BREAKING NEWS The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Dear tweeps - does anyone have great experience with an alternative to the good old radioactive based labeling and membrane blotting for Souther Blot?

This episode features the latest work from Dr. @jacob_hanna's team! Drs. @Alperen98Yilmaz, @GulbenGurhan, and collaborators generated transgene-free mouse stem cell-based embryo models from naive PSCs. 📎 https://t.co/FL9XdBOMOM 🎧 https://t.co/GLms49GzfK

Excited to share our work published in @CellStemCell! After determining a way to induce TE and PrE lineages from naive PSCs w/o transgenes to make complete embryo models, we also devised a new culture condition that can maintain Epi, PrE and TE that can generate SEMs on demand.

Online Now! Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs https://t.co/vpmrCKJaCm #stemcells

1/n Fun journey continues: Our new @CellStemCell paper out on how the Inherent & Dormant Plasticity of mouse naive PSCs can be "Exaggerated" to Directly form ~E8.5 Transgene-Free (TF) Mouse SEMs & WITHOUT inducing 8-16-Morula-like "Embryo Founder Cells".

We truly enjoyed summarizing this tour de force work in @Dev_Cell on understanding human cleavage stage ZGA arrest by using single-embryo single-cell allele-specific RNA-seq by Peng Yuan team, & catching up on other recent advancements in ZGA research https://t.co/s9CnFL61Vx

Científicos del Instituto Weizmann de Ciencias buscar comprender los enigmas del embrión humano dentro del útero - Infobae

As a Turkish student, he has always been an idol and one of the people I look up to, and it is completely deserved. @DAcemogluMIT

Developmental biology meets crystal formation science ! great work from our upstairs neighbours .

We greatly enjoyed reading and summarizing the important findings of these two new studies on LIN28 regulation of cell fate for @NatureSMB - mechanistic studies at their best! Congrats Miha @paraspeckle and all other authors https://t.co/ItPaCvLVhM https://t.co/dsjNvKFcgC

Save the date! June 7th @cdf1530 in Paris, the latest developments in the making of human pseudo-embryos in vitro🤘Open access👍 no registration 🙏RT @AMartinezArias @jacob_hanna @NRivron @nmoris @AlainChedotal @TreutleinLab #JFGuerin #ERialSebbag @the_Node

We are very excited to present the development of Zman-seq (“Zman”, Hebrew for “time”), the 1st technology that measures single-cell transcriptomes and physical time in vivo, led by @D_Birschenkaum, @CuriousKX, @FlorianIngelfi1, @AssafWeiner https://t.co/pDk6ackAtV. (1/19)

Brilliant approach from @IdoAmitLab …. This will enable things for us and many others in the stembryology field

Thank you for the opportunity to talk about out latest work on the ISSCR Digital Webinar: The Science of Integrated Human Embryo Models on 31 October 2023. Register to attend 👉 https://t.co/Ufp6YcrqnR

The Wall Street Journal @WSJ reports on Hanna lab ideas to explore human post-implantation embryo models as a source for early fetal gonads for gamete generation. Technology might make it possible someday to create an egg cell from their DNA https://t.co/7fegVl9ulg via @WSJ

Join our upcoming webinar, The Science of Integrated Human Embryo Models, on 31 October to hear the latest in embryo model research including groundbreaking work by Dr. @jacob_hanna #embryomodels #stemcells

Best Inventions 2023: Human Embryo Model While distinctly not human, the model is close enough to give researchers potential insights into fertility, miscarriage, and more, for the first time

Proud to see that our work made it to @TIME 2023 best inventions on the experimental category. Thanks to all Hannalab members @jacob_hanna for this ongoing journey.

Good news in these challenging times. Our work is on the Time's Best Inventions List.