Samrat Mukhopadhyay
@SamratLabMohali
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Professor & JC Bose Fellow @IISERMohali Editor @BiophysJ Studying biological condensates involved in physiology/disease Attended @IIScBangalore @ScrippsResearch
IISER Mohali, Punjab, India
Joined July 2015
Five years ago, in October 2020, my institute appointed me to a full professorship. On this occasion, I select 10 representative research papers we published in the past 5 years. It's been an absolute privilege to work with my super-talented, industrious, and fearless students.
Happy to share that after a long-drawn-out process, my institute has removed the first word of my academic rank. First time in my academic life, I have got a "one-word" description of my position. I thank my incredible students for their contributions and my family for support.š
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Aficionados of peptide conformation will readily recognize the unique Ļ-Ļ Ramachandran map of Ī±-aminoisobutyric acid (Aib), a sterically crowded but achiral, non-proteinogenic amino acid that favors 3āā-helix. Work of Raman, Ramachandran & Balaram meets: https://t.co/x8VLQdSrkN
This is another compelling example of how purely curiosity-driven science for science's sake can become useful after many years. Thanks, @kvijayraghavan, for bringing this brilliant article by @curiouswavefn to our attention. https://t.co/RzToVHZQah
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This inspirational song is relevant to every sphere of life. For sure, every scientist can relate to this iconic song from the 1974 Indian movie Imtihan. Mellifluous, sonorous, dulcet, melodic, expressive voice of the great Kishore Kumar.
Another inspirational song from Kishore Kumar. The song has many versions, coming at different occasions in the movie. This one comes in the climax of the movie. Tanu makes a great pair with VK. Music LP. Lyrics Majrooh.
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This is another compelling example of how purely curiosity-driven science for science's sake can become useful after many years. Thanks, @kvijayraghavan, for bringing this brilliant article by @curiouswavefn to our attention. https://t.co/RzToVHZQah
How P. Balaram and Isabella Karleās work contributed to the structural foundation of the wave of GLP-1 agonists. An excellent post by @curiouswavefn (I suspect he is an institution and not a person; given the breadth and depth of his posts; though this one is right up his alley)
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Looking forward to attending & speaking at Pacifichem 2025 @Pacifichem, the International Chemical Congress of Pacific Basin Societies, next week in Honolulu, Hawaii. Thanks, Masaki Okumura (Tohoku Univ) & Takahiro Muraoka (Tokyo Univ) for the invitation. https://t.co/BSot4Fw501
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Have you integrated APOL1 genetic testing into your practice? Discover the No-Cost APOL1 Genotyping Program for eligible patients sponsored by Vertex Pharmaceuticalsāhelping you deliver precision care without added cost. Learn more today!
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We had a wonderful lab dinner with Sonia Longhi and Frederic Carriere at Wyndham Mohali. We greatly enjoyed scientific discussions with both Sonia and Fred. They are very excited about the science my students and colleagues are doing at IISER Mohali.
Sonia Longhi @LonghiSonia (@CNRS Marseille) is visiting my lab at @IISERMohali as part of our Indo-French Centre for the Promotion of Advanced Research project @IFCPAR. Today, she gave a lecture. We also had a luncheon with some of my colleagues (recipients of CEFIPRA projects).
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It was wonderful to host Shiv Grewal @grewalsh at @IISERMohali today. Shiv gave a beautiful talk on heterochromatin propagation and the epigenetic landscape. We had a stimulating discussion after his lecture. It was also great to have him visit my single-molecule biophysics lab.
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Sonia Longhi @LonghiSonia (@CNRS Marseille) is visiting my lab at @IISERMohali as part of our Indo-French Centre for the Promotion of Advanced Research project @IFCPAR. Today, she gave a lecture. We also had a luncheon with some of my colleagues (recipients of CEFIPRA projects).
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It was so nice to have my former PhD student, Anamika Avni @AnamikaAvni (currently a postdoctoral fellow at the Scripps Research Institute in San Diego, California), visit my lab. Anamika, Mily @MilyBhLab, and I had a nice dinner tonight at Mimas in Jubilee Junction, Mohali.
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The latest Microsoft Research Forum episode is now available on-demand. Explore purposeful research and its real-world impact.
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My 15th PhD student, Lisha Arora @aroralisha20, will soon be joining Xavier Salvatella's lab as a postdoctoral fellow at IRB (Institute for Research in Biomedicine), Barcelona, Spain @IRBBarcelona. Congrats and all the best, Lisha, for your future endeavors and continued success!
Yesterday, we had an amazing dinner with the members of my lab and @MilyBhLab at our apartment. It was fun (I was made to play guitaršøand sing old songsš). This was a homecoming for my former student @Harshita3110 & a send-off for @aroralisha20, who is leaving for her postdoc.
