Jennifer Young
@nano_jenn
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Bioengineer studying the tissue nanoenvironment | Asst Prof @MBIsg & @BME_NUS | National University of Singapore
Singapore
Joined May 2020
It’s finally out!!🥳 Check out our paper in @NatureMaterials on a new hybrid scaffold where we discover ECM-specific cues that regulate cardiac aging 🔗 https://t.co/Vgf1ZEersw This is the lab’s 1st research paper, led by my 1st @NUSBME PhD student @AveryRuiSun🤩 Tweetorial👇
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📅 Submission deadline: 14 May 2026 🔗 Learn more & submit here: https://t.co/uHYAuCZdyH
#ExtracellularMatrix #ECM #Mechanobiology #natureportfolio #Biophysics #TissueEngineering #Biomechanics #RegenerativeMedicine #npjBiologicalPhysicsAndMechanics (7/7)
nature.com
This Collection aims to highlight fundamental and translational advances in ECM mechanobiology.
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Let’s bring together physics, biology, and engineering to push the frontiers of ECM research. Feel free to contact me if you have questions about the Special Collection or submission process (6/7)
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- ECM mechanics in health and disease - Multiscale cell-ECM modeling - Advanced matrix mechanobiology tools - ECM in tissue engineering & regenerative medicine - Translational ECM mechanobiology - Mechanotherapeutic & AI-driven approaches (5/7)
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We welcome interdisciplinary studies (experimental, theoretical, and computational) that explore how ECM mechanical properties influence biological processes across scales. Topics of interest include: (4/7)
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From molecular mechanotransduction to tissue remodeling in health and disease, understanding ECM mechanics and interaction with cells is central to both fundamental biology and biomedical innovation (3/7)
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I’m excited to be serving as Guest Editor with Jacopo Di Russo and Delphine Gourdon! The ECM is far more than a passive scaffold. Its mechanical and biochemical properties actively shape cell behavior, tissue integrity, and organ function (2/7)
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📢 Call for paper submissions in @nature_npj npj Biological Physics & Mechanics special collection on: Mechanobiology of the Extracellular Matrix! 📅 Deadline: 14 May 2026 🔗 https://t.co/uHYAuCZdyH More info👇(1/7) #ExtracellularMatrix #ECM #Mechanobiology #natureportfolio
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My lab @MBIsg and @NUSMedicine is recruiting a fully-funded postdoc to start in Jan 2026! Interested in cell and tissue mechanics, transcriptional regulation of tissue health, or AI/ML for disease mechanobiology? Come join us in Singapore! https://t.co/qoZz02LPDY
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Huge congrats to Dr. @shen_xingyu (aka Dr. TZP) on a successful PhD defense today on #ECM & ovarian aging!! #mechanobiology Xingyu now holds special spot in lab history as the 1st PhD student grad 🎓🥳 What a pleasure to co-advise Xingyu w/Rong Li @MBIsg 🤩 📷 Lucie Kim
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https://t.co/7Qfvo2mqyg in Anatomy and Human Biology, Physiology + Honours in Physiology + COVID19 + PhDing in Mechanobiology lab = Image analysis software, FOCUST by @Seb_Amos
https://t.co/B5G6viL5JF A plugin for FIJI (ImageJ) to batch process 2D and 3D images @uwanews @ASBTE1
onlinelibrary.wiley.com
FOCUST (Fluorescent Object and Cell gpU-accelerated Segmentation Toolbox) is an open-source FIJI plugin that addresses limitations in 3D fluorescence microscopy image analysis. It provides intuitive...
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Two postdoc positions open: https://t.co/52VaOOOlwL
https://t.co/cNwL5HuFrg
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"My" latest review is online now. We need your creativity! 😎 👇👇👇 Collagen Biosynthesis and Its Molecular Ensemble: What Remains Unexplored | Biochemistry
pubs.acs.org
Collagen embodies an intriguing paradox in protein biology. Despite being one of the most abundant protein superfamilies in vertebrates and having a seemingly simple structural organization, its...
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🌴 The pipettes are parked, the data can wait — it’s time for ☀️🏄♀️ and science naps! Our July newsletter is live, featuring ECM summer vibes, cool papers, a poll, a lab introduction and a researcher spotlight that’ll warm your heart. Read it before we hit snooze 😎 👉🏖️
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Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @MBIsg, and the Dept of Physiology at @NUSingapore in the fall! More about our work on vascular mechanobiology: https://t.co/2PDzYxiE5F
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Interested in a #postdoc on cardiac #mechanobiology? Our lab has a fully funded position via our recently awarded @HFSP grant to study the biophysical processes that build insect hearts🪲🪰🫀 Come join us @MBIsg for some cool evo-devo-mechanobio work! 👇 https://t.co/BVOWW3ofLn
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Hot off the press!📢 New review from our lab led by @huanting_ong & Sriram w/@HSusapto @confinementlab @ahcells & Elnathan lab @deakin in Advanced Materials @AdvPortfolio We discuss #mechanobiology in cell engineering & manufacturing Check it out!👇 https://t.co/7X6fOWu44D
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Check out our lab's latest review by @MFarisHazwan @MBIsg @BME_NUS in Current Opinion in Cell Biology @sciencedirect 🔗 https://t.co/e7UJmw6G3G We teamed up w/Brian Aguado @ucsdbe to highlight region- & sex-specificity of #ECM signaling in the aging heart!🫀 Hope you enjoy!
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A hybrid ECM-hydrogel with tunable mechanical stiffness and biochemical composition of young or aged cardiac tissue is used to identify the specific contributions of ECM ligands and mechanics for fibroblast aging. @nano_jenn
https://t.co/1ysfJPB1Xv
nature.com
Nature Materials - A hybrid extracellular matrix–hydrogel with tunable mechanical stiffness and biochemical composition of young or aged cardiac tissue is used to identify the specific...
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2nd paper from Mechanobiologics Lab is out in Journal 'Small' @AdvPortfolio. This work led by my 1st PhD student Alka. Superb collaboration with @ahcells & Rudra Pratap @CeNSEatIISc. We discovered how confined spaces in tissue reduce tumor cell killing upon ultrasound treatment.
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