orthweinlab
@orthweinlab1
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DNA repair lab located at the Winship Cancer Center as part of the Department of Radiation Oncology, Emory @EmoryUniversity @WinshipatEmory @Emorymedicine
Atlanta, GA
Joined November 2015
New work reveals the impact of anxiety & depression on PhD students. "Anxiety and depression can have a substantially detrimental impact on graduate students’ experiences [..] and likely also contribute to increased time to degree and student attrition." https://t.co/iNitLTuagj
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We are organizing a FREE small symposium on DNA replication and replication stress on December 2nd and 3rd in Montpellier, France. Slots are still available for posters and talks. More info here:
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Check out the 2025 lineup of Social DNAing! Exciting new talks. We will also host 4 webinars in collaboration with NAR/NAR Cancer @NAR_Cancer_EIC to celebrate their 5-year birthday! Full programs will be on the website in 10 days. Stay tune.
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Pleased to collaborate with @zha_lab to present NAR Cancer 5th anniversary symposium - Manipulating DNA repair and the DNA damage response to improve cancer therapy. Eight stellar speakers - details soon on our web site.
Check out the 2025 lineup of Social DNAing! Exciting new talks. We will also host 4 webinars in collaboration with NAR/NAR Cancer @NAR_Cancer_EIC to celebrate their 5-year birthday! Full programs will be on the website in 10 days. Stay tune.
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Thank you! @LivUniISMIB @LivUniHLS
Meet #LivWiSErolemodel Professor Sonia Rocha, Executive Dean of the Institute of Systems, Molecular and Integrative Biology. Find out more about Sonia > https://t.co/NxGzPC1EYy
#LivWiSEis10 @LivUniHLS
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Ten research teams co-led by investigators from Winship and the American Cancer Society (@AmericanCancer) have been awarded a total of $1 million in pilot grant funding to accelerate research in cancer. ➡️Learn more: https://t.co/0WSbqZMRDQ
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Very excited to present the latest preprint from our lab! "FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments" https://t.co/HtuT9ZiNfW .
biorxiv.org
Homologous recombination (HR) deficiency upon BRCA2 loss arises from defects in the formation of RAD51 nucleoprotein filaments. Here, we demonstrate that loss of the anti-recombinase FIGNL1 retains...
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The department of Chromosome Biology of the Max planck @mpipz_cologne is looking for a new group leader. Join us, with @Polina_Novik @marques_et_al @LabSchneeberger We are very open minded concerning the project, it just needs to be exciting. https://t.co/nPW39pAJHM
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The isolation of the BRCA1 gene 30 years ago ushered in the era of genetic testing for breast and other cancers, launched a long-lasting patent battle and eventually led to a tailored cancer therapy
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📣 Excited to share our latest review on 53BP1’s function in replication stress, its role in fork protection, and the significance of 53BP1 nuclear bodies in this context! https://t.co/TnaMZWUEP4
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🥳Today @pnas, we reported CRISPR-Translate, a genome-wide CRISPR-Cas9 knockout screen-based method designed to identify factors regulating translation. We discovered IRF2 as a novel regulator of OAS3/RNase L-mediated RNA decay during viral infections.
pnas.org
OAS-RNase L is a double-stranded RNA-induced antiviral pathway triggered in response to diverse viral infections. Upon activation, OAS-RNase L supp...
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Do you want to know more about the RNA-mediated modulation of double-strand break repair? Follow our next GiiN seminar by Francesca Storici @StoriciL (@GeorgiaTech) next Tuesday (Nov, 5th)! At 5 pm (Rome) - 11 am (NYC) on Zoom: https://t.co/Aaml0MnmGS
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Join us for the annual Winship Scientific Symposium at the Emory Conference Center Hotel on Monday, Nov. 11, 2024. Registration is complimentary and includes meals and refreshments. ➡️Register today: https://t.co/ofoUwTEeM9
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On my way to the @WhiteSuttonFdn Conférence to meet families affected by this disease and scientists to work tirelessly to understand it. So much looking forward to meet them all and talk about the work of the lab on POGZ!
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We’ve arrived! #WhiteSuttonSyndrome Foundation is onsite at the #RosenCentreHotel to setup for #WhiteSuttonTogether 2024! Just a few meetings today before beginning to set up tomorrow. We can’t wait to see your smiling faces in 2 DAYS!! #POGZ
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Happy to see our collaborative paper with Cyrus Vaziri’s lab demonstrating that RNF168 is recruited to damaged replication forks via a degenerative PIP box and its MIU1 ubiquitin binding domain is finally out in @NAR_Open : https://t.co/sCQwkjKC5m
academic.oup.com
Abstract. RNF168 orchestrates a ubiquitin-dependent DNA damage response to regulate the recruitment of repair factors, such as 53BP1 to DNA double-strand b
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Join us in beautiful Ventura for the 2025 GRC meeting Mammalian DNA Repair: Fundamental Mechanisms to Human Biology https://t.co/92pKBd6XPV… Great program, including keynotes from David Pellman and Maria Jasin. Many talks and poster slots still available. Apply soon!
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Winship researcher and physician Reshma Jagsi, MD, DPhil, (@reshmajagsi) has been elected to the National Academy of Medicine (@theNAMedicine), one of the highest honors in health and medicine. ➡️Read more: https://t.co/hcpK63njeI
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