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My current PhD student, Anuja Walimbe @anuja_walimbe & former PhD student, Ashish Joshi @AshishJ87810510 (currently a postdoc at Scripps) got married today. Many of my students are attending the wedding in Delhi today. Congratulations to Anuja & Ashish for their new beginning.š
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STOP or SENSE? A new study shows that in some archaea, all TAG codons (normally a stop codon) are reassigned to pyrrolysine (Pyl: pyrrolineated lysine), the 22nd proteinogenic amino acid (note that the 21st was selenocysteine from TGA, another stop codon). https://t.co/myL8LjBUgF
Some archaeaāan ancient group of microorganismsāhave an entirely novel genetic code, according to a new study in Science. Their genetic code reassigns a DNA āstopā signal to incorporate the rare amino acid pyrrolysine into their proteins. The findings expand our understanding
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Finally, I got last year's cover page framed and placed it on my office wall. I co-edited this exciting special issue on biological condensates for the Biophysical Journal (2024). The cover art of multiphasic protein-RNA condensates was from my lab's work. https://t.co/SGuXZTo2Y2
Our "Biological Condensates" special issue has now been published in @BiophysJ @CellPressNews. Thanks to my incredible co-editors @LaskerKeren & @GaliaLab. The cover image is from my lab @Sandeep61011718 & @RoopsieK. Read our editorial & exciting articles: https://t.co/SGuXZTo2Y2
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Ep. 3 of Nationwide Amplified: Tai McNeely, co-founder of His & Her Money, shows how purpose + determination turn obstacles into opportunitiesāand inspire community along the way.
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Happy to share our latest paper published in PCCP (Physical Chemistry Chemical Physics) @PCCP @RoySocChem. Congratulations to my PhD student, @Jaspreet_Tiet @TIETofficial. Thanks to ANRF-POWER and MoE-STARS for supporting our research. Here's the link: https://t.co/MJVkfGH8uM
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I fondly recall the IDC 202 (Chemical Biology) course that I credited in the 2023 Monsoon sem, taught by none other than @SamratLabMohali at @IISERMohali . It truly reshaped my understanding of science and history.
It was an amazing experience teaching the first-year biology class of 300 students, many of whom hadn't studied biology in high school. Many of them said they immensely enjoyed my course and became very excited about biology. Thank you, class of 2030! Some pictures from a student
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It was an amazing experience teaching the first-year biology class of 300 students, many of whom hadn't studied biology in high school. Many of them said they immensely enjoyed my course and became very excited about biology. Thank you, class of 2030! Some pictures from a student
Last week, I started teaching the freshman biology class (BIO 101), which I'm very excited about. I'm sharing one of my introductory slides (now revised) on the 3 pillars of modern biology - evolution, genetics, and the molecular nature of genetic material. Exciting times ahead!
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Some HD photos of my talk at IISER Kolkata (just received from the organizers).
It was wonderful to visit and speak at IISER Kolkata today. My old friend, IISc integrated PhD classmate, Prof. Debangshu Choudhury, chaired the session and introduced me. It was lovely to interact with so many of my friends. Thank you so much for hosting me at IISER Kolkata.
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āA voyage to Europe in the summer of 1921 gave me the first opportunity of observing the wonderful blue opalescence of the Mediterranean Sea. It seemed not unlikely that the phenomenon owed its origin to the scattering of sunlight by the molecules of the water. To test this
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Snow-capped Himalayas while flying this afternoon from Kolkata to Chandigarh (~ 4x - 10x magnification).
It was wonderful to visit and speak at IISER Kolkata today. My old friend, IISc integrated PhD classmate, Prof. Debangshu Choudhury, chaired the session and introduced me. It was lovely to interact with so many of my friends. Thank you so much for hosting me at IISER Kolkata.
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It was wonderful to visit and speak at IISER Kolkata today. My old friend, IISc integrated PhD classmate, Prof. Debangshu Choudhury, chaired the session and introduced me. It was lovely to interact with so many of my friends. Thank you so much for hosting me at IISER Kolkata.
Dear friends, colleagues & students at IISER Kolkata @iiserkol: You're welcome to attend my talk (Title: Lighting up biomolecular condensates) at the Smart Materials, Methods & Applications conference (Sat, Nov 15, 12:30 PM at the MN Saha Lecture Theatre). https://t.co/RPMXAehATf
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Dear friends, colleagues & students at IISER Kolkata @iiserkol: You're welcome to attend my talk (Title: Lighting up biomolecular condensates) at the Smart Materials, Methods & Applications conference (Sat, Nov 15, 12:30 PM at the MN Saha Lecture Theatre). https://t.co/RPMXAehATf
smma2025.wixsite.com
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