MajiLab (Protein Engineering and Neurobiology Lab)
@maji_lab
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IIT-Bombay | BSBE | We explore several aspects of functional & disease amyloids | We play with scaffolds of amyloid based hydrogels | NDD, Organoids, Cancer |
Joined January 2019
Finally, it's online...!! Our work linking α-synuclein phase separation and aggregation is published in @NatureChemistry . @iitbombay @BsbeIitb @TIFRScience @ETH_en congratulations to all. @SamirKMaji1 @SoumikRay5 @NituRSingh @ranjithpa @NmrAshutosh Link: https://t.co/6Hdv6GILQC
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We are looking for highly motivated, freshly graduated candidates with extensive expertise in cell biology, biophysics and molecular biology to join us as Postdoctoral Research candidates in our lab.
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“SCAN Annual Symposium 2024” ended on a high note with lots of informative talks and cheerful faces. Hope to see you in next annual symposium. @Scaniitb @BsbeIitb @iitbombay @SamirKMaji1
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It was a great pleasure to speak at an exciting neurodegeneration conference organized by Samir @SamirKMaji1 @maji_lab @BsbeIitb @iitbombay. I learned so much from several fascinating talks. Photo credit: Bhumika @pippalbhumika (a PhD student of my first PhD student @Jain_Lab).
So nice to speak at TIFR Mumbai this morning. Had great discussions after my seminar. Arrived at IIT Bombay this afternoon. I will give a talk at a neurodegeneration conference at IIT Bombay tomorrow morning. A view from my 10th floor room at Padmavihar guest house at IIT Bombay:
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Thank you @GhoshRoyLab . The neuronal regeneration story from your lab was fascinating and its prospects in reversal of age related neuropathies is profound. Thank you @SamirKMaji1 for bringing together so many of us
@Debojyoti_C mesmerised everyone with his approach with CRISPR therapy. A great progress in improving the precision of CAS9 towards treating rare genetic diseases.. looking forward to hearing you soon at @DBT_NBRC Thanks @SamirKMaji1 and @iitbombay for organising this event.
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#Day_1 spent well. We had an amazing lineup of speakers who delivered talks at "SCAN Annual Symposium 2024". @ViditaVaidya @NeelanjanaSeng1 @poonam_thakur6 et al. Looking forward to #Day_2
@Scaniitb @iitbombay @BsbeIitb @SamirKMaji1
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The first Annual Symposium of the Sunita Sanghi Centre of Aging and Neurodegenerative Diseases (SCAN) @iitbombay - led by @SamirKMaji1 and supported by Sharad Sanghi, IITB alumnus - wonderful to see this effort take of so well
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Great insight into abeta oligomer formation in relation to Alzheimer’s disease in a talk delivered by @SudiptaMaiti13 from @TIFRScience In SCAN @iitbombay meeting. @SamirKMaji1
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Our latest work published in @NatureComms! unveils the diverse world of liquid-liquid phase separation unravelling the unique phase regimes, we discovered electrostatic, hydrophobic, and H-bonding interactions as key players. https://t.co/xKK1YkoD0F Congrats to all the authors.
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We have one DST-funded JRF position. Please apply before 20th September.
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Join Us for the inauguration!
#IITB will host @pratimamurthy for inauguration of Sunita Sanghi Centre of Ageing and Neurodegenerative Diseases (SCAN) on Jan 9, 2023. The Centre will focus on early detection, diagnosis & prognosis of #neurodegenerativedisorders. Join live at 10:50 am: https://t.co/XKqIxRyvHC
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Join us for the inauguration of the Sunita Sanghi Centre of Aging & Neurodegenerative diseases ( SCAN) at IIT Bombay!
Join us for the inauguration of Sunita Sanghi Centre of Aging & Neurodegenerative diseases ( SCAN) at IIT Bombay!
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Diwali celebration of @maji_lab, wishing everyone a very happy Diwali, may the festival of lights fill your life with glow, happiness and sparkle of joy #Diwali2022
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When @Pradeep_kadu_ joined as a fresh Ph.D. student, he was super interested establishing structure-functions of various metal nanoparticles in our lab. As usual, we promote research in diverse fields but with a broad interest in amyloid. Nanoscale
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Proud moment for @maji_lab @SamirKMaji1 Congratulation... Dr @DebalinaDatta1 and Dr @KomalPatel_1 Congratulation to Abhishek Goswami for the 'Institute Silver Medal' and Shreya Chakraborty for the 'Shubhada Mulekar Joshi award'. #60thconvocation_IITB 💐💐💐
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Congratulations @ambuja_n !!!! Proud moment for the @maji_lab. Dr. Gargi Vishnoi Memorial Best Ph.D. Thesis Award” (2021-22). @SamirKMaji1 @iitbombay @BsbeIitb
#60thconvocation_IITB
The article ''by Dr @ambuja_n where she has shown the direct evidence of cellular transformation by prion-like p53 amyloid infection'' is accepted to be published in @J_Cell_Sci @Co_Biologists Find out more 👇 https://t.co/CIXQl4Qmat
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Our work on understanding mechanism of cellular transformation and cancer pathogenesis by p53 amyloid formation now out in @J_Cell_Sci
https://t.co/p66GBlNNKj Work led by our past Ph.D student @ambuja_n with collaborations @Tushar_RCB, @unescorcb and @mkjolly15, @iiscbangalore
journals.biologists.com
Summary: p53 amyloid formation alters key cellular pathways to induce oncogenic traits leading to cellular transformation.
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Our latest article published in JPCL demonstrates the evidence for seed size-dependent α-Synuclein amyloid amplification and cellular processes implicated in PD pathogenesis, Congratulations @ARUNIMAS8 and all co authors https://t.co/NtNsPciMSv
pubs.acs.org
The size of amyloid seeds is known to modulate their autocatalytic amplification and cellular toxicity. However, the seed size-dependent secondary nucleation mechanism, toxicity, and disease-associ...
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Our recent publication in "eLife" on the lifecycle of prolactin and galanin hormone amyloid. Congratulations to @debdeepchatter and all the authors #eLife
https://t.co/3aOG2zxvpQ
elifesciences.org
Co-aggregation, amyloid formation, and unidirectional cross-seeding of prolactin and galanin for their efficient storage in secretory granules of pituitary and subsequent functional hormone release.
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We urgently require Nb2 (rat lymphoma) cell line for our ongoing research work. It would be of great help if anyone can provide the cells and/or give information about the availability of this in any cell repositories or any labs in India. We will appreciate your help.
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