15th! "The Ins and Outs of Leadership and Collaborations" Invited leaders, career insights and development, team bonding and networking. 📍 Venue: Viewpoint (UQ Building 33) ⏰ Time: 8:30 AM – 4:00 PM Register:
docs.google.com
Date: August 15th, 2024 Location: ViewPoint at St Lucia campus UQ Building 33, Union Road, St Lucia, QLD 4067 Theme: 'The ins and outs of leadership and collaborations.' Registration dates July 1st:...
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Our group has TWO earmarked PhD scholarships in Alzheimer's disease and brain cell communication. Lots of interdisciplinary approaches (advanced imaging/math modelling/biochemical techniques). DM/email (p.padmanabhan@uq.edu.au) me for more info. @UQMedicine @QldBrainInst @UQ_News
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The impact of LINE-1 retrotransposons on neurobiology is not fully understood. Our new research in @NatureNeuro sheds light on LINE-1 activity in PV interneurons, sparking fresh perspectives on its role in neurobiology. #neuronaldiversity #neurogenetics
https://t.co/YquGGHoFZW
nature.com
Nature Neuroscience - LINE-1 retrotransposons are a type of mobile DNA element normally repressed in the body. Here the authors show that LINE-1 sequences can jump in mouse parvalbumin interneurons...
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We report a new chemical #NLRP3 activator, forchlorfenuron. Like the imidazoquinolines, FCF induces the K+ efflux-independent pathway of NLRP3 activation by inducing #mitochondrial damage. Congrats to @CarolineLHolley @S_Emming & the @inflammasomelab team! https://t.co/NEOFliT6G3
The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis by @CarolineLHolley, @S_Emming, Kate Schroder @inflammasomelab, and colleagues at @UQ_News @IMBatUQ @mpiib_berlin
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Inclusivi-Tea Time 🫖 this Monday @IMBatUQ rooftop at 9.30am. Theme: Challenges and Strategies for International Students and Workers Feel free to share ideas or concerns you have about anything, discussion is open to all. Tea, coffee, and biscuits provided, BYO mug ☕️
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If you hear of any exciting opportunities or are open to chatting, please send me a DM or reply below! #OpenToWork #Brisbane #Australia
https://t.co/axebY2ONnb
au.linkedin.com
Experience: Translational Research Institute Australia · Education: The University of Queensland · Location: Brisbane · 352 connections on LinkedIn. View Rinie Bajracharya’s profile on LinkedIn, a...
Hi everyone! I’m on the lookout for a new role and would really appreciate your support. I'm particularly interested in chatting with #pharma, #biotech and #CROs about how my #biomedical #research skills may benefit your team. I am based in Brisbane, Australia.
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Hi everyone! I’m on the lookout for a new role and would really appreciate your support. I'm particularly interested in chatting with #pharma, #biotech and #CROs about how my #biomedical #research skills may benefit your team. I am based in Brisbane, Australia.
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Ever wondered how NLRP12 can drive autoinflammation? 👀 In our latest work, we show that NLRP12 is an endogenous inhibitor of NLRP3 inflammasome formation, but disease-causing NLRP12 mutants lose this capacity 🤯
New exciting work from the @inflammasomelab just out! Congratulations to @JaredCoombs_ , @DrAlinaZ , @CarolineLHolley and others! NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome | Science Signaling
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Studying mice and cells from patients with an autoinflammatory condition, a team finds the #inflammasomes NLRP3 and NLRP6—but not NLRP12—initiate formation of ASC specks and that NLRP12 may suppress NLRP3. @IMBatUQ @inflammasomelab @JaredCoombs_
https://t.co/Q7yju1Sa02
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We will be hosting an EOY BBQ at the rooftop @IMBatUQ this coming Friday! There will be beef, chicken and veggie sausages + soft drinks. Everyone is welcome! See you there 😃
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Excited to share our new preprint where we show that the permeability of therapeutic anti-tau antibodies is reduced in the #APOE4 #BBB model. Big thanks to all amazing co-authors from @QIMRBerghofer @QldBrainInst and @TheFlorey for their contributions!
biorxiv.org
Tau protein is a critical driver of neurodegeneration and an important drug target in Alzheimer’s disease (AD). Tau-specific immunotherapy has emerged as a promising treatment strategy for AD,...
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The @DehorterLab @QldBrainInst offers a fully funded #PhDposition to work on an exciting project on interneuron #development and #autism. MORE INFO here👉 https://t.co/WoqwY80zSN 👉 https://t.co/8tjmDPSuHY Deadline: September 30, 2023; Starting date: Jan 2024. Please RT!
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Delighted to have graduated from my PhD yesterday! Thanks so much to my amazing supervisors @inflammasomelab and @s_burgener, the entire inflammasome lab at @IMBatUQ, and the fam over from Ireland for all their support the entire time and for celebrating this PhD one final time!
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