StoP-AD Center
@prevent_ad
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Center for Studies on the Prevention of Alzheimer's disease, McGill University, Montréal, Qc, Canada. AD dementia, biomarkers, prevention.
Montréal, Québec
Joined June 2018
1/5 We are about to release the PREVENT-AD Stage 2 open dataset that will include PET, MEG, … and 5 yrs of additional cognitive FU. 🥳 @alexa_pichetb @prevent_ad
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Study found that Aβ and tau PET positivity in cognitively unimpaired individuals was associated with near-term progression to mild cognitive impairment and, among those who do not show such categorical change, longitudinal cognitive decline.
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1/3 New lab paper suggesting, in 4 independent cohorts of cognitively unimpaired individuals, that the presence of both amyloid and tau-PET positivity is associated with near-term #AlzheimersDisease clinical progression. Strong support for the NIA-AA preclinical research criteria
Study found that Aβ and tau PET positivity in cognitively unimpaired individuals was associated with near-term progression to mild cognitive impairment and, among those who do not show such categorical change, longitudinal cognitive decline.
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Our most important clinical paper so far. In the @prevent_ad, 60% of our cognitively unimpaired participants with amyoid and tau PET binding developed MCI in ~2 years, a number that increased to 80% in those with hippocampal atrophy. The findings are replicated in 3 cohorts.
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New article from @sylv_villeneuve 's team, @prevent_ad in @NatureComms Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease https://t.co/cOnIY5gjtV
#alzheimer #brain #amyloidosis #aging #MachineLearning
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Looking for motivated Data Analyst for multimodal analyses in neurodegeneration (e.g. Alzheimer's). Mathematical, statistical, machine-learning skills and interest in neurobiology are requirements. For details, please check
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Six of our researchers obtain a CIHR Project Grants Congratulations @markpaulbrandon @MCGeoffroy R. Mizrahi, J. Poirier, @pedrorosaneto @sylv_villeneuve
https://t.co/VF147j8nHH
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PhD opportunity‼️ I am looking for a #PhD student to investigate the influence of #lifestyle on #cognition & #neuroimaging markers of #ageing and #Alzheimer Access to the offer and application details below 👇
New PhD job opportunity in #psychology #neurosciences based in Caen. Find out more ⬇ @Inserm
@ChetelatLab 🇬🇧 English: https://t.co/GDmxNQobxr 🇫🇷 French: https://t.co/U3fThnBv9e
#PhD #research #jobopportunity #brainhealth #ageingpopulation #meditation
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Find out what the PREVENT-AD is, what data is made openly available and where to get it @NeuroLibre! Thank you to all who contributed to acquire and make this data available. We look forward to the community using the data! #openscience
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Open Science Datasets from PREVENT-AD, a Longitudinal Cohort of Pre-symptomatic Alzheimer’s Disease
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McGill to me: “I am pleased to inform you that the Board of Governors of McGill University has approved the grant of tenure and the promotion to the rank of Associate Professor to you...” I GOT MY TENURE !!
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Paper in @elife: How whole-brain gene transcripts drive interactions among tau, amyloid, CBF, structural changes and pathology spreading in Alzheimer’s and Aging? Results from multi-scale universal formulation, by brilliant PhD-candidate @technoryta, https://t.co/9Msuwktzh6
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Another beautiful paper by @alexa_pichetb in collaboration with @maxdescoteaux using novel pipelines from @scil_udes. https://t.co/7SAW8APiCl
@eLife @mcgillu @DouglasResearch @prevent_ad #Alzheimers #STEM #amyloid #tau
elifesciences.org
White matter microstructure alterations in key bundles affected in Alzheimer's disease are related to amyloid and tau pathology in the preclinical phase of sporadic and autosomal-dominant Alzheimer's...
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Congrats to @SivaniyaSubram for acceptance of her paper “Sex differences in brain aging among adults with family history of Alzheimer’s Disease and APOE4 genetic risk” w @j_snytte in collaboration w @arossotto @EinsteinLabUofT in NIMG:Clinical! Stay tuned for #openaccess link!
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New paper from the lab suggesting that vascular risk factors are associated with a decline in resting-state functional connectivity over time in the @prevent_ad cohort. Vascular risk factors should really be more targeted for healthy aging and AD prevention.
Proud to present our latest findings on the association between vascular risk factors and longitudinal resting-state functional connectivity in @prevent_ad! All my thanks goes to such a great team @sylv_villeneuve, @alexa_pichetb, @_JakeVogel_, @pf_meyer
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Proud to present our latest findings on the association between vascular risk factors and longitudinal resting-state functional connectivity in @prevent_ad! All my thanks goes to such a great team @sylv_villeneuve, @alexa_pichetb, @_JakeVogel_, @pf_meyer
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You can access more of the PREVENT-AD data openly! A lot of work has gone into this, particularly from @sylv_villeneuve’s team. It was a lot work but we are delighted to share this with you! #openscience
1/14 Once upon a time (>2 years ago), we started the journey of making the PREVENT-AD data open. We had to reconsent the participants, develop the platform to host and share the data (thanks to Alan Evans and @NeuroLibre teams), clean the data and create the data dictionary.
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Our very own @alexa_pichetb has brilliantly defended her PhD thesis! Alexa has been instrumental in the centre’s work in the last 5 years. We look forward to her post-doc with @OskarHansson9 and the @biofinder_study. Congratulations Dr. Pichet Binette!
@alexa_pichetb defended her PhD thesis today, she did an AMAZING job. I am extremely fortunate we worked together for the past ~5 years. She is a role model scientist and an extraordinary person. Looking forward to follow her new projects with @OskarHansson9 #WomenInSTEM
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