Neha Khetan
@NehaKhetan4
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Quant-CompBiologist| Postdoc @Weinberger_Lab @GladstoneInst |PhD @AthaleLab @IISERPune| BE @rvce_official | Interested in mechanisms-EmergenceEvolutionEngineer
San Francisco
Joined May 2019
1/3 HIV-TIPs: Hijacker of the Hijacker! Parasite of the Parasite! Therapeutic Interfering particles #TIPs establish an #evolutionary arms race with #HIV Happy to share our @Weinberger_Lab recent publication in @ScienceMagazine #antiviral drive therapy:
science.org
Antiviral therapies with reduced frequencies of administration and high barriers to resistance remain a major goal. For HIV, theories have proposed that viral-deletion variants, which conditionally...
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Indian Cancer Genome Atlas, a pioneering initiative to map Molecular, Cellular & Omics basis of Cancer in Indian population, thanks to the founders including Anand Deshpande @anandesh
@ICGA_India
@ICMRDELHI @DBTIndia @IndiaDST @NITIAayog @MoHFW_INDIA
https://t.co/OKEzp4pfeR
aninews.in
The Indian Cancer Genome Atlas (ICGA) has launched India's first comprehensive cancer multi-omics data portal which provides open access to clinically correlated data from Indian cancer patients,...
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What is the role of emergence and broken symmetries in biological complexity? Why is quantum mechanics not enough to explain biology? Check this paper by Michael Stumpf @theosysbio, on the classic paper by @sfiscience Phil Anderson on "More is different" https://t.co/uDFVNNcsxB
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For all the fancy single cell profiling methods out there, cell morphology is surprisingly informative… and ~free.
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📢OPEN DAY IS HERE! 🤩Inviting all curious minds to NCBS. We have a lot of fun exciting science planned for you! 🆓Free and Open to curious minds of all ages! 📢Please help us spread the word! Share this with your friends and family! 🗓️13 Sept. 📍NCBS, Bengaluru
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Top 10 Manu Prakash teachings from his amazing episode of the Night Science Podcast. 1. Science is a sense of wonder; a personal sense of experience. 2. Science gives us increasing agency; you realize it’s like a car you drive with no roads. 🧵⬇️ @ManuPra18599785 @MartinJLercher
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We're excited to announce guest speakers for our Microtutor LIVE course on Fluorescence Microscopy, starting 9/9/24! These lectures will support virtual course content that students complete on their own time & weekly discussion groups with Microtutor instructors. A special thank
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3/3 Single-dose of TIPs reduced viral load in monkeys and predicted to lower HIV load below @WHO recommended transmission threshold! Delighted to have contributed #MathematicalModeling with an amazing team @FathimaPitchai, @gusvasen, Clara, @LeorWeinberger, and collaborators!
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2/3 Single-dose administration! Escape resistant! Establishes latency! #Engineered TIPs from the #Emerged Defective Interfering Particles (DIPs) – a potential for the functional cure of HIV! Works in mice and monkeys!
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This meeting @HHMIJanelia will bring together researchers to share challenges and successes in the development of new genetic tools for a broad range of non-traditional model organisms and biological problems. Learn more + apply by Oct. 29 @ https://t.co/AZC2xFewW6
@HHMINews
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30 Essays to Make You Love Biology Day 7. "Biology is more theoretical than physics," by Jeremy Gunawardena. It is often said "that biology is not theoretical," but that's not true. This essay gives examples where theory preceded & informed major discoveries. A must-read.
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"One of the most important things as a scientist is that you have to be an optimist. If you’re a pessimist, a failed experiment will tell you that the whole idea is bad and you’ll quit. When you fail you have to continue." - chemistry laureate Richard Henderson's advice.
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The international #systemsbiology conference 2024 is in #mumbai #india and the lineup is stellar. Do pls register with abstracts for a scintillating scientific programme. Venue: #iitb @iitbombay
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From preprint to journal. Our nuclear gatekeepers have successfully unlocked the gates to Cell (Journal) https://t.co/ZA1xVgZtCD
#NPC #integrativemodeling Congrats to team @dgvjayS @JoshHutchings94 @ig_ech @RoutLab_RU @salilab_ucsf @TheVillaLab Animation https://t.co/Av7fD7Yfs0
Tiny gatekeepers of our nucleus decide what gets in and out. Follow our study on Yeast and Mammalian NPC baskets and unravel the molecular structure of these cellular bouncers! Don't miss the side-by-side comparison in the video. #IntegrativeModeling
https://t.co/Fi047oKYGz
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Excited to be part of this novel antiviral therapy study! Engineered HIV-TIPs reduce viral load in monkeys, predicted to reduce transmission in humans: single-dose and escape-resistant! Congratulations to the team! @Weinberger_Lab @GladstoneInst @
science.org
A stripped-down HIV genome can interfere with normal virus replication
Scientists have developed a new weapon against HIV: a molecular mimic that invades a cell and steals essential proteins from the virus. After promising results in monkeys, scientists plan to test the new treatment in a few people.
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Dynein, a molecular motor capable of transporting cargo within a cell, generates wave-like oscillations in microtubules in a purified synthetic system, researchers in @IISERPune. This knowledge could help engineer better nanodevices. https://t.co/3kYRfxb4ED
#NatureIndia
nature.com
Nature India - The knowledge can help design better nanodevices
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I keep reminding PhD students that THE most important outcome of a PhD is not their publications, conferences, awards etc., but they themselves after this journey. PhD is a learning process in how to learn new things, solve new problems you run into. @VoicesofIndAcad @biopatrika
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Proud to share the result of an amazing collaboration with Javi Fernandez-Martinez, @RoutLab_RU , and @TheVillaLab ! https://t.co/UslJWdFKIW Congrats to @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech and the team! And check out the video by @neeleshsoni03 ! #NPC
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Microtubules and motors are extiing. Seeing them move is even more so. In case of interest look up our lab website and apply to us for #phd #positions in #modelling and #experimental #reconstitition
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Emergence of periodic beating of single microtubules with yeast cytoplasmic dyneins in-vitro and in-silico! #CollectiveDynamics @AthaleLab @Shivani_A_Yadav @Khatri_dh
1/3 We are very excited about cool results that came from a collaboration within the lab with inputs on the "Emergence of flagella-like oscillations in single microtubules driven by collective dynein transport"
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