#CELLFIE for CAR T screening, out in @Nature today—a new mRNA-based platform for screening primary cells. CAR + gRNA library are delivered by lentivirus, CRISPR modifiers as electroporated mRNA. That’s more flexible and effective than existing T cell screening methods. (1/7)

The ability to design antibodies against any protein of interest has major implications for medicine, biotech, and basic science. Today, we introduce Germinal, a pipeline for epitope-targeted de novo antibody design achieving  4–22% success rates with efficient experimental

New faculty position opening @Stanford_ChEMH. Especially interested in candidates with deep expertise and vision for the future of AI/ML/computational models of biomolecules. Please RT

🚨Exciting opportunity! (In addition to post-doc openings), we’re hiring an In Vivo Research Scientist w/ @genophoria (Hani Goodarzi's Lab) @arcinstitute (Palo Alto): https://t.co/louuCuuZad Experience with advanced in vivo work preferred (survival surgeries, etc.).

Online now: Efficient stem cell-derived mouse embryo models for environmental studies

I'm thrilled to share that I'll be starting my lab ( https://t.co/h1qdyhRdgN) at the Lunenfeld-Tanenbaum Research Institute @SinaiHealth and joining @MoGen_Grad at the University of Toronto as an assistant professor this fall. 1/

@jengreitz & I are looking to hire a computational biologist/biostatistician with project management expertise to collaborate with our teams to map the regulatory code of the human genome and discover genetic mechanisms of disease. Details below https://t.co/lsyqN9kFHS Plz RT

✨Not a rainbow trout… a rainbow zebrafish 🌈 🐟 The expression of 10 different genes simultaneously including Hox genes along the body axis, somites, brain regions, skeletal muscle, and heart 🔬Video by Alice Sherrard, Gabby Jerz & Nipam Patel 🧪 #FluorescenceFriday

The Sudmant lab at UC Berkeley is seeking a postdoc to work on a fully funded NIH project to understand differences in DNA repair and somatic mutation across the primate tree of life. Please spread widely to those who may be interested

I am thrilled to share that I will be starting my lab in the Center for Pediatric Neurological Disease Research (CPNDR) at St. Jude Children’s Research Hospital as a faculty member @StJude @StJudeResearch. Deeply grateful for the incredible mentorship, support and camaraderie in

This paper is really elegant and beautiful. Researchers took a vesicle, filled it with a single type of enzyme and some protein pores, and showed that this "minimal cell," made from just three components (!!), could "actively propel itself toward an enzyme substrate gradient."

Our Issue 07 launch party in San Francisco was a smashing success. 🏏 Thanks to everyone who came and played Biology Trivia. Winning teams got copies of our DNA books, hats, and posters. It was a really fun time! See you in the fall, in Boston, for the next one. :)

Range extender mediates long-distance enhancer activity https://t.co/bFVjuSRpEh

https://t.co/0Z5jMggJsS Wow! 1,700 transgenic mice for the most comprehensive enhancer characterization ever. Leo and Axel never cease to amaze!

Postdoc position opening in my group! Research projects: pangenomes for diverse organisms, genome evolution, biocomputing, language models. Please reach out if interested!

Possible there's some unintended CasRx effect, but it seems to work. They also check for large dels and it doesn't seem toxic. Overall worth a try, good job Zongyang Lu & Zhen Liu!

For mouse engineering aficionados - an HR booster (~2x) that works on mouse embryos across sites. Yes, it's MMEJ/NHEJ double inh (AZD7648 DNA-PKcs inh + CasRx vs Polq), but the path to find this combination wasn't easy - other DNA-PKcs inh don't work in embryos, nor do siRNAs.

We’re @BlaineyLab sharing a major update to CROPseq-multi, our versatile system for CRISPR screens that is compatible with individual and combinatorial perturbations, diverse SpCas9-based technologies, and multiple high-content, single-cell readouts. https://t.co/GIar9mgX3Z

Can an AI model predict perfectly and still have a terrible world model? What would that even mean? Our new ICML paper formalizes these questions One result tells the story: A transformer trained on 10M solar systems nails planetary orbits. But it botches gravitational laws 🧵

I'm super excited to share that I will be joining the Department of Biology at @Stanford as an Assistant Professor in October 2025! I’ll also be a member of the Stanford Stem Cell Institute @CellStanford. Incredibly grateful to be starting my dream job!🧠🧬🖥️