Marko Rubinic
@markorubinicc
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🏳️🌈 | he/him | Ph.D. student focused on host-pathogen interactions, and sex. ♀️♂️ @IatsenkoIgor lab @mpiib_berlin
Berlin, Germany
Joined April 2014
Happy to share our new preprint! Sex Differences in Drosophila Intestinal Metabolism Contribute to Sexually Dimorphic Infection Outcome and Alter Gut Pathogen Virulence
biorxiv.org
Sexual dimorphism in infection outcomes is a pervasive phenomenon, the underlying mechanisms of which remain incompletely understood. Here, utilizing Pseudomonas entomophila intestinal infection in...
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New trigger of human #lupus found by the @MajerOlivia Lab, @_HarshitaMishra. Mutations in UNC93B1 disrupt degradative sorting of TLR7 and cause #autoimmunty leading to systemic lupus erythematosus. 📄 Now published in @SciImmunology:
science.org
The BORC complex prevents human autoimmune disease by controlling endosomal TLR7 levels.
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Nov 18th #LGBTQSTEMDay and #FlyDay
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04.11.2023 in front of 📍 Naturkundemuseum Berlin 🥰😍😍
12:30 - 13:00 Aranzazu Arias-Rojas: Microbial Harmony: Illuminating Pathways to Lifelong Health. (EN) Neher Aseem Parimoo: Narratives of Discovery: Empowering Diversity in Science (EN)
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Almost all @IatsenkoIgor lab is presenting at @EDRC2023. @yiyu80925777 poster 403 @aranzazuariasr poster 410 @markorubinicc poster 413 @alex_hrdina poster 405 and Igor speaking at the Immunity and symbiosis session
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always happy and excited to see my friend's work 🥰👩🔬 https://t.co/TuZ6h8k7ay
science.org
PARP14 is an antiviral PARP that combines ADP-ribosylation writer, reader and eraser functions in one polypeptide.
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Our latest work from @mpiib_berlin led by a fantastic #PhD student @aranzazuariasr is published in @PNASNews! Resistance to host antimicrobial peptides mediates resilience of gut commensals during infection and aging in Drosophila | PNAS
pnas.org
Resilience to short-term perturbations, like inflammation, is a fundamental feature of microbiota, yet the underlying mechanisms of microbiota resi...
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How do we estimate the impact of pneumococcal #vaccines? Check out @mpiib_berlin's breakdown of @anabelle_wong's paper on using #LassoRegession to estimate the impact of these vaccines! https://t.co/CtORnh0vgE
mpiib-berlin.mpg.de
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As a professor, pursue the careers of your PhD students and postdocs instead of pursuing your own. I know it may sound strange and even provocative. But in fact it is how it’s supposed to be. Unfortunately, a personal gain is the biggest motivation for many professors. More
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🎉Excited to share our first piece of work from the Majer Lab @MajerOlivia! 📢We describe how #BORC complex regulates #TLR7 degradation and prevents human #lupus. Grateful to all the authors for their contribution!
biorxiv.org
Hyperactive Toll-like receptor (TLR) 7 signaling has long been appreciated as a driver of autoimmune disease by breaking tolerance to self-nucleic acids in mouse models[1][1]–[5][2]. Recently,...
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📢Check out our intro chapter and 4 protocols to study @reproductive behaviours in flies. @CSH Neurobiology of Drosophila lab manual. Written together with Anne @PhilipsbornL and Galit Ophir. Thanks to editors @AlexCarlKeene @ScottishWaddell for the invite to contribute.
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Basic research and fundamental mechanistic studies remain critical ingredients of scientific and medical progress even during the age of “Big Data,” argue @hholdenthorp and @mbyaffe in a new @SciSignal Editorial. https://t.co/eRUdf31OB1
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A celebration of researchers that study sex-specific differences! https://t.co/qz9EYakBzF
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The @IatsenkoIgor Lab is offering a #PhDposition at the @mpiib_berlin. We are looking for candidates with interests in mechanisms of microbial pathogenesis and microbe-microbe interactions or the regulation of innate immune responses. More info: https://t.co/Vr7LugIy9X
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🔭 Are you looking for a PhD in #infectionbiology or #immunology? Do you want to be part of an excellent research environment? The 2023 call of the IMPRS-IDI graduate school is now open with 10 PhD projects in Berlin 👉 Join us: https://t.co/uzI3A3tAFv
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Our first paper from @mpiib_berlin was just published in @PLOSPathogens We characterized host defenses and identified the virulence factors of human and #drosophila pathogen Providencia alcalifaciens #InFlies. https://t.co/a1Q2xL4yqm
journals.plos.org
Author summary Pathogens express special molecules or structures called virulence factors to successfully infect a host. By identifying these factors, we can learn how hosts fight and how pathogens...
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