Matthew Moffa
@matthewmof31
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Infectious Diseases physician at @AHNtoday | #stewardship | Pittsburgh native & sports fan | Proud minivan owner | Tweets my own/not med advice
Pittsburgh, PA
Joined January 2018
How long is long enough?🤔 I channeled my inner @BradSpellberg to give this talk on duration of therapy at the #ThreeRiversASP2022 Interested? Follow the 🧵 below Not interested? Go Rx a zpak for a cold #IDtwitter #MedTwitter #MedEd #pharmed #shorterisbetter
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The CDC just rewrote its vaccine and autism page to claim that saying "vaccines do not cause autism" is not evidence-based. This is false. The evidence is overwhelming & consistent. 🧵 https://t.co/kJ4ntrlPhA
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🆕🔥🦴 Our 2025 Update to @WikiGuidelines for the Management of Pyogenic Osteomyelitis in Adults 🌟 @BradSpellberg 🧪 Diagnosis 🔹 Nuclear scans & paravertebral biopsies → high accuracy 🔹 Bone histopathology > culture 🔹 MRSA nares negative → >90% NPV for DFO 🔹 PEDD >
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Check out our ASP Team’s latest newsletter! 💊🦠🆔 #idccm #IDCCM #InfectiousDisease #CriticalCareMedicine #ASP #AntimicrobialStewardship #IDforMe
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When it comes to AI and medical advice: it's slick, confident, sometimes wrong. Evidence-based AI: less flashy, more accurate. Read the difference. @teddyrosenbluth @EvidenceOpen @WebMD @IDSAInfo
https://t.co/b5hRv5VyXQ
blogs.jwatch.org
A journalist recently reached out to ask about the shingles vaccine. We mostly talked through the usual topics — how common shingles is, why the vaccine works so well, and side effects. Plus, the...
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Thanks to @absteward for finding 3rd RCT of short course tx for appendicitis, & honorable mention RCTs for appendicitis (rectal metronidazole, seriously?) and for cIAI (5 vs. 7-10 d). All added to the website references, and the new trial added to Table! https://t.co/1oaAT6Cybb
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Aaron Siri is misrepresenting flu vaccine evidence by selectively citing studies. Doing this after the deadliest non-pandemic pediatric flu season on record — 280 children dead, 89% of whom were not fully vaccinated — is unconscionable. Here’s what the data actually show. 🧵
For anyone contemplating getting an influenza vaccine (flu shot) or planning to pressure or mandate someone else to get one: A meta-analysis of existing flu shot studies of healthy children by Cochrane (effectively owned by vaccine zealot Bill Gates) concluded that despite
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Data are very weak. https://t.co/9ZKHFFXpeD
Time to rethink SBP prophylaxis? Antibiotic prophylaxis for SBP in cirrhosis has been standard since the 1990s—but the new 🔥ASEPTIC trial, presented at #TLM25, just challenged that. 📊 Bactrim vs placebo in cirrhosis + ascites (no prior SBP): ➡️ No survival benefit for primary
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Time to rethink SBP prophylaxis? Antibiotic prophylaxis for SBP in cirrhosis has been standard since the 1990s—but the new 🔥ASEPTIC trial, presented at #TLM25, just challenged that. 📊 Bactrim vs placebo in cirrhosis + ascites (no prior SBP): ➡️ No survival benefit for primary
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Thanks to @ABsteward for finding another Oral Is the New IV RCT: 5253 children < 2 mos with Possible Serious Bacterial Infections! Master Table updated below, website updated with references. Seriously, how much evidence do the IV pushers need to change? https://t.co/F9Whl4lYvM
Discontinuation of the injectable antibiotics and switching to oral antibiotics with early hospital discharge in young infants with moderate mortality-risk PSBI signs was effective and safe in diverse low-income and middle-income countries in Africa & Asia https://t.co/bJMo3ngI0x
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We’re still thinking about our achievements and presentations from last week at ID week. Everyone’s dedication and hard work continue to elevate our program! Only 33 days until Match! 🦠 #collaborativelearning #research #camaraderie
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Our systematic review on Covid-19, RSV, and influenza vaccines was just published in @NEJM. With federal vaccine guidance processes in flux, we felt independent evidence synthesis was crucial for the 2025-2026 respiratory virus season. 🧵 https://t.co/6Wb1pvnYku
nejm.org
Changes in the vaccine advisory process in the United States have disrupted immunization guidance, which reinforces the need for independent evidence review to inform decisions regarding immunizati...
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Vanco pulse taper should supplant Vanco 10 days for CDI at all stages Now --- fidaxo vs Vanco pulse taper needs larger numbers and longer follow up See how fidaxo catches up to Vanco 10 days at day 56+ @DrEmilyMcD @ABsteward
👨🏫Great presentation by Dr. Johnson on RCT of Vancomycin Taper/Pulse and Fidaxomicin compared to Vancomycin for Treatment of First or Second rCDI 🔥 The VA CSP596 trial 📋3 arms 1) Vancomycin taper/pulsed (VAN-TP) 2) Fidaxomicin x10d (FDX) 3) Vancomycin x10d (VAN) #IDWeek2025
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What the DOTS trial of Staph bacteremia tells us: • Dalbavancin d1 and d8 vs daily IVs for WEEKS • No left-sided IE/CNS/prosthetics • Dalba not superior by DOOR endpoint, but similar clinical outcomes. Big implications for inpt care. More in link ⬇️⬇️⬇️
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.@SecKennedy presents a clear and present danger to the American people and their families. This week, even more of our colleagues in the fields of medicine, public health and patient advocacy join us in calling for his resignation. Our full statement: https://t.co/Ytm7a0EhXz
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1/ Two days of ACIP chaos: Self-described "rookies" eliminated universal COVID vaccine recommendations, added FDA-debunked theories to consent forms, and voted outside their legal authority. They literally don't know what they're doing or what they're allowed to do.🧵
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HEPATITIS B vaccine Recommended at birth because infected newborns have a 90% chance of developing chronic hepatitis B, versus 5-10% for adults. Of those chronically infected, 15-25% die prematurely from cirrhosis or liver cancer.🧵
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Thanks to @ABIMFoundation for posting the video of my recent lecture on the @LAGeneralMed Policy to Override Policies. For those of you who know my lectures, this one is among the most entertaining. And it's only 10 min. Check it out & implement policy! https://t.co/1pRRahGCwG
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