Timothy Fuqua
@timothy_fuqua
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Postdoc in the @WagnerEvolution lab interested in enhancers, promoters, developmental biases, and de-novo emergence. Opinions are my own. He/him. 🏳🌈
Zurich, Switzerland
Joined September 2016
I'm super excited to announce that we have published the official "Version of Record" for our work on promoter emergence and evolution! A thread below for thsoe who want to know more:.
elifesciences.org
Mutagenizing sequences enriched with promoter motifs creates gene expression de novo, and helps to understand promoter logic, regulatory evolution, and the birth of de novo genes.
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Some cool work on TFBS evolution coming out of our group!.
🚨 New preprint from the @WagnerEvolution lab @UZH_Science, with Andrei Papkou (@0000_2104):.🧬 "The fitness landscape of the E. coli lac operator is highly rugged in two environments".🔗 🧡 Powered by URPP Evolution in Action @uzh_evolution.Follow the 🧵.
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Hey y'all, I may be unemployed starting from October. If you have any leads on biotech / postdoc positions in the German-speaking part of Switzerland, I'd greatly appreciate a message. I'm great with Data Analysis, Molecular Biology, and Teaching. (Plz RT)
timothyfuqua.com
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Happy to announce that our study on the latent cis-regulatory potential of mobile DNA is out!.
nature.com
Nature Communications - The mechanism and extent to which transposons can alter the gene expression of their hosts is not well understood. This study finds that in the IS3 family of transposable...
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Hey #TEsky hivemind, a student today asked me what percentage of human Transposable Elements (TEs) are autonomous vs non-autonomous (i.e. require a "helper"TE for transposition). Any ideas? Please RT!.
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Woahhhhh.
Resolution of a human super-enhancer by targeted genome randomisation
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If you’re in Göttingen tomorrow, come hear me talk about our experiments to research how regulatory DNA evolves and emerges from non-regulatory DNA. Also I’m in Göttingen this evening if anyone wants to grab a drink/dinner!.
2025 will start with a #GoenomiX talk by @timothy_fuqua from @UZH_en. He will present his work "Exploring the biases and mechanisms of regulatory DNA emergence" on Thu, Jan 9, 2025 at 14:15. Seminar will be offered in hybrid format. Check details here:
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