Namrata Udeshi
@namude
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Scientist focused in proteomics and mass spectrometry | Director of Proteomics R&D Broad Institute of MIT and Harvard | Mom | Fan of cheese
Joined May 2009
We are hiring a new lab manager! Our wonderful lab manager Albert is headed off to grad school and we are looking to fill his position this summer. This is a great opportunity for a new graduate to spend a couple years immersed in research before applying to PhD or MD programs.
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Check out our new work led by @aliceyting and her lab presenting LaccID for peroxide-free labeling of cell surface proteins for PL-proteomics and EM applications.
APEX peroxidase is a versatile tool for proximity labeling and electron microscopy (EM) but its requirement for toxic H2O2 is a liability. We now report LaccID, a multicopper oxidase evolved from an ancestral fungal laccase that oxidizes aromatic substrates using non-toxic O2
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Grateful for the opportunity to learn from Don and Jeff @UVA, whose enthusiasm, curiosity and kindness have profoundly impacted my career. #teamMassSpec #OGlcNAc #ETD #proteomics
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A special thanks to my co-authors Chad Slawson and Gerald Hart for helping with this special tribute to Don and for their critical collaborations in the early 2000’s that shaped my Ph.D.
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In this paper, we reflect on the journey of O-GlcNAcylation, exploring the challenges and innovations that have shaped our understanding of this important post-translational modification.
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Excited to share our latest manuscript dedicated to the remarkable Donald F. Hunt, a true pioneer in the field of mass spectrometry and O-GlcNAc research! From Fringe to the Mainstream: How ETD MS brought O-GlcNAc to the masses
mcponline.org
O-GlcNAcylation was identified in the 1980s by Torres and Hart and modifies thousands of cellular proteins, yet the regulatory role of O-GlcNAc is still poorly understood compared to the abundance of...
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Another terrific collaboration with @JiefuBiol lab and collaborators profiling cell surface proteome human dendritic cells.
Glad to share our latest study on the cell-surface proteome of human dendritic cells, by our awesome long-term collaborators Namrata and Charles @BroadProteomics and talented undergrad @Zuzhi_Jiang (soon at @UCSF tetrad for PhD). https://t.co/e4jGWJHoqu
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Glad to share our latest study on the cell-surface proteome of human dendritic cells, by our awesome long-term collaborators Namrata and Charles @BroadProteomics and talented undergrad @Zuzhi_Jiang (soon at @UCSF tetrad for PhD). https://t.co/e4jGWJHoqu
academic.oup.com
The JI publishes peer-reviewed manuscripts describing novel findings in all areas of experimental immunology, including both basic and clinical studies.
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If you’re at ASMS, check out these fantastic talks and posters from @BroadProteomics!! Talks will cover immunopeptidomics, proteogenomics of ODG and single-cell proteomics. Posters include our latest work in HDX-MS, TargetID, Olink vs. DIA-MS for plasma, and FFPE proteomics.
For all those who are at #ASMS #ASMS2024 here is where you can find Carr Lab members sharing our latest research!
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Please check out new work from @aliceyting and all co-authors using PL methods to study protein trafficking. Another fun and exciting collaboration with Alice and the entire team. @BroadProteomics
TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase
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TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase
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We hope you check out the great work presented by these outstanding scientists @BroadProteomics during #ASMS2023.
If you’re at #ASMS2033 this week come check out these talks and posters by members of the Broad Proteomics Team!!
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LOV-Turbo is published today in @naturemethods and plasmids for LOV-Turbo are available on Addgene, here: https://t.co/wn1G6d7wmb We hope many people will use LOV-Turbo in exciting new ways! https://t.co/vHdxhUI56E If you plan to use NanoLuc BRET to activate LOV-Turbo, please
Light-regulated TurboID, or LOV-Turbo, is a feat of engineered allostery, created by @SongyiLee10 and @CheahJoleen via structure-guided design, then optimized by yeast display directed evolution. Activity is nearly undetectable in the dark state, but https://t.co/L8MswSqgkE
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Check out newly published work from our group @BroadProteomics describing an integrated workflow for measuring the immunopeptidome, proteome and PTMomes
Do you want to get as much data as possible out of your limited tumor samples? Well now you can with our MONTE workflow! Our manuscript describing the serial enrichment of immunopeptidome, ubiquitylome, proteome, phosphoproteome and acetylome is out now!
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Check out this exciting pre-print describing light-regulated TurboID from @aliceyting @SongyiLee10 @CheahJoleen and collaborators.
Light-regulated TurboID, or LOV-Turbo, is a feat of engineered allostery, created by @SongyiLee10 and @CheahJoleen via structure-guided design, then optimized by yeast display directed evolution. Activity is nearly undetectable in the dark state, but https://t.co/L8MswSqgkE
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Proud to be named a Highly Cited Researcher 2022 by @ClarivateAG. See the full list https://t.co/fVWWHj4FKI
#HighlyCited2022 (though they got my affiliation wrong :| )
clarivate.com
The Highly Cited Researchers 2025 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and...
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