Sebastian Amos
@Seb_Amos
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Lecturer and Anatomy Discipline Lead @ UWA Medical School | Bioimage Informatics & Cancer Cell Mechanobiology
Perth, Western Australia
Joined October 2018
RT @YuSukChoi: How do cancer spheroids mechanosense in 3D?.Plz read @Danielle_Vahala 's first first-author research paper! . @Seb_Amos @Bra….
advanced.onlinelibrary.wiley.com
There is a constant need for biomaterials that offer a high degree of tuneability to greater recapitulate the variable tissue properties noted in diseased tissues, such as breast cancer. Using a...
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I was delighted to present my #BioImageAnalysis work at #ACMM27 earlier this month. Extremely humbled to receive the John Farrant Prize for the best student talk in Biological/Medical Sciences. Very excited to release this project soon! #Microscopy #ImageJ @YuSukChoi @UWAresearch
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Last week, I had a fantastic time discussing all things mechanobiology at #ISMB2022 in Sydney. Such a great experience to listen to and share our work with leaders in the field!.@YuSukChoi @SamuelJMaher @Danielle_Vahala @IanLChin @uwaresarch @uwashs @asbte @yonghwee_joe @AuSMBSoc
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RT @YuSukChoi: The whole Western Australia (Choi lab) taking off to Sydney for #ISMB2022 Samuel Maher @Danielle_Vahala Joe Tan @Seb_Amos an….
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RT @YuSukChoi: Trilogy completed by @IanLChin and @Seb_Amos on cardiac mechanobiology! .1 - H9C2/NRCM in 2D .2 - H….
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RT @YuSukChoi: 3D cardiac mechanosensation as an individual vs. spheroidal culture. Congrats to authors @IanLChin @Seb_Amos @LiviaHool @UWA….
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RT @YuSukChoi: Cardiomyocyte volume mediates mechanosensation in 3D by @IanLChin expanding our previous understanding of cardiomyocyte mech….
pubs.rsc.org
Extracellular matrix (ECM) remodeling is a major facet of cardiac development and disease, yet our understanding of cardiomyocyte mechanotransduction remains limited. To enhance our understanding of...
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RT @YuSukChoi: Showcasing the hard work of @Seb_Amos, PhD student in improving 3D imaging and volumetric analysis (photo in the right obv….
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Whether it’s in the fight against cancer or progress towards regenerative medicine, in the case of my colleague, Sam, hydrogels improve the translatability of our research… and let us capture stunning 3D datasets!.
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To study the initial steps of the metastatic cascade, I use hydrogels to mimic normal and cancerous microenvironments in 3D. This allows me to investigate how tumour growth, escape and local invasion are mechanically linked.
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My research focuses on the mechanical challenges that cancer cells must navigate to spread successfully, a process known as metastasis. I study changes to cancer cell adhesion and the mechanical conditioning that might enhance and protect them on their deadly journey.
Hydrogels are used to mimic the mechanical and chemical properties of tissues which allow for cells to be studied in more representative and translatable environments. #biozone #uwa .@UWAresearch
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RT @BioZoneUWA: BioZone PhD candidates @Seb_Amos, @Danielle_Vahala, Sam and Eric had a fantastic time participating in the @UWAPSA Research….
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RT @BioZoneWA: We're back! Meet the BioZone cohort!. Here at BioZone, we seek innovative solutions that address the increasing complexity o….
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RT @YuSukChoi: Seb (PhD student in the lab)'s review paper on 'Cancer Microenvironment: Mechanical Challenges of the Metastatic Cascade' ht….
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RT @YuSukChoi: Just saying thx to 3 honours students, Jeet (left), Seb (right) and Quinn (away) who put up with me last 8 months #UWA #mech….
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