
Piero Ricchiuto
@pieroricchiuto
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Principal data scientist in Bioinformatics, quantitative MS proteomics, algorithms, software dev, dad, snowboarding and motorcycles. Imagination is our limit.
Joined January 2020
We aimed to make it accessible & robust. Enjoy.
Our protocol for single-cell proteomics by mass-spectrometry was just published in @NatureProtocols: https://t.co/lXAEXfDA2A | OA link: https://t.co/UojepcLUqt
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This graphic could hardly be clearer
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The Delta wave impact in 14 countries by % vaccination and case spread —Israel, no longer in the top 10 for vaccination, is an outlier, > 100/100,000 —the US and UK ~50/100,000 —the rest are in descent or below 20/100,000 Delta can be beat. 11 of 14 countries are doing it.
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This table summarizes how extensive mRNA testing has been for 7 other infectious diseases, cancers, and genetic disorders. And while published this month, still not up-to-date. This is not "experimental gene therapy" —that is fabricated disinformation by anti-vaxxers
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On the mix and match vaccine front, a 2nd new study shows a significantly better immune response for AZ then mRNA than either 2 AZ shots or 2 mRNA shots @TheLancetInfDis
https://t.co/PgT6KoIAS9
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To the lady that had a melt down at the pharmacy today because she was offered Moderna instead of Pfizer. You're picking and choosing between different types of lobster for lunch while the world starves. Enjoy your night.
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Confronting >90% Delta variant. Israel, with the highest level of adult mRNA fully vaccinated population, seeing most cases today in > 3 months. One death after 10 days of none. Still well contained, but shows the challenge this strain presents @OurWorldInData + today's update
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In the UK, where 1st dose vaccination of adults is 82% and fully vaccinated 50% (US is 65% and 56%, respectively) Delta marches on. Today's UK data:
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Has #SARSCoV2 reached peak fitness? Will its further evolution provide resistance to our vaccines? @RobertoBurioni and I explore this issue in a new @NatureMedicine essay https://t.co/oQtarwt09C
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We have started to review applications- send yours in with your portfolio ASAP if you are interested in joining us.
Designers, data and crypo-artists: Join the @BarabasiLab! We are hiring https://t.co/FcdFIJ18Es Understand the world through networks, science, data, and images. See our work on https://t.co/L3W0NrMXIS and at @zkmkarlsruhe and @ludwigmuseum
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The work on #Red2Onco by IMBA Group Leader Bon-Kyoung Koo @koo_lab and the Simons lab at @GurdonInstitute is now published in Nature @NaturePortfolio Direct link to the paper in Nature ➡️ https://t.co/EhRM2kT7OK
#precancerous #earlydetection #cancer 2/2
nature.com
Nature - By inducing changes in surrounding tissue, mutant intestinal stem cells create an unfavourable niche environment that gives them a competitive advantage over non-mutant neighbours.
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PTMs in Human Disease B/D-HPP WEBINAR showcasing approaches to investigate post-translational modifications (PTMs). April 26. @hupo_org @CSIC @ProteoRed
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The rare disease world is fascinating and at Alexion we are looking for two #bioinformaticians passionate about clinical -omics data and willingness to learn about RWD and diagnostic opportunities - happy to tell you more about the role and our mission.
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A systems-based method to repurpose marketed therapeutics for antiviral use: a SARS-CoV-2 case study
life-science-alliance.org
This study describes two complementary methods that use network-based and sequence similarity tools to identify drug repurposing opportunities predicted to modulate viral proteins. This approach...
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Very true.
Clinical trials are not the real world of people; they all have inclusion/exclusion criteria. Like no history of anaphylaxis (protocol👇). The same day @Pfizer vaccine rolled out, 2 cases of severe allergic reactions in healthcare workers. There will be more safety issues ahead.
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Diagnosis and Screening of Patients with Hereditary Transthyretin Amyloidosis (hATTR): Current Strategies and Guidelines.
pubmed.ncbi.nlm.nih.gov
The outlook for transthyretin amyloidosis (ATTR) is changing with the availability of new and emerging treatments. ATTR now appears to be more common than previously thought and is no longer viewed...
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Northeastern University has dismissed 11 first-year students after they were caught violating social distancing rules, the school announced Friday. Their $36,500 tuition for the semester will not be refunded.
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A very troubling message I just got from a friend of our family
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