Christopher Rajkumar
@rajkumar_chris
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Interventional Cardiology Fellow | MRC Clinical Research Training Fellow | Imperial College London
Joined December 2017
Had a great time at #ECAS2025 as the only interventionalist at an EP conference! Fantastic to see a full session on the placebo effect in cardiology. Thanks to the organizers for the invite @ECAS_Heart . Now to #EuroPCR @PCRonline
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RT @monaltiren: #EuroPCR 2025. PCR’s Got TALENT. 1️⃣ 3 min / 3 slides. 2️⃣ 5 min / 5 slides. 3️⃣ 8 min / 8 slides. 🫵 Support & VOTE !. Pre….
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RT @fiyyazAJ: 𝐃𝐒𝐄 𝐝𝐞𝐥𝐢𝐯𝐞𝐫𝐬 𝐢𝐧 𝐎𝐑𝐁𝐈𝐓𝐀-𝟐: Stress echo ischemia identifies who 𝘳𝘦𝘢𝘭𝘭𝘺 benefits from PCI. 📖 𝐉𝐮𝐬𝐭 𝐩𝐮𝐛𝐥𝐢𝐬𝐡𝐞𝐝 𝐢𝐧 #𝐉𝐀𝐂𝐂: https://t.….
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RT @rajivxgulati: Tons of high-value case-based presentations covering CAD arrhythmia HF shock and more. Come join! @benhibbertMDPhD @stanh….
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RT @DrDerekConnolly: Great morning at @RCPhysicians talking about preventive Cardiology on the @BritishCardioSo @MayoClinicCV Cardiology Re….
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Are the Appropriate Use Criteria (AUC) for revascularization still aligned with the latest evidence? . New insights from ISCHEMIA challenge key assumptions. My two cents in @CircOutcomes It’s time to rethink outdated priorities.
Evaluating the Appropriate Use Criteria for Coronary Revascularization in Stable Ischemic Heart Disease Using Randomized Data From the ISCHEMIA Trial #AHAJournals @GreggWStone @SripalBangalore
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RT @BritishCardioSo: Join us at our Cardiology Review Course with @MayoClinic from Monday 10 - Friday 14 March at @RCPhysicians >> https:/….
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I think so, what else explains an initial high event rate which then subsides (aortic stenosis doesn’t get better!)?. Great if you can manage the first 6 months of subtraction anxiety - event rate then tracks the TAVR arm. Psychology so important in clinical trials. @drjohnm.
@rajkumar_chris @drjohnm @ProfDFrancis @rallamee @bnallamo Thanks @rajkumar_chris for chiming in. For us new to the concept of subtraction anxiety: . Is the suspiciously pointy corner (immediate change in slope) of the panel A&D yellow curve just before 0.5yr a finding that is pathognomonic for subtraction anxiety?.
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Should PCI be an option for first line management of stable angina symptoms? . Point and counterpoint in @CircOutcomes with final word from @bnallamo and @TCTMD . @rallamee
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Check out our journal club with @OPCILive on ORBITA-STAR and the symptom stratified analysis of ORBITA-2 @rallamee @FloSimader @ImperialNHLI.
Watch This Week's Episode of OPCI Journal Club: “ORBITA-STAR Trial and the ORBITA II Symptoms Analysis” presented by @rallamee @rajkumar_chris and @FloSimader. Joined by panelists @djc795 @JWMoses @ESHLOF and Dr. Lawrence Garcia. #cardiotwitter
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RT @JEscaned: Excellent discussion of ORBITA-STAR by @michaeltct Simple findings like those made in this study pave the way to solve a majo….
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Thanks to @JACCJournals and @PCRonline for showcasing, and the patients who made ORBITA-STAR possible! Hopefully a step toward more targeted treatment.
#ORBITA-STAR: Symptom-to-stenosis mapping may allow #PCI to be targeted to those most likely to benefit. Learn more in #JACC: #CardioTwitter @rajkumar_chris @rallamee @MikeFoley89
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RT @angioplastyorg: ORBITA-STAR at #EuroPCR is a fascinating & successful study of type of chest pain as a predictor of PCI success. Very d….
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Always a privilege to work with incredible statisticians (and cardiologists) @f2harrell and @mshunshin. This time for ORBITA-STAR. @ImperialNHLI @ImperialNHS @JACCJournals.
@rajkumar_chris @rallamee @MikeFoley89 @FloSimader @fiyyazAJ @DrKeeble @DrPeterOKane @JACCJournals @PCRonline @SukhNijjer @ProfDFrancis @mshunshin As a statistical modeler who does clinical research, a figure like this is a reason for being - it’s even got Bayesian uncertainty intervals.
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In ORBITA-STAR, angina verification with an ischaemic stimulus powerfully predicted response to PCI. #EuroPCR2024 . Perhaps we have been too focused on treatment when the problem always lay in the diagnosis! Published today in #JACC @rallamee
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Q: Does blinding matter in RCTs of surgical procedures? A: Depends on the endpoint @JAMASurgery . We compared placebo-controlled and open-label surgical trials to identify when the placebo effect is most powerful @rallamee @KatieEljadi @ImperialNHLI .
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Amazing to see a brilliant friend and colleague @MikeFoley89 present the #ORBITA-COSMIC trial of the coronary sinus reducer with simultaneous publication in @TheLancet @rallamee @ImperialNHLI @ImperialNHS #ACC2024 .
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RT @rallamee: Here we go again! Want to see if the coronary sinus reducer works in refractory angina? Watch @MikeFoley89 present the result….
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RT @GD_Thornton: Exciting insights from our @BSCMR Valve Consortium, presented at #CMR2024 and featured in #EHJ: In severe AS, myocardial s….
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