Miguel Fuentes Ramos
@miguelfr92
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🔥Out in @NatureComms!🔥We show that enriched and impoverished environments opposingly modulate the activity-dependent transcriptional program of hippocampal neurons in a cell-type specific way, with a key role for Fos/AP-1 signalling in memory functions.🧠@BarcoLab @NeuroAlc 1/4
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🔥A new study led by @BarcoLab at @NeuroAlc is published on @CellReports 🔝 Researchers show that the enzymes KDM1A & KDM5C act as epigenetic guardians, silencing inappropriate genes to keep neuronal identity. More info 👇 https://t.co/HaTCJ1aIT2
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New review out with Aysha @FEBSJournal. We discuss how dysregulated type-I interferon signalling affects brain function, with a focus on the IFN-responsive state of microglia in development and neurodegeneration. Experimental work coming soon, stay tuned! https://t.co/7wnZAySYiI
febs.onlinelibrary.wiley.com
Recent insights reveal that type I interferon (IFN-I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN-I activity is increasingly linked to neurologi...
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Incredibly happy to share the recent study in which I contributed where we characterized cell-specific epigenetic erosion of developmental genes in HD mouse striatum. Congrats to Baptiste Brulé, Karine Merienne and all the team for this amazing work! 🖥️🔻 https://t.co/NaX7fTjmA6
nature.com
Nature Communications - Loss of epigenetic information is a hallmark of cellular aging. Here, authors examine changes in the epigenetic landscape at three stages of Huntington neurodegenerative...
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Congratulations to our colleague @FedericoMiozzo for the publication of this paper!!
#JNeurosci | @FedericoMiozzo et al. used mice to investigate how a gene associated with autism spectrum disorder and depression, Protocadherin 9, plays a role synaptic dysfunction and brain pathology. This study provides important molecular and synaptic insight. @NeuroAlc
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We’re thrilled to see our image on the cover of @TrendsMolecMed! The image highlights the crucial role of epigenetics in the etiology of ASD. Many thanks to @IsraelMGuerrero for his collaboration on the design! https://t.co/JtK2Kcat0j
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2/2 Our chapter focuses on the impact of new genome-wide technologies and their application in studying activity-driven transcription. Don’t miss it! https://t.co/k1qKF2R5eR
@NeuroAlc @SergioNi92 #BarcoLab #Neuroscience
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Alongside our review, colleague Macarena Herrera shares her experience of researching and living at the beautiful Mediterranean coast, home to @NeuroAlc and @BarcoLab. 🔬☀️🌊 Take a look! https://t.co/jeb1lGxwC6
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📣WE ARE HIRING📣 We are looking for a laboratory technician to work with us in the Laboratory of Transcriptional and epigenetic mechanisms of neuronal plasticity based at the @NeuroAlc. 🔽Check it out! 🔽
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🎉Celebrating 20 years of Barco's laboratory! 🧬 A heartfelt thank you to everyone who has contributed with passion, dedication, and hard work over the years. Here’s to many more years of exciting science ahead! #BarcoLab20years @NeuroAlc
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‼️ 📣 We have just published our preview of the work from @EricJNestler lab in Neuron studying the role of H3K27me1 in mouse stress resilience to adult social defeat stress and early life stress. @rafalcala2 @NeuroAlc @NeuroCellPress Check it out here: https://t.co/vPgCdU5qXQ
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And it's a book! Together with @okaysteve, we have gathered some of the leading experts in the field who have generously contributed with a chapter of what has become the first ever book on #engram biology! 📖🔥🧠Come take a look! ⬇️⬇️⬇️ https://t.co/S00ThFw2ER
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Take a look at our latest book chapter on Engrams! Angel Barco and @miguelfr92 have collaborated with other renowned researchers to compile the latest advances on engrams. Their chapter focuses on the underlying transcriptional and epigenetic mechanisms. https://t.co/BoW4nNAdO6
link.springer.com
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📣We're excited to share our latest review article on the role of epigenetics in the etiology of ASD! Check it out here: https://t.co/VSEK15tVBm Don't miss it! 📸 @TrendsMolecMed
🔥 New review article by @BarcoLab is now published on @TrendsMolecMed 🔝 This work examines the role of epigenetic alterations, resulting from genetic and environmental influences, as a central factor in ASD, delving into its contribution to pathogenesis & treatment strategies.
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🎉 Enhorabuena a la recién nombrada hoy Dra. Marta Alaiz Noya @martalaiz2 por su defensa de #TesisIN y felicitaciones a sus directores de Tesis, el Dr. Angel Barco y la Dra. Beatriz del Blanco Pablos @Beatriz_dBlanco @BarcoLab🎉
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🎉 Enhorabuena al recién nombrado hoy Dr. Adrián Portalés Montes por su defensa de #TesisIN y felicitaciones a su directora de Tesis, la Dra. Sandra Jurado @LabSjurado🎉
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A new study led by @AlerieDe from @NeuroAlc @isabial_iis @MyelinAlicante & Denise Fitzgerald from @QUBelfast @WWIEM_QUB is now on @NatureComms 🙌 They confirm that ageing reduces the ability of regulatory T cells to enhance myelin regeneration More info 👇 https://t.co/9ICCy4nIxY
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🔥A new study led by @BarcoLab at @NeuroAlc is now published on @NatureComms 🙌 Researchers have determined the role of the Kdm1a protein in maintaining the neuronal identity and relationship with age progression More info 👇 https://t.co/FX1sNazpz0
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#SciencePhoto_IN "Neuronal storm" Author: Dr. Rafael Alcalá @Rafalcala2 Lab: Dr. Angel Barco @BarcoLab "Hippocampal neuronal primary culture expressing a plasmid coding for a red fluorescent protein (RFP). The image has been captured with @zeiss_micro Celldiscoverer7."
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