Bokai Zhu lab
@LabZhu
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The Zhu lab studies the moon/tide-related 12h ultradian clock; xbp1, proteostasis, epigenetic, metabolism, aging, stress response are the key words. @AgingPitt
Aging Institute, Divison of Endocrinology and Metabolism, Department of Medicine,Univeristy of Pittsburgh School of Medicine
Joined June 2018
Left by the tides | Pitt Med Magazine | University of Pittsburgh. A nice piece on our earlier work on identifying 12h rhythms in ‘free-living” humans.
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This is a very good review on ~12h biological rhythms. Biological rhythms: Living your life, one half-day at a time | npj Biological Timing and Sleep
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Interesting work. 12h rhythms of lipid metabolism in the Drosophila fat body, independent of the circadian clock. Circadian clock-independent ultradian rhythms in lipid metabolism in the Drosophila fat body - Journal of Biological Chemistry
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RT @SamuelBHume: This is like AlphaFold, but for protein localisation rather than folding. It's a deep learning model that predicts a prote….
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RT @AgingPitt: The Aging Institute is pleased to share the most recent edition of our newsletter, The Chronos Chronicle, Winter 2025. Read….
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Fascinating work!.Circatidal control of gene expression in the deep-sea hot vent shrimp Rimicaris leurokolos | Proceedings of the Royal Society B: Biological Sciences
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Twelve-hour ultradian rhythmic reprogramming of gene expression in the human ovary during aging | Journal of Assisted Reproduction and Genetics
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A very nice perspective on ultradian rhythms!.
New Research: Re-scoping ultradian rhythms in the context of metabolism #FrontiersIn #Physiology.
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RT @AydoganLab: 🚨Pre-print Alert!🚨. THRILLED to share our new story with MANY unexpected turns, leading us into territories entirely new to….
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RT @jonathanbfine: The 2024 Nobel Prize in Literature has been awarded to ChatGPT for democratizing the creative process and freeing the wr….
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RT @JayXiaojunTan: 🦕Welcome to the Jurassic era of STING! Online @MolecularCell We uncovered a primordial role of the cGAS-STING pathway in….
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RT @PittDeptofMed: 📰New study in @MolecularCell from @AgingPitt researchers including @JayXiaojunTan and @LabZhu suggest STING may play a m….
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Epigenetic regulation of global proteostasis dynamics by RBBP5 ensures mammalian organismal health
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Achieving optical transparency in live animals with absorbing molecules | Science
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RT @DongyinGuan: We received 265 attendees per lecture in the summer seminar series. Now, we have finalized the speaker list and presentati….
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RT @SnyderShot: Our aging paper just came out. Two periods of major changes: Mid 40s and 60s. Check it out
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We are exciting to share our most recent study where we discovered ~12h rhythms of mRNA processing and proteostasis gene expression in the white blood cells of healthy humans under ‘free-living’ condition, sharing great homology to circatidal gene program.
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RT @healthspan_AUG: Let's talk about Healthy Aging. So much to do in this growing field. AGE has been on my mind lately, since we are almos….
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