
Kunal Rai
@raikunal
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Associate Professor at MDACC; Student of Life; Passion = Chromatin and Cancer; Aspire to make a positive difference.
Houston, TX
Joined July 2010
RT @FLGenomics: Join us at #FoGBoston for insights from @raikunal (Associate Professor & Scientific Director, @MDAndersonNews Epigenomics T….
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Our new study shows NRF2-driven enhancer reprogramming contributes to chemotherapy resistance in head and neck cancers, providing rationale for targeting NRF2 to overcome cisplatin resistance. Led by @earslan_tamu and Dr. Abdullah Osman. @MDAndersonNews .
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Recently got my trophy for Potu N Rao Award for Excellence in Basic Science 2022. Many thanks to Division of Cancer medicine @MDAndersonNews for the recognition. I owe to this to the tireless efforts of the present and past trainees in my lab.
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Our preprint on epigenome reprogramming in R and NR melanoma patients treated with ICB suggests an enhancer biomarker and BETi+aPD1 combo. Great collaboration with @manoliskellis @gmboland @MMattohti @tangming2005 @JenWargoMD @dliu_ccb @MDAndersonNews .
biorxiv.org
Immune checkpoint blockade (ICB) therapy has improved long-term survival for patients with advanced melanoma. However, there is critical need to identify potential biomarkers of response and action...
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RT @Aiims1742: Preprint @raikunal @MDAndersonNews with @gmboland @MGHCancerCenter .@manoliskellis @MIT: .Enhancer Reprogramming in Melanoma….
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RT @JCI_insight: Comparable tumor immune microenvironment in human glioblastoma & murine model: @Zamler_Brain @Jian….
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Our collaborative work with Joe Ludwig on DSRCT,showing AR as a therapeutic target that functions through epigenome reprogramming, appeared today in @NatureComms . @MMattohti @MDAndersonNews .
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Thankful to CPRIT for their support of our research. @MDAndersonNews.
BREAKING NEWS: CPRIT announces 74 new grants for over $112 million to expand innovations in cancer research and prevention in Texas. Check out the release for the entire list of awards. #CPRIT #TexansConquerCancer .
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RT @CPRITTexas: BREAKING NEWS: CPRIT announces 74 new grants for over $112 million to expand innovations in cancer research and prevention….
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RT @MDAndersonNews: New research identifies mechanisms behind how fasting can reduce the negative effects of high-dose chemotherapy and rad….
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Collaborative work with @HusseinAbbas01 @Daver_Leukemia @IamLinghua online now. @KatTomcat1 @praveenbarrodia from my lab contributed significantly to this work. Congrats to all!.
nature.com
Nature Communications - The response rate of relapsed/refractory acute myeloid leukemia patients to PD-1 checkpoint blockade is low and unpredictable. Authors here show by single cell RNA...
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RT @IamLinghua: Congrats to @HusseinAbbas01, my postdoc Dapeng and the team | Single cell T cell landscape and T cell receptor repertoire p….
nature.com
Nature Communications - The response rate of relapsed/refractory acute myeloid leukemia patients to PD-1 checkpoint blockade is low and unpredictable. Authors here show by single cell RNA...
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Our study on chromatin states in metastatic melanoma came out today. We demonstrate genotype-specific chromatin state patterns and suggest use of PRC2 inhibitors in NRAS-mutant melanoma. @tangming2005 Chris Terranova Mahinur Maitituoheti.@MDAndersonNews.
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Also, sharing a review we wrote about application of machine learning tools in epigenomics with a focus on cancer research. @earslan_tamu Jonathan Schulz.
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Our new collaborative paper with Dr. Keila Torres, sheds light into the biology of and suggests therapeutic approaches for PRC2-deleted MPNST - a soft-tissue sarcoma. Led by Veena Kochat & @aayushraman . @MDAndersonNews .
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RT @kevansf: It’s time to change this slide! @FDA approval today of #sotorasib. Congrats @JonathanOstrem & Ulf Peters on launching the succ….
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