Ossama Kashlan
@okashlan
Followers
41
Following
30
Media
1
Statuses
19
Scientist at the University of Pittsburgh. Views are my own.
Pittsburgh, Pennsylvania
Joined February 2009
Our new study! Bile acids are natural ligands for the epithelial sodium channel. Big thanks to the Pochynyuk and Lei groups for their help! https://t.co/G85a3WrOzW
1
6
28
Kidney-Specific KO of the Circadian Clock Protein PER1 Alters Renal Sodium Handling, Aldosterone Levels, and Kidney/Adrenal Gene Expression - new in @AJPRenal
https://t.co/6kJNrRFvHB
#homeostasis #articlesinpress
0
7
19
‘I Want To Be In The Olympics Someday,’ Says Delusional Kindergartner Already 4 Years Behind In Elite Training https://t.co/e2mZuX8B3A
18
440
6K
Control over the activation of the #ENaC sodium channel through the addition of cleavage sites happened during the vertebrate land invasion.
en.wikipedia.org
0
0
0
Adaptations to breathe air and conserve salt and water gave aquatic vertebrates access to new resources on land. These required molecular changes.
1
0
0
Excited to share our latest work in @eLife with @NathanClark111 on the evolution of a sodium channel crucial to kidney and lung function.
elifesciences.org
Proteolytic activation of a sodium-permeable channel that aids in gas exchange and fluid homeostasis likely evolved at the water to land transition in vertebrates.
It was a delight to be part of this study w/ @okashlan on the evolution of kidney and lung ion homeostasis during the transition of vertebrates from ocean to dry land. https://t.co/i5dCiQSBzy
1
0
6
If you don’t want to see big roly-poly pandas rolling down hills in a rare DC snowstorm then LOOK AWAY
392
15K
44K
Really enjoyed @LabZhu Bokai Zhu's talk today about the 12-hour circatidal biological clock. Who knew we shared so much with clams?
journals.plos.org
Distinct from the well-known 24-hour circadian clock, this study shows that the mammalian 12-hour clock upregulates genetic information flow capacity during the two "rush hours" (dawn and dusk) in a...
0
0
1
It's hard to overstate the impact of their work. https://t.co/PPCrbCthpk
BREAKING NEWS: The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
0
0
1
Nobel Prize in Medicine to the 3 scientists that discovered HEPATITIS C. A great recognition to the greatest achievement of hepatology. Now it is time to erradicate it !!
0
16
68
NEWS: PA Sen Pat Toomey will not run for governor or reelection in 2022. Announcement expected Monday. He'll serve out his current senate term. w/ @wbender99
https://t.co/cGujTUwbxQ
inquirer.com
Toomey was widely seen as the likely Republican favorite for governor in 2022. His decision not to run for that office or for Senate could create two wide open contests on the Republican side.
401
1K
3K
Genetic consequence to the tragedy in Syria: http://t.co/KrAK2aZgCo
wired.com
When civil war broke out in Syria, Ahmed Amri immediately thought about seeds. Specifically, 141,000 packets of them sitting in cold storage 19 miles south of Aleppo.
0
0
0