Roger Castells-Graells
@rcastellsg
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Incoming Junior Group Leader at CNIO | Postdoc @UCLA @ RodriguezLab @Yeates_Lab // PhD @JohnInnesCentre / SciEd @whatifnet // #cryoEM #proteindesign #ai #dl
Joined February 2014
I'm thrilled to share our latest work on designing imaging scaffolds to determine the structure of small proteins using cryo-EM! https://t.co/FbXdjnABxG
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Very cool to see this structure from Miller et al. from the @Yeates_Lab 🔬
This October I’m drawing 1 molecule a day inspired by proteins in pdb @PDBeurope @buildmodels Day 4 Prompt MURKY Pdb 8T1M Domain with unidentified function 1842 from pathogenic bacteria There are many proteins with known structures but their function remains murky Next DEER
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This October I’m drawing 1 molecule a day inspired by proteins in pdb @PDBeurope @buildmodels Day 4 Prompt MURKY Pdb 8T1M Domain with unidentified function 1842 from pathogenic bacteria There are many proteins with known structures but their function remains murky Next DEER
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We’re looking for an enthusiastic postdoc to join our team. 😊 The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪 Position funded for 3 years. Please share 🙏 Job description and details (deadline: October 11th):
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🔬 En el marco del #DíaMundialDeLaInvestigaciónContraElCáncer compartimos la historia de Pablo, investigador del @CNIOStopCancer. 🙌Su misión: usar la #InteligenciaArtificial para crear nuevas proteínas que ayudan a tratar tumores.
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Verano de bachillerato en el laboratorio: Aitana Soler y Jan Magem viven la realidad de la investigación científica en #CNIOStopCancer con el programa ‘Jóvenes y ciencia’ de la @FCLP_Fundació. Han trabajado un mes en el grupo de @rcastellsg, que también participó en este programa
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¡No te pierdas las 📰#NoticiasBreves_iSanidad de hoy! @SBEsp @rcastellsg @CNIOStopCancer @ppopular @EsterMunoz85 @NunezFeijoo @anefp_org @mufaceoficial @Edelman_Spain @sanitas
https://t.co/s24t3VfeFG
isanidad.com
Redacción La Sociedad de Biofísica de España premia al investigador del CNIO Roger Castells-Graells La Sociedad de Biofísica de España (SBE) ha entregado el premio Hawk Biosystems al investigador del...
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El @CNIOStopCancer crea ‘nanopartículas de proteínas’ para acelerar el desarrollo de fármacos contra el cáncer https://t.co/TibpxiSYT9
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Honored and grateful to receive the @HawkBiosystems Award from @SBEs 🙏 Thank you very much for this recognition!
Roger Castells-Graells receives the @HawkBiosystems Award from the @SBEsp, which acknowledges researchers under 33 years of age in the field of biophysics. @rcastellsg leads the Biomolecular Design and Structural Nanomedicine Group at #CNIOstopcancer. https://t.co/oxl2dYIKkN
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Roger Castells-Graells, Premio @HawkBiosystems de la @SBEsp a la trayectoria de investigadores de menos de 33 años en el campo de la biofísica. @rcastellsg dirige el Grupo de Diseño Biomolecular y Nanomedicina Estructural de #CNIOstopcancer. https://t.co/xHEZBhnnJ5
cnio.es
El investigador Roger Castells-Graells, del Centro Nacional de Investigaciones Oncológicas (CNIO), ha recibido el premio “Hawk Biosystems”, que otorga la Sociedad de Biofísica de España (SBE) en el...
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🧬 Roger Castells es doctor en Bioquímica y uno de los 374 investigadores del programa Construyendo la Generación IA, impulsado por https://t.co/SZ456kZSeT. Actualmente lidera un grupo en @CNIOStopCancer que diseña terapias contra el cáncer usando #InteligenciaArtificial👇
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El #CNIOStopCancer crea ‘nanopartículas de proteínas’ para acelerar el desarrollo de fármacos contra el cáncer y detectar antes la enfermedad. Es el objetivo del nuevo Grupo de Diseño Biomolecular y Nanomedicina Estructural, dirigido por @rcastellsg https://t.co/GPCfAmf69l
cnio.es
Las proteínas son moléculas complejas que realizan funciones cruciales en el organismo. Conocerlas es esencial para comprender e intentar curar enfermedades: si se conoce la estructura tridimensional...
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Interesting in learning to process cryo-ET data in the latest version of Warp? I'll be running a workshop on April 22nd in central London, UK details+registration: https://t.co/s3k1mWyB4A Hope to see you there!
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We're thrilled to present ESM3 in @ScienceMagazine. ESM3 is a generative language model that reasons over the three fundamental properties of proteins: sequence, structure, and function. Today we're making ESM3 available free to researchers worldwide via the public beta of an API
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Link to publication: “Design of a symmetry-broken tetrahedral protein cage by a method of internal steric occlusion”: https://t.co/QHf1BibfQK Link to Protein Science's special issue on Protein Design:
onlinelibrary.wiley.com
Click on the title to browse this issue
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Inspired by Hilma af Klint's The Swan, No. 8, the cover illustrates how we break the symmetry of a previously symmetric protein cage, pushing the boundaries of protein-based assemblies and expanding the design space. Kudos to Nika Gladkov for the stunning design!
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Thrilled to share that our latest research on breaking the symmetry of designed protein cages has been featured on the cover of Protein Science's special issue on Protein Design! #proteincages #proteindesign #symmetrybreaking
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In the end, I just want to say a big THANK YOU to all my mentors and friends for shaping my journey in Norwich into such an incredible and enriching experience! (8/8)
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New Year, new beginnings... but first, I would like to THANK everyone I've crossed paths with during the last 8.5 years at @TheSainsburyLab @JohnInnesCentre 🧵 (1/8)
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REGISTRATION OPEN - CNIO meeting, Machines acting on DNA and RNA, 2025 May 28-30th in Madrid, organized by @NogalesLab , @rfleiro , @LlorcaLab Bringing leaders in structural biology in Chromatin structure, DNA repair, RNA processing, Replication, Transcription and Translation.
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Few more new PDBs released from us before the end of the year :)
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