
Muthu Vaduganathan
@mvaduganathan
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Cardiologist & Trialist @BrighamWomens @harvardmed | AE @JACCJournals | Podcast #DontMissABeat & #HFinFocus | Disclosures: https://t.co/BmQHCNyLml
Cambridge, MA
Joined July 2017
Just 5 years ago, HFpEF was described as the “stepchild” of HF with no approved therapies. Today, there are 5 US FDA therapies:.✅ Empagliflozin (#EMPEROR).✅ Dapagliflozin (#DELIVER).✅ Sotagliflozin (#SOLOISTWHF).✅ Sacubitril/Valsartan (#PARAGONHF).✅ Finerenone (#FINEARTSHF)
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Wow, the game has changed! #SURPASSCVOT meets its primary & secondary endpoints in first *head-to-head* CV outcomes trial!. Tirzepatide (dual GLP1/GIP agonist) vs Dulaglutide (GLP-1RA). including 16% lower risk of all cause mortality!.
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RT @ankeetbhatt: #CardioKidneyMetabolic (CKM) syndrome is common, affecting >90% of US adults. Can we shape care models to address pt-centr….
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RT @drbennisahmed: Effects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2….
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RT @medcentralmd: “Therapies indicated for #HF like finerenone should be continued long term without interruption or premature discontinuat….
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RT @JACCJournals: 💊💥 New trial, new strategy: Dapagliflozin + spironolactone packs a bigger biomarker punch in #HFpEF. But what’s the trade….
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RT @drbennisahmed: Cardiovascular-Kidney-Metabolic Syndrome: A Paradigm for Value-Based Care. CKM syndrome represents a unifying framework….
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RT @SarahChuzi: 🔥🔥 Check out this practical piece on CKM implementation and value-based care!.
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RT @EdinaCenko: 📢 Presenting our @LancetRH_Europe Series on CVD Inequalities at #ESCCongress Madrid!.📍 Fri Aug 29 | 13:45–15:00 | Room Zag….
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RT @JasonKatzMD: So excited to share this next paper with the readers of @JCFINT - incredible vision and perspective by an amazing authorsh….
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RT @noshreza: Our 2nd @JCFINT Article in Press is published! 🚀. This week, @zhermesMD @ankeetbhatt @mvaduganathan walk us through innovativ….
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RT @costplusdrugs: 📢 Generic Entresto is now available at Cost Plus Drugs ❗️. Sacubitril/Valsartan is now on A big….
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RT @brendonneuen: Combining SGLT2i & MRAs in Heart Failure and CKD: Playing the Long Game @JACCJournals . Our thoughts in light of recent t….
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RT @ankeetbhatt: #HFimpEF is common, but data are limited on #GDMT & outcomes. In @JACCJournals, the largest look at HFimpEF in US to date.….
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RT @escardio: In a few weeks, cardiology professionals will gather at #ESCCongress 2025 with #WCCardio for an unforgettable experience. En….
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RT @David_Ouyang: We are excited to work with @StanfordDeptMed, @SmidtHeart, @mghliver, and @KPDOR with the support of @American_Heart to r….
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RT @carlosguizars: #heartfailure improved EF.⬆️Rising prevalence.🚨Despite partial recovery, risk for MACE remains.🚦Clinical gaps and thera….
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RT @NatMetabolism: RESEARCH | @clarissamliu, @DanielJDrucker, M Véniant et al (@Amgen, @SinaiHealth). Part 1: This study and a co-pub delve….
nature.com
Nature Metabolism - This study, together with a companion manuscript, shows that in mice, weight loss as a result of GIP receptor antagonism requires and potentiates functional GLP-1 receptor...
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RT @hfcollaboratory: Out now — an analysis led by our #HFC members, the first to evaluate the inclusion of social determinants of health (S….
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