david_mf_evans
@evans1_d
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Professor of Statistical Genetics
Brisbane, Queensland
Joined April 2016
Investigating potential causal effects of maternal smoking on offspring handedness using a proxy gene-by-environment (GxE) Mendelian randomization design out today: with Daisy Crick @mendel_random @medland_sarah.
link.springer.com
Behavior Genetics - Hand preference first appears in early development, yet twin studies and GWAS show that only a minority of variance is explained by heritable genetic factors. Using UK Biobank...
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RT @JianZengR: We have received over 40 registrations and 7 scholarship applications. If you are interested in this opportunity to learn co….
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RT @DiabetologiaJnl: .@evans1_d and @Dr_GHMoen (@IMBatUQ @UniOslo_MED) used winsorisation when performing #GWAS of birthweight and discover….
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This included a low frequency missense variant in ABCC8, a gene involved in congenital hyperinsulinism, neonatal diabetes mellitus and mature onset diabetes of the young, that was estimated to be responsible for a massive 170 gram increase in birthweight amongst carriers.
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We found that a winsorization strategy performed best in terms of locus detection doubling the number of significant associations including 25 completely novel loci.
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Genetics explained at least part of the correlation between low BW and increased risk of many cardiometabolic traits and diseases.
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We found evidence for a separate set of genes underlying low BW compared to BW within the normal range.
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We investigated if the genetic factors operating at the extremes of BW were different to those in the normal range, estimated the genetic correlation between extremes of BW and cardiometabolic disease, and investigated whether analyzing extreme BW improved ability to detect loci.
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Our article investigating the genetics of high and low birthweight (BW) out today:. with @Dr_GHMoen @NMWarrington @CarolineBritoN1 @danielldhwang.
link.springer.com
Diabetologia - Low birthweight infants are at increased risk not only of mortality, but also of type 2 diabetes mellitus and CVD in later life. At the opposite end of the spectrum, high birthweight...
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Registration for the IMB Genetics and Genomics Winter School July 7-11 is now open:.
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Is there any high profile GxE interaction finding from the noughties that has not turned out to be completely bogus?. with @GiulioCentorame @NMWarrington @explodecomputer @Jack_Geng_Wang @mendel_random putting the final nail in the coffin.
link.springer.com
Behavior Genetics - Breastfeeding is hypothesised to benefit child health and cognitive functioning by providing long-chain polyunsaturated fatty acids, which are essential for brain development....
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If you have a spare moment, it would be great if you could support Nathan Palpant and Glenn King as finalists for the 2024 People’s Choice Awards.
shapingaustraliaawards.com.au
We're delighted to present 15 exceptional finalists shortlisted across three awards categories, spanning research, teaching and community service.
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Registration now open for the Genetic and Epigenetic Epidemiology course in beautiful Florence 7th to 11th of July 2025:. With Gib Hemani (@explodecomputer ), @PaulYousefi and Matt Suderman.
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RT @danielldhwang: Our method, #DINGO (Direct and INdirect analysis of Genetic lOci), named after Australian wild dog 🐕, now in @NatureComm….
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RT @JohnF1CDO: Sleepiness and low energy are common symptoms of DEMENTIA. It’s why he takes Adderall. Cognitive Doctor discusses Trump’s Br….
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RT @Dr_GHMoen: @shannon_durso and I wrote a piece for the @ConversationEDU 👇. Does drinking coffee while pregnant cause ADHD? Our study sho….
theconversation.com
Previous research has shown a link between caffeine intake and a brain development difficulties for the child. But our new study controlled for factors such as genes and showed there’s no causal link.
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RT @BehaviorGenetic: After 23 years, we thank John Hewitt and Christina Hewitt for their extraordinary service as Editor-in-Chief and Manag….
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RT @LoicYengo: Glad to have our new study reconciling linkage and association studies using data from 120K sib pairs finally published in @….
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